Results 21 to 30 of about 8,222 (211)

Safety and efficacy of RT234 vardenafil inhalation powder on exercise parameters in pulmonary arterial hypertension: phase II, dose-escalation study design

Respiratory Research, 2022
Background Pulmonary arterial hypertension (PAH) is a progressive disease characterized by high mean pulmonary arterial pressure (≥ 20 mmHg) and remodeling of the vascular arteries.
R. Benza, V. Franco, M. Aras, L. Spikes, D. Grinnan, C. Satler   +5 more
semanticscholar   +1 more source

Renoprotective Effect of Vardenafil and Avanafil in Contrast-Induced Nephropathy: Emerging Evidence from an Animal Model

Journal of Personalized Medicine, 2022
The potential renoprotective effects of vardenafil (VAR) have been evaluated in a very limited number of studies using acute kidney injury animal models other than contrast-induced nephropathy (CIN) with promising results, while avanafil (AVA) has not ...
I. Zisis, G. Georgiadis, A. Docea, D. Calina, Liliana Cercelaru, J. Tsiaoussis, G. Lazopoulos, N. Sofikitis, A. Tsatsakis, C. Mamoulakis   +9 more
semanticscholar   +1 more source

Survey on Sildenafil, Tadalafil, and Vardenafil Concentrations in Food Supplements for Erectile Dysfunction

International Journal of Analytical Chemistry, 2022
The aim of the study was to analyze the presence of undeclared sildenafil, tadalafil, and vardenafil in food supplements (FSs) for erectile dysfunction. The presence of sildenafil, tadalafil, and vardenafil was determined using the generated ultraviolet (
Elina S Petkova-Gueorguieva, S. Gueorguiev, H. Lebanova, V. Madzharov, Anna Mihaylova   +4 more
semanticscholar   +1 more source

Efficacy and safety of silodosin, vardenafil versus silodosin in combination with vardenafil as a medical expulsive therapy for distal ureteric stones: a prospective randomized double-blind study

African Journal of Urology, 2020
Background Urolithiasis is considered one of the most common diseases in urological practice. Its prevalence is about 1% to 15% with 30 years old as the peak age of incidence.
Mohamed Samir, Hossam Elawady, Mohamed Hasan   +2 more
doaj   +1 more source

Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells

Biology Open, 2020
Cystic fibrosis (CF) is a genetic disease characterized by progressive lung and chronic digestive manifestations. We have shown that therapeutic doses of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor, corrects CF Transmembrane conductance ...
Barbara Dhooghe, Caroline Bouzin, Angélique Mottais, Emmanuel Hermans, Martial Delion, Nadtha Panin, Sabrina Noel, Teresinha Leal   +7 more
doaj   +1 more source

HPLC-UV and UPLC-MS/MS methods for the simultaneous analysis of sildenafil, vardenafil, and tadalafil and their counterfeits dapoxetine, paroxetine, citalopram, tramadol, and yohimbine in aphrodisiac products

RSC Advances, 2021
In recent times, the counterfeiting of pharmaceuticals has been considered a serious trouble especially in developing countries that acquire poor inspection programs.
Mohamed A. Abdelshakour, Randa A Abdel Salam, Ghada M. Hadad, D. Abo-elmatty, Eman A. Abdel Hameed   +4 more
semanticscholar   +1 more source

Determination of Vardenafil in Human Plasma by LC/MS/MS and its Clinical Applications

Saudi Journal of Medical and Pharmaceutical Sciences, 2022
Background: Sexual dysfunction as a result of the inability to achieve or maintain an erection is a common problem that increases with age. Vardenafil has shown results as an efficacious and safe therapeutic agent for treatment of erectile dysfunction ...
Mohamed A. Raslan, E. M. S., S. R, N. Sabri   +3 more
semanticscholar   +1 more source

Development of vardenafil hydrochloride-loaded silica nanoparticles with enhanced transdermal delivery

Journal of Research in Pharmacy, 2022
: The aim of the present study was to develop a promising silica nanoparticle system to enhance the transdermal delivery of vardenafil hydrochloride (VRD) for treatment of erectile dysfunction. VRD-loaded silica nanoparticles were prepared using chitosan,
Hussein O. AMMAR, M. I. Tadros, Nahla M. Salama, A. Ghoneim   +3 more
semanticscholar   +1 more source

Vardenafil Reduces Testicular Damage Following Ischemia/Reperfusion Injury in Rats

Kaohsiung Journal of Medical Sciences, 2009
We investigated the effect of intraperitoneal vardenafil (1 mg/kg) administration during an ischemic period in a rat model of testicular torsion/detorsion (T/D). Twenty-one adult Wistar rats were equally randomized into a control group, a T/D group and a
Bulent Erol, Husnu Tokgoz, Volkan Hanci, Sibel Bektas, Bulent Akduman, Faruk Yencilek, Gorkem Mungan, Aydin Mungan   +7 more
doaj   +1 more source

Erectile dysfunction - an update of current practice and future strategies [PDF]

, 2013
Erectile dysfunction (ED) is defined as the inability to achieve and maintain a penile erection adequate for satisfactory sexual intercourse.1 Up to 150 million men worldwide suffer from ED and this figure is likely to double by the year 2025.2 A number
Kalsi, J, Muneer, A
core   +1 more source