Results 31 to 40 of about 1,032 (144)
Salmonella enterica subsp. enterica (S.) serovar Cerro is rarely isolated from human clinical cases of salmonellosis but represents the most common serovar isolated from cattle without clinical signs of illness in the United States.
Alexa R. Cohn +5 more
doaj +1 more source
Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin
A type II VapB14 antitoxin regulates biofilm dispersal in the archaeal thermoacidophile Sulfolobus acidocaldarius through traditional toxin neutralization but also through noncanonical transcriptional regulation.
April M. Lewis +5 more
doaj +1 more source
Our purpose was to find a link between thalamocortical connectivity measures at term equivalent age and two‐year neurodevelopmental outcome in 58 infants following preterm birth. Using probabilistic diffusion tractography, we found that injury or dysmaturation of tracts emerging from ventral‐specific and various nonspecific thalamus projecting to late ...
Andras Jakab +5 more
wiley +1 more source
Regulation of the vapBC-1 toxin-antitoxin locus in nontypeable Haemophilus influenzae.
Nontypeable Haemophilus influenzae (NTHi) are human-adapted commensal bacteria that can cause a number of chronic mucosal infections, including otitis media and bronchitis.
Susan D Cline +2 more
doaj +1 more source
Solution conformation of VAPC-43.
(a) Amino acid sequence of VAPC showing the sequences of truncated VAPC-43 (over residues 57–99) and VAPC-14 (72–85). Green arrows indicate four residues which were mutated into Ala in a VAPC-43 construct. (b) Far-UV CD spectrum of VAPC-43.
Shaveta Goyal (315569) +6 more
core +1 more source
(a) Far-UV CD spectrum of VAPC-14. (b) Superimposition of 1H-15N NMR HSQC spectra of VAPC-14 in the absence of (black) and in the presence of unlabeled NS5B at molar ratios of 0.5 (pink), 1∶1 (blue), and 1∶2.5 (green) (VAPC-14:NS5B).
Shaveta Goyal (315569) +6 more
core +1 more source
Solution conformation of VAPC.
(a) Far-UV CD spectra of VAPC at different pH values, i.e. 6.5 (green); 5.5 (purple); 4.5 (grey); 3.5 (cyan); 3.0 (red). (b) 1H-15N NMR HSQC spectrum of VAPC. The HSQC peaks for two Trp side chains are indicated by the red arrow.
Shaveta Goyal (315569) +6 more
core +1 more source
VapC structural models were evaluated by QMEAN4 and Z score in order to compare and rank alternative models of the same target. QMAN4 is a reliability score consisting of a combination of four structural descriptors which ranges between 0 and 1 with ...
André L. Sanson (602171) +8 more
core +1 more source
(a) Superimposition of 1H-15N NMR HSQC spectra of VAPC-43 in the absence of (blue) and in the presence of unlabeled NS5B at molar ratios of 1∶1 (green) and 1∶2.75 (red) (VAPC-43:NS5B).
Shaveta Goyal (315569) +6 more
core +1 more source
Predicting drug‐perturbed transcriptional responses using multi‐conditional diffusion transformer
Abstract Drug‐perturbed transcriptomes are important for personalized medicine and drug discovery. Nevertheless, the existing high‐throughput screening and sequencing techniques for drug‐perturbed transcriptomes remain expensive and time‐consuming. In this study, we propose a novel multi‐condition diffusion transformer model, designated as perturbation
Qifan Hu, Zeyu Chen, Jin Gu
wiley +1 more source

