Results 81 to 90 of about 1,032 (144)

Mechanism of RNA cleavage by VapC from Pyrobaculum aerophilum

, 2012
Proteins belonging to the PIN-domain family are widespread across bacteria, archaea and eukaryotes. PIN-domain structures are well characterised and contain three highly conserved acidic residues that are orientated to form the active site of the enzyme.
Duyvestyn, Johanna Maria
core  

Competition binding of 50TIR and 50US by Vap proteins.

, 2013
Gel shift products from addition of 50US substrate into samples containing 50TIR substrate and either (A) VapBC-1 or (B) VapC-1 at a 150∶1 molar ratio of VapC-1 protein to DNA. VapB-1 and VapC-1 are at a 3∶1 molar ratio in the VapBC-1 samples, but VapC-1∶
Sehresh Saleem (329519), Dayle A. Daines (329520), Susan D. Cline (329518)   +2 more
core   +1 more source

The Biochemistry of VapBC Toxin-Antitoxins

, 2011
The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey ...
McKenzie, Joanna Leigh
core  

Crystal structure of the VapBC-15 complex from Mycobacterium tuberculosis reveals a two-metal ion dependent PIN-domain ribonuclease and a variable mode of toxin-antitoxin assembly

, 2014
Although PIN (PilT N-terminal)-domain proteins are known to have ribonuclease activity, their specific mechanism of action remains unknown. VapCs form a family of ribonucleases that possess a PIN-domain assembly and are known as toxins. The activities of
Matthias, Wilmanns, Gourinath, Samudrala, Wilmanns, Matthias, Das, Uddipan, Tiruttani Subhramanyam, Udaya Kumar, Srinivana, Alagiri, Srinivasan, Alagiri, Pogenberg, Vivian, Subhramanyam, Udaya Kumar Tiruttani   +8 more
core   +1 more source

The Biology and Biochemistry of PhoH2 proteins

, 2013
PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core  

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

Eukaryotic PIN (PilT N-terminal) domain proteins are ribonucleases involved in quality control, metabolism and maturation of mRNA and rRNA. The majority of prokaryotic PIN-domain proteins are encoded by the abundant vapBC toxin—antitoxin loci and inhibit
Gerdes K, Winther KS
core  

Neuronal activity in the primate motor thalamus during visually triggered and internally generated limb movements.

, 1999
Single-unit recordings were made from the basal-ganglia- and cerebellar-receiving areas of the thalamus in two monkeys trained to make arm movements that were either visually triggered (VT) or internally generated (IG).
J. F. Stein, Stein, JF, R. E. Passingham, Miall, R. C., Van Donkelaar, P., Passingham, RE, R. C. Miall, Passingham, Richard, van Donkelaar, P, Miall, RC, Passingham, R. E., Stein, J. F., P. van Donkelaar   +12 more
core   +1 more source

Masking of errors in transmission of VAPC-coded speech

, 1990
A subjective evaluation is provided of the bit error sensitivity of the message elements of a Vector Adaptive Predictive (VAPC) speech coder, along with an indication of the amenability of these elements to a popular error masking strategy (cross frame ...
Cox, Neil B., Froese, Edwin L.
core  

Studies about the toxin-antitoxin module VapBC-1 of Leptospira interrogans sorovar Copenhagen

A leptospirose é uma zoonose de distribuição mundial e a linhagem L. interrogans sorovar Copenhageni é a responsável pelo maior número de casos humanos de leptospirose no Brasil. Seu genoma foi sequenciado, contribuindo para o entendimento dos mecanismos
Damiano, Deborah Kohn
core   +1 more source

Specificity Determinants of Homologous VapBC Toxin-Antitoxin Systems

, 2020
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Microbiology and Immunology, 2018.Type II toxin-antitoxin (TA) systems are ubiquitous in bacteria and archaea, where they play a pivotal role in the establishment and ...
Walling, Lauren R., Butler, J. Scott
core