Results 81 to 90 of about 1,080 (170)

A DNA damage-activated kinase phosphorylates a transcriptional repressor to control bacterial immune pathway expression

The EMBO Journal
Bacteria encode numerous stress-response pathways that protect their hosts against both internal and external threats. A key question is how these pathways are regulated, especially anti-phage immune pathways that mediate host-cell killing.
Lydia R Chambers, Phoolwanti Rani, Ryan K Min, Elizabeth Villa, Kevin D Corbett   +4 more
doaj   +1 more source

Impact on transient stability of self-synchronisation control strategies in grid-forming power converters

International Journal of Electrical Power & Energy Systems
Grid-forming voltage source converters (GFM-VSCs) are emerging as a solution for integrating renewable energy resources (RERs) into power systems. GFM-VSCs need a self-synchronisation strategy to ensure that all converters and generators in the power ...
Régulo E. Ávila-Martínez, Xavier Guillaud, Javier Renedo, Luis Rouco, Aurelio Garcia-Cerrada, Lukas Sigrist   +5 more
doaj   +1 more source

Epidermal growth factor‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) suppressed the growth of hepatocellular carcinoma cells by promoting Semaphorin 3B(SEMA3B)

Cancer Medicine, 2019
Aim Epidermal growth factor‐containing fibulin‐like extracellular matrix protein 1(EFEMP1) has been found to be involved in the occurrence and development of many cancers.
Jiangfeng Hu, Bensong Duan, Weiliang Jiang, Sengwang Fu, Hengjun Gao, Lungen Lu   +5 more
doaj   +1 more source

Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry [PDF]

, 2012
The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest TA family, little is known about
Cook, Gregory M., Mackay, Joel, Cursons, Raymond T., Duyvestyn, Johanna Maria, Mckenzie, Joanna L., Smith, Tony C., Bendak, Katerina, Smith, Tony, Cursons, R. A.Y., Mackay, Joel P., Arcus, Vickery L., Duyvestyn, Johanna M., McKenzie, Joanna Leigh, https://orcid.org/   +13 more
core   +1 more source

A VapBC Toxin-Antitoxin Module is a Post-Transcriptional Regulator of Metabolic Flux in Mycobacteria [PDF]

, 2012
Published ahead of print 24 February 2012 The largest family of toxin-antitoxin (TA) modules are encoded by the vapBC operons, but their roles in bacterial physiology remain enigmatic.
Cook, Gregory M., Gardner, Paul P., Smith, Tony C., Ruthe, Alaine, McKenzie, Joanna L., Berney, Michael, Ruthe, A., Arcus, V.L., McKenzie, J.L., Gardner, P.P., Smith, T.C., Berney, M., Arcus, Vickery L., Robson, J., Robson, Jennifer, https://orcid.org/, Cook, G.M.   +16 more
core   +1 more source

Model for the regulation of the vapBC-1 locus. [PDF]

, 2013
(A) During colonization under favourable conditions, the VapBC-1 complex binds to and autorepresses TA operon transcription. (B) Stress induces Lon and Clp proteases that degrade VapB-1, releasing active VapC-1 toxin.
Sehresh Saleem (329519), Dayle A. Daines (329520), Susan D. Cline (329518)   +2 more
core   +1 more source

Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control [PDF]

, 2015
The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
core  

Cloning, expression and purification of proteins, vaccine candidates from Leptospira interrogans sorovar Copenhageni. Evaluation of immunogenic and functional characteristics. [PDF]

, 2009
A leptospirose é uma zoonose mundial causada por bactéria do gênero Leptospira. O desenvolvimento de uma vacina de subunidade eficaz seria de grande interesse em saúde pública.
Luana Melo Lopes, Lopes, Luana Melo
core   +1 more source

VapC-1 of nontypeable Haemophilus influenzae is a ribonuclease [PDF]

, 2007
Nontypeable Haemophilus influenzae (NTHi) organisms are obligate parasites of the human upper respiratory tract that can exist as commensals or pathogens.
Wu, Mack H, Yuan, Sarah Y, Daines, Dayle A   +2 more
core  

Mechanism of RNA cleavage by VapC from Pyrobaculum aerophilum [PDF]

, 2012
Proteins belonging to the PIN-domain family are widespread across bacteria, archaea and eukaryotes. PIN-domain structures are well characterised and contain three highly conserved acidic residues that are orientated to form the active site of the enzyme.
Duyvestyn, Johanna Maria
core