Results 51 to 60 of about 1,147 (168)
Protective immune response against Rhodococcus equi: An innate immunity‐focused review
Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira +4 more
wiley +1 more source
Disorganized thalamic subregional functional connectivity in bipolar I disorder
MedComm, Volume 5, Issue 11, November 2024.FIGURE 1 Flowchart of inclusion and exclusion criteria, and resting‐state functional connectivity (FC) analysis of subcortical regions and thalamic subregions. A total of 151 participants were enrolled. All participants were scanned with high‐resolution MRI. After data collection, preprocessing and seed‐based FC analysis were then performed.
Xipeng Long +9 more
wiley +1 more source
A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study
JMIR Medical InformaticsAbstract Background The digitalization of health care has increased the demand for efficient data exchange, emphasizing semantic interoperability. SNOMED Clinical Terms (SNOMED CT), a comprehensive terminology with over 360,000 medical concepts, supports this need.
Tessa Ohlsen +2 more
openaire +3 more sources
Automated discovery and phylogenetic analysis of new toxin-antitoxin systems
BMC Microbiology, 2008 Background Although often viewed as elements "at the service of" bacteria, plasmids exhibit replication and maintenance mechanisms that make them purely "selfish DNA" candidates.
Milinkovitch Michel C +2 more
doaj +1 more source
MicrobiologyOpen, Volume 13, Issue 5, October 2024.In this study, the genome of a new thermophilic cyanobacterium, Thermosynechococcaceae cyanobacterium sp. Okahandja, isolated from a hot spring near Okahandja in Namibia, was sequenced. Additionally, cultivations were conducted at elevated temperatures of 40, 50, and 55°C, followed by analyses of the respective adapted proteomes based on the annotated ...
Nathanael D. Arnold +11 more
wiley +1 more source
Crystal structure of proteolyzed VapBC and DNA‐bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca 2+ ‐dependent ribonuclease [PDF]
The FASEB Journal, 2019 Abstract Bacterial toxin‐antitoxin (TA) system has gained attention for its essential roles in cellular maintenance and survival under harsh environmental conditions such as nutrient deficiency and antibiotic treatment. There are at least 14 TA systems in Salmonella enterica
DongWon, Park +7 more
openaire +2 more sources
The Great Codon Escape: Vacating Codons for Genetic Code Expansion and Ribosome Stalling
Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.Abstract In ribosomal synthesis of peptides and proteins, genetic information is translated into an amino acid polymer according to the genetic code, which describes the translational command encoded by each codon. However, parts of the genetic code can be adjusted to customize translations.
Antonius J. P. Hopstaken +2 more
wiley +1 more source
Environmental Microbiology, 2017 Summary When abruptly exposed to toxic levels of hexavalent uranium, the extremely thermoacidophilic archaeon Metallosphaera prunae , originally isolated from an abandoned uranium mine, ceased to grow, and concomitantly exhibited heightened levels of cytosolic ribonuclease ...
Arpan, Mukherjee +5 more
openaire +3 more sources
BMC Microbiology, 2012 Background Nontypeable Haemophilus influenzae (NTHi) is a significant human pathogen responsible for respiratory tract infections and the most common cause of recurrent otitis media. Type II toxin-antitoxin (TA) systems are genetic elements that code for
Ren Dabin, Walker Anna N, Daines Dayle A
doaj +1 more source
Clinical Transplantation, Volume 38, Issue 5, May 2024.Abstract Background Immunosuppression reduction for BK polyoma virus (BKV) must be balanced against risk of adverse alloimmune outcomes. We sought to characterize risk of alloimmune events after BKV within context of HLA‐DR/DQ molecular mismatch (mMM) risk score.
Christie Rampersad +14 more
wiley +1 more source