Results 61 to 70 of about 1,135 (166)
Environmental Microbiology, 2017 Summary When abruptly exposed to toxic levels of hexavalent uranium, the extremely thermoacidophilic archaeon Metallosphaera prunae , originally isolated from an abandoned uranium mine, ceased to grow, and concomitantly exhibited heightened levels of cytosolic ribonuclease ...
Arpan, Mukherjee +5 more
openaire +3 more sources
Characterisation of VapC in Mycobacterium smegmatis [PDF]
, 2016 Members of the VapC family of proteins cleave RNA at specific sites in order to regulate biological processes with a cell. Characterization of the sites targeted by a specific protein using conventional biochemical techniques is resource intensive.
Willcock, Duncan Mark Koorey
core
Clinical Transplantation, Volume 38, Issue 5, May 2024.Abstract Background Immunosuppression reduction for BK polyoma virus (BKV) must be balanced against risk of adverse alloimmune outcomes. We sought to characterize risk of alloimmune events after BKV within context of HLA‐DR/DQ molecular mismatch (mMM) risk score.
Christie Rampersad +14 more
wiley +1 more source
Binding between VAPC and NS5B.
, 2013 (a) Far-UV CD spectrum of HCV NS5B. (b) One-dimensional 1H NMR spectrum of HCV NS5B. Blue arrows are used to indicate very up-field NMR resonance peaks characteristic of a well-folded protein with tight tertiary packing. (c) Superimposition of 1H-15N NMR
Shaveta Goyal (315569) +6 more
core +1 more source
Type II Toxin–Antitoxin Systems in the Unicellular Cyanobacterium Synechocystis sp. PCC 6803
Toxins, 2016 Bacterial toxin–antitoxin (TA) systems are genetic elements, which are encoded by plasmid as well as chromosomal loci. They mediate plasmid and genomic island maintenance through post-segregational killing mechanisms but may also have milder effects ...
Stefan Kopfmann +2 more
doaj +1 more source
Why tRNA acquisition could be relevant to bacteriophages?
Microbial Biotechnology, Volume 17, Issue 4, April 2024.We highlight the role and advantages of tRNA genes in phages, and a perspective about the use of phages with tRNA genes in biotechnological applications to contribute to new perspectives among the scientific community. Abstract In this opinion, we discuss the role of tRNAs in phage biology and their importance in DNA replication and phage‐host ...
Carlos O. Lomeli‐Ortega +1 more
wiley +1 more source
3D model of leptospiral VapC closely matches the experimental X-ray structure of Shigella's VapC.
, 2014 Alignment of the sequences of VapCs from S. flexneri and L. interrogans is shown. On the left panel, the structure model (ribbon) of VapC from L. interrogans (green) was superimposed to the VapC template from S. flexneri (white) (PdB: 3TND-C).
André L. Sanson (602171) +8 more
core +1 more source
Clinical Transplantation, Volume 38, Issue 4, April 2024.Abstract Background There is variability in recommended viral monitoring protocols after kidney transplant. In response to increased demand for laboratory testing during the COVID‐19 pandemic, the Transplant Manitoba Adult Kidney Program updated its monitoring protocols for cytomegalovirus (CMV), Epstein‐Barr virus (EBV), and BK polyomavirus (BKV) to a
Christie Rampersad +10 more
wiley +1 more source
WIREs RNA, Volume 15, Issue 2, March/April 2024.Three distinct classes of PRORP evolved to cleave the 5′ leader sequence from pre‐tRNA. Beyond available structure, kinetic, and thermodynamic data, there is more to learn about the protein‐interaction network, substrate specificity, and disease‐linked mutations related to PRORP.
Catherine A. Wilhelm +4 more
wiley +1 more source
Molecular Microbiology, Volume 121, Issue 3, Page 578-592, March 2024.Rhodococcus equi virulence‐associated protein A (VapA) is a membrane‐permeabilizing virulence factor that enables Rhodococcus equi to survive within phagosomes. We show that after binding to model membranes, VapA inserts preferentially at integrity‐reduced positions, reduces membrane fluidity, and forms specific membrane domains that serve as ...
Christian Nehls +4 more
wiley +1 more source