Results 41 to 50 of about 877 (123)
Brain and Behavior, Volume 10, Issue 10, October 2020., 2020 Our purpose was to find a link between thalamocortical connectivity measures at term equivalent age and two‐year neurodevelopmental outcome in 58 infants following preterm birth. Using probabilistic diffusion tractography, we found that injury or dysmaturation of tracts emerging from ventral‐specific and various nonspecific thalamus projecting to late ...
Andras Jakab +5 more
wiley +1 more source
Prophage encoding toxin/antitoxin system PfiT/PfiA inhibits Pf4 production in Pseudomonas aeruginosa
Microbial Biotechnology, Volume 13, Issue 4, Page 1132-1144, July 2020., 2020 PfiT/PfiA in Pf4 prophage forms a type II toxin‐antitoxin system in Pseudomonas aeruginosa. PfiT inhibits production of Pf4 phage. Summary Pf prophages are ssDNA filamentous prophages that are prevalent among various Pseudomonas aeruginosa strains. The genomes of Pf prophages contain not only core genes encoding functions involved in phage replication,
Yangmei Li +5 more
wiley +1 more source
Regulation of the vapBC-1 toxin-antitoxin locus in nontypeable Haemophilus influenzae.
PLoS ONE, 2012 Nontypeable Haemophilus influenzae (NTHi) are human-adapted commensal bacteria that can cause a number of chronic mucosal infections, including otitis media and bronchitis.
Susan D Cline +2 more
doaj +1 more source
Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN‐domain (VapC) protein from a toxin‐antitoxin operon [PDF]
Proteins: Structure, Function, and Bioinformatics, 2008 Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon Richard D. Bunker, Joanna L. McKenzie, Edward N. Baker, and Vickery L. Arcus* 1Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand ...
Richard D, Bunker +3 more
openaire +2 more sources
Predicting drug‐perturbed transcriptional responses using multi‐conditional diffusion transformer
Quantitative Biology, Volume 14, Issue 1, March 2026.Abstract Drug‐perturbed transcriptomes are important for personalized medicine and drug discovery. Nevertheless, the existing high‐throughput screening and sequencing techniques for drug‐perturbed transcriptomes remain expensive and time‐consuming. In this study, we propose a novel multi‐condition diffusion transformer model, designated as perturbation
Qifan Hu, Zeyu Chen, Jin Gu
wiley +1 more source
Environmental Microbiology, 2017 Summary When abruptly exposed to toxic levels of hexavalent uranium, the extremely thermoacidophilic archaeon Metallosphaera prunae , originally isolated from an abandoned uranium mine, ceased to grow, and concomitantly exhibited heightened levels of cytosolic ribonuclease ...
Arpan, Mukherjee +5 more
openaire +3 more sources
Crystal structure of proteolyzed VapBC and DNA‐bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca 2+ ‐dependent ribonuclease [PDF]
The FASEB Journal, 2019 Abstract Bacterial toxin‐antitoxin (TA) system has gained attention for its essential roles in cellular maintenance and survival under harsh environmental conditions such as nutrient deficiency and antibiotic treatment. There are at least 14 TA systems in Salmonella enterica
DongWon, Park +7 more
openaire +2 more sources
Protective immune response against Rhodococcus equi: An innate immunity‐focused review
Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira +4 more
wiley +1 more source
Disorganized thalamic subregional functional connectivity in bipolar I disorder
MedComm, Volume 5, Issue 11, November 2024.FIGURE 1 Flowchart of inclusion and exclusion criteria, and resting‐state functional connectivity (FC) analysis of subcortical regions and thalamic subregions. A total of 151 participants were enrolled. All participants were scanned with high‐resolution MRI. After data collection, preprocessing and seed‐based FC analysis were then performed.
Xipeng Long +9 more
wiley +1 more source
Automated discovery and phylogenetic analysis of new toxin-antitoxin systems
BMC Microbiology, 2008 Background Although often viewed as elements "at the service of" bacteria, plasmids exhibit replication and maintenance mechanisms that make them purely "selfish DNA" candidates.
Milinkovitch Michel C +2 more
doaj +1 more source