Results 31 to 40 of about 3,797 (199)
Mitigating Effect of Vardenafil against Colchicine–Induced Testicular Toxicity in Adult Male Albino Rats Authors [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2016 Vardenafil is a phosphodiesterase-5 inhibitor, preserving and increasing the levels of cGMP (cyclic guanosine monophosphate) in soft muscle of the penis and increasing the erection duration.
Hasan El-Fakahany +2 more
doaj +1 more source
Heliyon, 2023 A novel vardenafil analogue was identified in dietary supplement as an adulterant in herbal formulations. The structure of this analogue was elucidated using HRMS, NMR after extraction from the pulverized powder.
Chunzheng Li +13 more
doaj +1 more source
Vardenafil Long-Term Administration Improves Episodic Memory in Aging Female Mice
Applied Sciences, 2023 Age-dependent cognitive decline is associated with a downregulation of the cyclic nucleotide cascade. Through their regulation of the cGMP pathway, phosphodiesterase 5 inhibitors have been proven to enhance episodic memory in rodents and mice and have ...
Harold Dadomo +4 more
doaj +1 more source
Erectile Dysfunction in Diabetes Mellitus: A Comprehensive Narrative Review of Pathophysiology, Genetic Association Studies and Therapeutic Approaches. [PDF]
Endocrinol Diabetes MetabInterplay between erectile dysfunction, diabetes mellitus and genetics. ABSTRACT Introduction Erectile dysfunction (ED) is a highly prevalent complication of diabetes mellitus (DM), significantly impairing quality of life and psychosocial well‐being. The prevalence of ED is estimated to be over 3.5 times higher in men with diabetes mellitus compared to
Hostnik B, Tonin G, Janež A, Klen J.
europepmc +2 more sources
Therapeutic potential of vardenafil in preventing sepsis-induced kidney injury: a preclinical study [PDF]
PharmaciaSepsis is caused by an infection-induced systemic inflammatory response that may lead to organ failure and death. This study aimed to evaluate the nephroprotective effect of vardenafil, a selective PDE-5 inhibitor, in preventing sepsis-induced kidney ...
Ghanim Al-ghanimi, Ali M. Janabi
doaj +3 more sources
Effects of vardenafil on the kidney of Wistar rats submitted to acute ischemia and reperfusion [PDF]
Acta Cirúrgica Brasileira, 2015 PURPOSE: To investigate the effect of vardenafil in kidney of rats submitted to acute ischemia and reperfusion.METHODS:Twenty-eight rats were randomly distributed into two groups.
Renato Chavasco de Sousa +4 more
doaj +1 more source
Medicina, 2023 Background and objectives: Taking into consideration the confirmed role of oxidative stress in ischemia/reperfusion injury and the insufficiency in knowledge regarding the phosphodiesterase 5 (PDE5)-mediated effects on the cardiovascular system, the aim ...
Milos Krivokapic +4 more
doaj +1 more source
A novel vardenafil analog in a healthcare product: Preparation, characterization, and quantification
Heliyon, 2023 Objective: This study is aimed to develop a qualitative and quantitative method to detect a novel vardenafil analogue from a healthcare product, which is claimed to enhance sexual function.
Jintao Xia +3 more
doaj +1 more source
P4.09 EFFECT OF VARDENAFIL ON ARTERIAL STIFFNESS AND WAVE REFLECTION
Artery Research, 2009 Introduction: While vardenafil is widely prescribed for erectile dysfunction, its effect on arterial function is not established. Arterial stiffness and wave reflections are markers of cardiovascular disease and predictors of cardiovascular risk.
D. Terentes-Printzios +6 more
doaj +1 more source
Antioxidants, 2021 Heart failure with preserved ejection fraction (HFpEF) and right ventricular (RV) dysfunction are frequent complications of diabetic cardiomyopathy. Here we aimed to characterize RV and left ventricular (LV) remodeling and its prevention by vardenafil (a
Beáta Bódi +10 more
doaj +1 more source