Results 41 to 50 of about 1,032 (144)

Binding of VAPC-43 mutant with NS5B.

, 2013
(a) Far-UV CD spectrum of VAPC-43 mutant. (b) Superimposition of 1H-15N NMR HSQC spectra of VAPC-43 mutant in the absence of (blue) and in the presence of unlabeled NS5B at a molar ratio of 1∶2.0 (red) (VAPC-43 mutant:NS5B).
Shaveta Goyal (315569), Haina Qin (143174), Garvita Gupta (158903), Megha Haridas Upadya (315570), Jianxing Song (143189), Vincent T. K. Chow (109735), Yee Joo Tan (315572)   +6 more
core   +1 more source

Protective immune response against Rhodococcus equi: An innate immunity‐focused review

Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.
Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira, Noah D. Cohen, Sara D. Lawhon, Robert O. Watson, Angela I. Bordin   +4 more
wiley   +1 more source

Automated discovery and phylogenetic analysis of new toxin-antitoxin systems

BMC Microbiology, 2008
Background Although often viewed as elements "at the service of" bacteria, plasmids exhibit replication and maintenance mechanisms that make them purely "selfish DNA" candidates.
Milinkovitch Michel C, Szpirer Cédric, Guglielmini Julien   +2 more
doaj   +1 more source

Comparison of VAPC and VAPB-MSP.

, 2013
(a) Sequence alignment of the human 99-residue VAPC and 125-residue VAPB-MSP domain. The first 70 residues (in red) are completely identical, while the rest (in blue) are different in the two proteins.
Shaveta Goyal (315569), Haina Qin (143174), Garvita Gupta (158903), Megha Haridas Upadya (315570), Jianxing Song (143189), Vincent T. K. Chow (109735), Yee Joo Tan (315572)   +6 more
core   +1 more source

Disorganized thalamic subregional functional connectivity in bipolar I disorder

MedComm, Volume 5, Issue 11, November 2024.
FIGURE 1 Flowchart of inclusion and exclusion criteria, and resting‐state functional connectivity (FC) analysis of subcortical regions and thalamic subregions. A total of 151 participants were enrolled. All participants were scanned with high‐resolution MRI. After data collection, preprocessing and seed‐based FC analysis were then performed.
Xipeng Long, Xiuli Wang, Yuan Cao, Di Kong, Baolin Wu, Hongsheng Xie, Ziru Zhao, Neil Roberts, Qiyong Gong, Zhiyun Jia   +9 more
wiley   +1 more source

High‐quality genome of a novel Thermosynechococcaceae species from Namibia and characterization of its protein expression patterns at elevated temperatures

MicrobiologyOpen, Volume 13, Issue 5, October 2024.
In this study, the genome of a new thermophilic cyanobacterium, Thermosynechococcaceae cyanobacterium sp. Okahandja, isolated from a hot spring near Okahandja in Namibia, was sequenced. Additionally, cultivations were conducted at elevated temperatures of 40, 50, and 55°C, followed by analyses of the respective adapted proteomes based on the annotated ...
Nathanael D. Arnold, Michael Paper, Tobias Fuchs, Nadim Ahmad, Patrick Jung, Michael Lakatos, Katia Rodewald, Bernhard Rieger, Farah Qoura, Martha Kandawa‐Schulz, Norbert Mehlmer, Thomas B. Brück   +11 more
wiley   +1 more source

Toxin-antitoxin loci vapBC-1 and vapXD contribute to survival and virulence in nontypeable Haemophilus influenzae

BMC Microbiology, 2012
Background Nontypeable Haemophilus influenzae (NTHi) is a significant human pathogen responsible for respiratory tract infections and the most common cause of recurrent otitis media. Type II toxin-antitoxin (TA) systems are genetic elements that code for
Ren Dabin, Walker Anna N, Daines Dayle A
doaj   +1 more source

Binding between VAPC and NS5B.

, 2013
(a) Far-UV CD spectrum of HCV NS5B. (b) One-dimensional 1H NMR spectrum of HCV NS5B. Blue arrows are used to indicate very up-field NMR resonance peaks characteristic of a well-folded protein with tight tertiary packing. (c) Superimposition of 1H-15N NMR
Shaveta Goyal (315569), Haina Qin (143174), Garvita Gupta (158903), Megha Haridas Upadya (315570), Jianxing Song (143189), Vincent T. K. Chow (109735), Yee Joo Tan (315572)   +6 more
core   +1 more source

The Great Codon Escape: Vacating Codons for Genetic Code Expansion and Ribosome Stalling

Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.
Abstract In ribosomal synthesis of peptides and proteins, genetic information is translated into an amino acid polymer according to the genetic code, which describes the translational command encoded by each codon. However, parts of the genetic code can be adjusted to customize translations.
Antonius J. P. Hopstaken, Enno Große Wichtrup, Seino A. K. Jongkees   +2 more
wiley   +1 more source

3D model of leptospiral VapC closely matches the experimental X-ray structure of Shigella's VapC.

, 2014
Alignment of the sequences of VapCs from S. flexneri and L. interrogans is shown. On the left panel, the structure model (ribbon) of VapC from L. interrogans (green) was superimposed to the VapC template from S. flexneri (white) (PdB: 3TND-C).
André L. Sanson (602171), Luana M. Lopes (602169), Tatiana R. Fraga (476611), Elisabeth Cheng (602172), Rosa M. Chura-Chambi (602170), Alexandre P. Y. Lopes (602168), Erika Nakajima (602173), Ligia Morganti (602174), Elizabeth A. L. Martins (602175)   +8 more
core   +1 more source