Results 21 to 30 of about 3,797 (199)

Erectile Dysfunction Drugs as Potential Therapy for Cognitive Decline: Preclinical and Translational Evidence [PDF]

open access: yesCells
Erectile dysfunction (ED) and cognitive decline share overlapping vascular, metabolic, and neurodegenerative mechanisms, particularly in aging populations.
Roberta Ricciarelli
doaj   +2 more sources

Membrane-Mediated Action of Phosphodiesterase 5 Inhibitors [PDF]

open access: yesPharmaceutics
Background/Objectives: Phosphodiesterase 5 (PDE5) inhibitors, sildenafil, vardenafil, and tadalafil, activate the cyclic guanosine monophosphate pathway resulting in vascular smooth muscle relaxation.
Anna I. Malykhina   +2 more
doaj   +2 more sources

Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence

open access: yesClinical Interventions in Aging, 2009
Antonio Martín Morales1, Vincenzo Mirone2, John Dean3, Pierre Costa41Department of Urology, Hospital Carlos Haya, Malaga, Spain; 2Department of Urology, University Federico II, Naples, Italy; 3St.
Antonio Martín Morales   +3 more
doaj   +2 more sources

Vardenafil Oral Dispersible Films (ODFs) with Advanced Dissolution, Palatability, and Bioavailability

open access: yesPharmaceutics, 2022
Oral, quick response, and on demand, also known as a spontaneous oral treatment for erectile dysfunction, is highly needed by both patients and physicians.
Heba A Abou-Taleb   +2 more
exaly   +3 more sources

Can Impaired Elasticity of Aorta Predict the Success of Vardenafil Treatment in Patients with Erectile Dysfunction?

open access: yesScientifica, 2016
Objective. Vardenafil is used in treatment of erectile dysfunction (ED) but reveals variable clinical outcomes. Here, we aimed to evaluate the role of aortic elasticity in predicting vardenafil success among patients with ED. Methods.
Hüseyin Ede   +8 more
doaj   +2 more sources

Ocular side effects of levitra® (vardenafil) – results of a double-blind crossover study in healthy male subjects

open access: yesDrug Design, Development and Therapy, 2018
Gernot Roessler, Michael Vobig, Peter Walter, Babac AE Mazinani Department of Ophthalmology, RWTH Aachen University, D-52057 Aachen, Germany Purpose: To determine ocular side effects of vardenafil with special regard to color vision and retinal ...
Roessler G   +3 more
doaj   +1 more source

Effect of Tramadol and Vardenafil Alone and in Combination on Adult Male Mice Reproductive Performance and Fertility [PDF]

open access: yesThe Egyptian Journal of Histology, 2023
Introduction: Tramadol is one of the most common analgesic drugs in chronic pain treatment. Their mechanism of action is through the inhibition of the noradrenaline and serotonin (5-HT) transmission reuptake.
Marwa Abd Al- Salam   +3 more
doaj   +1 more source

Sildenafil or Vardenafil Nonresponders’ Erectile Response to Tadalafil

open access: yesUrology Journal, 2009
Introduction: Erectile dysfunction has usually been treated by a phosphodiesterase 5 inhibitor in men, especially in the past decade. Although sildenafil and vardenafil are widely used, there is a high percentage of people who do not respond to these ...
Berat Cem Ozgur   +2 more
doaj   +2 more sources

High Dose Vardenafil Blunts the Hypertensive Effects of Toll-Like Receptor 3 Activation During Pregnancy

open access: yesFrontiers in Virology, 2021
The maternal innate immune system plays a central role in preeclampsia (PE). Toll-like receptors (TLRs) are innate immune system receptors that recognize characteristics of extracellular endogenous ligands or pathogens, and their activation leads to a ...
Dakshnapriya Balasubbramanian   +5 more
doaj   +1 more source

Efficacy and safety of silodosin, vardenafil versus silodosin in combination with vardenafil as a medical expulsive therapy for distal ureteric stones: a prospective randomized double-blind study

open access: yesAfrican Journal of Urology, 2020
Background Urolithiasis is considered one of the most common diseases in urological practice. Its prevalence is about 1% to 15% with 30 years old as the peak age of incidence.
Mohamed Samir   +2 more
doaj   +1 more source

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