Results 31 to 40 of about 1,032 (144)

Salmonella enterica serovar Cerro displays a phylogenetic structure and genomic features consistent with virulence attenuation and adaptation to cattle

open access: yesFrontiers in Microbiology, 2022
Salmonella enterica subsp. enterica (S.) serovar Cerro is rarely isolated from human clinical cases of salmonellosis but represents the most common serovar isolated from cattle without clinical signs of illness in the United States.
Alexa R. Cohn   +5 more
doaj   +1 more source

Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin

open access: yesmBio, 2023
A type II VapB14 antitoxin regulates biofilm dispersal in the archaeal thermoacidophile Sulfolobus acidocaldarius through traditional toxin neutralization but also through noncanonical transcriptional regulation.
April M. Lewis   +5 more
doaj   +1 more source

Mental development is associated with cortical connectivity of the ventral and nonspecific thalamus of preterm newborns

open access: yesBrain and Behavior, Volume 10, Issue 10, October 2020., 2020
Our purpose was to find a link between thalamocortical connectivity measures at term equivalent age and two‐year neurodevelopmental outcome in 58 infants following preterm birth. Using probabilistic diffusion tractography, we found that injury or dysmaturation of tracts emerging from ventral‐specific and various nonspecific thalamus projecting to late ...
Andras Jakab   +5 more
wiley   +1 more source

Regulation of the vapBC-1 toxin-antitoxin locus in nontypeable Haemophilus influenzae.

open access: yesPLoS ONE, 2012
Nontypeable Haemophilus influenzae (NTHi) are human-adapted commensal bacteria that can cause a number of chronic mucosal infections, including otitis media and bronchitis.
Susan D Cline   +2 more
doaj   +1 more source

Solution conformation of VAPC-43.

open access: yes, 2013
(a) Amino acid sequence of VAPC showing the sequences of truncated VAPC-43 (over residues 57–99) and VAPC-14 (72–85). Green arrows indicate four residues which were mutated into Ala in a VAPC-43 construct. (b) Far-UV CD spectrum of VAPC-43.
Shaveta Goyal (315569)   +6 more
core   +1 more source

Binding of VAPC-14 with NS5B.

open access: yes, 2013
(a) Far-UV CD spectrum of VAPC-14. (b) Superimposition of 1H-15N NMR HSQC spectra of VAPC-14 in the absence of (black) and in the presence of unlabeled NS5B at molar ratios of 0.5 (pink), 1∶1 (blue), and 1∶2.5 (green) (VAPC-14:NS5B).
Shaveta Goyal (315569)   +6 more
core   +1 more source

Solution conformation of VAPC.

open access: yes, 2013
(a) Far-UV CD spectra of VAPC at different pH values, i.e. 6.5 (green); 5.5 (purple); 4.5 (grey); 3.5 (cyan); 3.0 (red). (b) 1H-15N NMR HSQC spectrum of VAPC. The HSQC peaks for two Trp side chains are indicated by the red arrow.
Shaveta Goyal (315569)   +6 more
core   +1 more source

Evaluation of VapC models.

open access: yes, 2014
VapC structural models were evaluated by QMEAN4 and Z score in order to compare and rank alternative models of the same target. QMAN4 is a reliability score consisting of a combination of four structural descriptors which ranges between 0 and 1 with ...
André L. Sanson (602171)   +8 more
core   +1 more source

Binding of VAPC-43 with NS5B.

open access: yes, 2013
(a) Superimposition of 1H-15N NMR HSQC spectra of VAPC-43 in the absence of (blue) and in the presence of unlabeled NS5B at molar ratios of 1∶1 (green) and 1∶2.75 (red) (VAPC-43:NS5B).
Shaveta Goyal (315569)   +6 more
core   +1 more source

Predicting drug‐perturbed transcriptional responses using multi‐conditional diffusion transformer

open access: yesQuantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Drug‐perturbed transcriptomes are important for personalized medicine and drug discovery. Nevertheless, the existing high‐throughput screening and sequencing techniques for drug‐perturbed transcriptomes remain expensive and time‐consuming. In this study, we propose a novel multi‐condition diffusion transformer model, designated as perturbation
Qifan Hu, Zeyu Chen, Jin Gu
wiley   +1 more source

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