Results 51 to 60 of about 1,032 (144)
Clinical Transplantation, Volume 38, Issue 5, May 2024.Abstract Background Immunosuppression reduction for BK polyoma virus (BKV) must be balanced against risk of adverse alloimmune outcomes. We sought to characterize risk of alloimmune events after BKV within context of HLA‐DR/DQ molecular mismatch (mMM) risk score.
Christie Rampersad +14 more
wiley +1 more source
Type II Toxin–Antitoxin Systems in the Unicellular Cyanobacterium Synechocystis sp. PCC 6803
Toxins, 2016 Bacterial toxin–antitoxin (TA) systems are genetic elements, which are encoded by plasmid as well as chromosomal loci. They mediate plasmid and genomic island maintenance through post-segregational killing mechanisms but may also have milder effects ...
Stefan Kopfmann +2 more
doaj +1 more source
Analysis of purified recombinant proteins by SDS-PAGE revealed VapC dimerization.
, 2014 (A) VapB purified from the soluble fraction of E. coli extracts (B) VapC expressed as inclusion bodies, before [NP] or after [P] pressurization in buffer containing 0.5 M L-arginine; (C) VapB and VapC purified from the soluble fraction of E.
André L. Sanson (602171) +8 more
core +1 more source
Why tRNA acquisition could be relevant to bacteriophages?
Microbial Biotechnology, Volume 17, Issue 4, April 2024.We highlight the role and advantages of tRNA genes in phages, and a perspective about the use of phages with tRNA genes in biotechnological applications to contribute to new perspectives among the scientific community. Abstract In this opinion, we discuss the role of tRNAs in phage biology and their importance in DNA replication and phage‐host ...
Carlos O. Lomeli‐Ortega +1 more
wiley +1 more source
Clinical Transplantation, Volume 38, Issue 4, April 2024.Abstract Background There is variability in recommended viral monitoring protocols after kidney transplant. In response to increased demand for laboratory testing during the COVID‐19 pandemic, the Transplant Manitoba Adult Kidney Program updated its monitoring protocols for cytomegalovirus (CMV), Epstein‐Barr virus (EBV), and BK polyomavirus (BKV) to a
Christie Rampersad +10 more
wiley +1 more source
Fis, VapC-1 and VapBC-1 bind the vapB-1 TIR.
, 2013 (A) The sequence of the 50TIR indicating the putative Fis binding site (underline) and the inverted repeat regions (arrows). (B) Gel shift products from samples containing 50TIR alone (lane 1) and 10, 30, 150 or 600 molar ratios of Fis to DNA.
Sehresh Saleem (329519) +2 more
core +1 more source
WIREs RNA, Volume 15, Issue 2, March/April 2024.Three distinct classes of PRORP evolved to cleave the 5′ leader sequence from pre‐tRNA. Beyond available structure, kinetic, and thermodynamic data, there is more to learn about the protein‐interaction network, substrate specificity, and disease‐linked mutations related to PRORP.
Catherine A. Wilhelm +4 more
wiley +1 more source
Molecular Microbiology, Volume 121, Issue 3, Page 578-592, March 2024.Rhodococcus equi virulence‐associated protein A (VapA) is a membrane‐permeabilizing virulence factor that enables Rhodococcus equi to survive within phagosomes. We show that after binding to model membranes, VapA inserts preferentially at integrity‐reduced positions, reduces membrane fluidity, and forms specific membrane domains that serve as ...
Christian Nehls +4 more
wiley +1 more source
Geophysical Research Letters, Volume 51, Issue 4, 28 February 2024.Abstract In mixed‐phase cumulus clouds, droplets and ice crystals are inhomogeneously distributed, such spatial inhomogeneity can be enhanced by inhomogeneous entrainment as it can strengthen the particle clustering, which may further influence the phase partitioning and interactions among hydrometeors. However, the scale of particle clustering induced
Yiting Liu +7 more
wiley +1 more source
Leptospiral VapC toxin cleaves tRNAfMet and is inhibited by the VapB antitoxin.
, 2014 Unless specified, the reactions were carried out under the following general condition: 5 pmol VapC was incubated with 3 ρmol of tRNAfMet in 10 mM Hepes pH 7.5, 15 mM KCl, 1 mM DTT, 10 mM MgCl and 10% glycerol at 37°C for 30 min and analyzed by ...
André L. Sanson (602171) +8 more
core +1 more source