Results 71 to 80 of about 1,080 (170)

Cloning, expression and preliminary characterization of VapBC-4 Toxin-Antitoxin module from Leptospira interrogans serovar Copenhageni [PDF]

open access: yes, 2023
A leptospirose é uma zoonose causada pela bactéria espiroqueta aeróbia do gênero Leptospira, sendo a Leptospira interrogans sorovar Copenhageni uma das maiores responsáveis pelos casos em seres humanos da doença no Brasil.
Azevedo, Bruna Oliveira Pigatto
core   +1 more source

Why tRNA acquisition could be relevant to bacteriophages?

open access: yesMicrobial Biotechnology, Volume 17, Issue 4, April 2024.
We highlight the role and advantages of tRNA genes in phages, and a perspective about the use of phages with tRNA genes in biotechnological applications to contribute to new perspectives among the scientific community. Abstract In this opinion, we discuss the role of tRNAs in phage biology and their importance in DNA replication and phage‐host ...
Carlos O. Lomeli‐Ortega   +1 more
wiley   +1 more source

Type II Toxin–Antitoxin Systems in the Unicellular Cyanobacterium Synechocystis sp. PCC 6803

open access: yesToxins, 2016
Bacterial toxin–antitoxin (TA) systems are genetic elements, which are encoded by plasmid as well as chromosomal loci. They mediate plasmid and genomic island maintenance through post-segregational killing mechanisms but may also have milder effects ...
Stefan Kopfmann   +2 more
doaj   +1 more source

Safety and efficacy of a reduced frequency viral monitoring strategy for Epstein‐Barr virus, cytomegalovirus, and BK polyomavirus post‐kidney transplant: A quality assurance initiative

open access: yesClinical Transplantation, Volume 38, Issue 4, April 2024.
Abstract Background There is variability in recommended viral monitoring protocols after kidney transplant. In response to increased demand for laboratory testing during the COVID‐19 pandemic, the Transplant Manitoba Adult Kidney Program updated its monitoring protocols for cytomegalovirus (CMV), Epstein‐Barr virus (EBV), and BK polyomavirus (BKV) to a
Christie Rampersad   +10 more
wiley   +1 more source

VapB-1 targets VapC-1 to the vapB-1 translation initiation region. [PDF]

open access: yes, 2013
Gel shift products from a titration of VapB-1 into samples following VapC-1 binding to (A) 50TIR or (B) 50US at a 100∶1 molar ratio of protein to DNA.
Sehresh Saleem (329519)   +2 more
core   +1 more source

The protein‐only RNase Ps, endonucleases that cleave pre‐tRNA: Biological relevance, molecular architectures, substrate recognition and specificity, and protein interactomes

open access: yesWIREs RNA, Volume 15, Issue 2, March/April 2024.
Three distinct classes of PRORP evolved to cleave the 5′ leader sequence from pre‐tRNA. Beyond available structure, kinetic, and thermodynamic data, there is more to learn about the protein‐interaction network, substrate specificity, and disease‐linked mutations related to PRORP.
Catherine A. Wilhelm   +4 more
wiley   +1 more source

The mechanistic basis of the membrane‐permeabilizing activities of the virulence‐associated protein A (VapA) from Rhodococcus equi

open access: yesMolecular Microbiology, Volume 121, Issue 3, Page 578-592, March 2024.
Rhodococcus equi virulence‐associated protein A (VapA) is a membrane‐permeabilizing virulence factor that enables Rhodococcus equi to survive within phagosomes. We show that after binding to model membranes, VapA inserts preferentially at integrity‐reduced positions, reduces membrane fluidity, and forms specific membrane domains that serve as ...
Christian Nehls   +4 more
wiley   +1 more source

On the Scale of Particle Clustering Induced by Inhomogeneous Entrainment‐Mixing in Mixed‐Phase Cumulus Clouds

open access: yesGeophysical Research Letters, Volume 51, Issue 4, 28 February 2024.
Abstract In mixed‐phase cumulus clouds, droplets and ice crystals are inhomogeneously distributed, such spatial inhomogeneity can be enhanced by inhomogeneous entrainment as it can strengthen the particle clustering, which may further influence the phase partitioning and interactions among hydrometeors. However, the scale of particle clustering induced
Yiting Liu   +7 more
wiley   +1 more source

Circular dichroism of VapB and VapC confirmed predicted secondary structure. [PDF]

open access: yes, 2014
(A) The VapB and VapC CD spectra were recorded in the wavelength range of 195–255 nm as average of five scans at 20°C. Measured ellipticities, θ (mdegree), were converted to molar mean residue ellipticities, [θ] (degree.cm2.dmol−1).
André L. Sanson (602171)   +8 more
core   +1 more source

Pseudomonas syringae coffee blight is associated with the horizontal transfer of plasmid‐encoded type III effectors

open access: yesNew Phytologist, Volume 241, Issue 1, Page 409-429, January 2024.
Summary The emergence of new pathogens is an ongoing threat to human health and agriculture. While zoonotic spillovers received considerable attention, the emergence of crop diseases is less well studied. Here, we identify genomic factors associated with the emergence of Pseudomonas syringae bacterial blight of coffee. Fifty‐three P.
Kathryn J. McTavish   +10 more
wiley   +1 more source

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