Results 51 to 60 of about 877 (123)
MicrobiologyOpen, Volume 13, Issue 5, October 2024.In this study, the genome of a new thermophilic cyanobacterium, Thermosynechococcaceae cyanobacterium sp. Okahandja, isolated from a hot spring near Okahandja in Namibia, was sequenced. Additionally, cultivations were conducted at elevated temperatures of 40, 50, and 55°C, followed by analyses of the respective adapted proteomes based on the annotated ...
Nathanael D. Arnold +11 more
wiley +1 more source
The Great Codon Escape: Vacating Codons for Genetic Code Expansion and Ribosome Stalling
Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.Abstract In ribosomal synthesis of peptides and proteins, genetic information is translated into an amino acid polymer according to the genetic code, which describes the translational command encoded by each codon. However, parts of the genetic code can be adjusted to customize translations.
Antonius J. P. Hopstaken +2 more
wiley +1 more source
BMC Microbiology, 2012 Background Nontypeable Haemophilus influenzae (NTHi) is a significant human pathogen responsible for respiratory tract infections and the most common cause of recurrent otitis media. Type II toxin-antitoxin (TA) systems are genetic elements that code for
Ren Dabin, Walker Anna N, Daines Dayle A
doaj +1 more source
Clinical Transplantation, Volume 38, Issue 5, May 2024.Abstract Background Immunosuppression reduction for BK polyoma virus (BKV) must be balanced against risk of adverse alloimmune outcomes. We sought to characterize risk of alloimmune events after BKV within context of HLA‐DR/DQ molecular mismatch (mMM) risk score.
Christie Rampersad +14 more
wiley +1 more source
A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study
JMIR Medical InformaticsAbstract Background The digitalization of health care has increased the demand for efficient data exchange, emphasizing semantic interoperability. SNOMED Clinical Terms (SNOMED CT), a comprehensive terminology with over 360,000 medical concepts, supports this need.
Tessa Ohlsen +2 more
openaire +3 more sources
Why tRNA acquisition could be relevant to bacteriophages?
Microbial Biotechnology, Volume 17, Issue 4, April 2024.We highlight the role and advantages of tRNA genes in phages, and a perspective about the use of phages with tRNA genes in biotechnological applications to contribute to new perspectives among the scientific community. Abstract In this opinion, we discuss the role of tRNAs in phage biology and their importance in DNA replication and phage‐host ...
Carlos O. Lomeli‐Ortega +1 more
wiley +1 more source
Type II Toxin–Antitoxin Systems in the Unicellular Cyanobacterium Synechocystis sp. PCC 6803
Toxins, 2016 Bacterial toxin–antitoxin (TA) systems are genetic elements, which are encoded by plasmid as well as chromosomal loci. They mediate plasmid and genomic island maintenance through post-segregational killing mechanisms but may also have milder effects ...
Stefan Kopfmann +2 more
doaj +1 more source
Clinical Transplantation, Volume 38, Issue 4, April 2024.Abstract Background There is variability in recommended viral monitoring protocols after kidney transplant. In response to increased demand for laboratory testing during the COVID‐19 pandemic, the Transplant Manitoba Adult Kidney Program updated its monitoring protocols for cytomegalovirus (CMV), Epstein‐Barr virus (EBV), and BK polyomavirus (BKV) to a
Christie Rampersad +10 more
wiley +1 more source
WIREs RNA, Volume 15, Issue 2, March/April 2024.Three distinct classes of PRORP evolved to cleave the 5′ leader sequence from pre‐tRNA. Beyond available structure, kinetic, and thermodynamic data, there is more to learn about the protein‐interaction network, substrate specificity, and disease‐linked mutations related to PRORP.
Catherine A. Wilhelm +4 more
wiley +1 more source
Molecular Microbiology, Volume 121, Issue 3, Page 578-592, March 2024.Rhodococcus equi virulence‐associated protein A (VapA) is a membrane‐permeabilizing virulence factor that enables Rhodococcus equi to survive within phagosomes. We show that after binding to model membranes, VapA inserts preferentially at integrity‐reduced positions, reduces membrane fluidity, and forms specific membrane domains that serve as ...
Christian Nehls +4 more
wiley +1 more source