Results 131 to 140 of about 3,116,070 (323)

On the Testability of Causal Models with Latent and Instrumental Variables [PDF]

arXiv, 2013
Certain causal models involving unmeasured variables induce no independence constraints among the observed variables but imply, nevertheless, inequality contraints on the observed distribution. This paper derives a general formula for such instrumental variables, that is, exogenous variables that directly affect some variables but not all.
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Dynamic deep learning based super-resolution for the shallow water equations

Machine Learning: Science and Technology
Correctly capturing the transition to turbulence in a barotropic instability requires fine spatial resolution. To reduce computational cost, we propose a dynamic super-resolution approach where a transient simulation on a coarse mesh is frequently ...
Maximilian Witte, Fabrício R Lapolli, Philip Freese, Sebastian Götschel, Daniel Ruprecht, Peter Korn, Christopher Kadow   +6 more
doaj   +1 more source

Studies in the evolution of Pecten IV. Ray variability in Pecten varius [PDF]

, 1904
C. B. Davenport, Marian E. Hubbard
openalex   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

I. Variability, Symmetry and Fertility In an abnormal Speoies [PDF]

, 1902
C. B. Davenport
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Variability in the level of attachment of the lower limb to the vertebral axis in man [PDF]

, 1891
Ambrose Birmingham
openalex   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Types of Dysentery Bacilli isolated at No. 3 Australian General Hospital, Cairo, March—August, 1916, with Observations on the Variability of the Mannite Fermenting Group [PDF]

, 1917
Claire Martin, Fred Williams
openalex   +1 more source