Results 71 to 80 of about 1,032 (144)
Determination of VapC sequence-specificity using MALDI-TOF MS and urea-denaturing PAGE.
, 2018 932 RNA Oligo 5 VapC39 MALDI-TOF MS results. RNA Only 0 min and 60 min refer to negative control assay reactions with no VapC protein; 5, 15, 30 and 60 min represent a time course assay with VapC39. Data analysed by Bruker Data Analysis.
Joanna L. Hicks (5706827) +4 more
core +1 more source
, 2023 A leptospirose é uma zoonose causada pela bactéria espiroqueta aeróbia do gênero Leptospira, sendo a Leptospira interrogans sorovar Copenhageni uma das maiores responsáveis pelos casos em seres humanos da doença no Brasil.
Azevedo, Bruna Oliveira Pigatto
core +1 more source
Molecular target of enteric VapC toxins and regulation of vapBC transcription by conditional cooperativity [PDF]
, 2011 The uibiquitous Type II toxin – antitoxin (TA) loci encode two proteins, a toxin and an antitoxin. The antitoxin combines with and neutralizes a cognate toxin. Usually, the TA genes form an operon that is transcribed by a single promoter located upstream
Kristoffer Skovbo Winther +1 more
core
VapB-1 targets VapC-1 to the vapB-1 translation initiation region.
, 2013 Gel shift products from a titration of VapB-1 into samples following VapC-1 binding to (A) 50TIR or (B) 50US at a 100∶1 molar ratio of protein to DNA.
Sehresh Saleem (329519) +2 more
core +1 more source
Circular dichroism of VapB and VapC confirmed predicted secondary structure.
, 2014 (A) The VapB and VapC CD spectra were recorded in the wavelength range of 195–255 nm as average of five scans at 20°C. Measured ellipticities, θ (mdegree), were converted to molar mean residue ellipticities, [θ] (degree.cm2.dmol−1).
André L. Sanson (602171) +8 more
core +1 more source
, 2018 Type II toxin-antitoxin (TA) systems play a critical role in the establishment and maintenance of bacterial dormancy. They are composed of a protein toxin and its cognate protein antitoxin.
Lauren R. Walling, J. Scott Butler
core +1 more source
Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry
, 2012 The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest TA family, little is known about
Cook, Gregory M. +13 more
core +1 more source
Model for the regulation of the vapBC-1 locus.
, 2013 (A) During colonization under favourable conditions, the VapBC-1 complex binds to and autorepresses TA operon transcription. (B) Stress induces Lon and Clp proteases that degrade VapB-1, releasing active VapC-1 toxin.
Sehresh Saleem (329519) +2 more
core +1 more source
Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control
, 2015 The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
core
, 2009 A leptospirose é uma zoonose mundial causada por bactéria do gênero Leptospira. O desenvolvimento de uma vacina de subunidade eficaz seria de grande interesse em saúde pública.
Luana Melo Lopes, Lopes, Luana Melo
core +1 more source