Results 101 to 110 of about 3,212,271 (295)

Simple Elliptic Singularities: a note on their G-function

, 2011
The link between Frobenius manifolds and singularity theory is well known, with the simplest examples coming from the simple hypersurface singularities. Associated with any such manifold is a function known as the $G$-function.
Strachan, I. A. B.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A Soluble Model for Scattering and Decay in Quaternionic Quantum Mechanics I: Decay

, 1993
The Lee-Friedrichs model has been very useful in the study of decay-scattering systems in the framework of complex quantum mechanics. Since it is exactly soluble, the analytic structure of the amplitudes can be explicitly studied.
Horwitz, L. P.
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Variable Structure Systems and Systems Zeros

, 1981
The analysis of variable structure systems in the sliding mode yields the concept of equivalent control which leads naturally to a new method for determining the zeros and zero directions of linear multivariable systems. The analysis presented is conceptually easy and computationally attractive.
El-Ghezawi, O.M.E., Billings, S.A., Zinober, A. S. I.   +2 more
openaire  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Output Feedback Variable Structure Control Design for Uncertain Nonlinear Lipschitz Systems

Journal of Control Science and Engineering, 2015
This paper develops a full-order compensator-based output feedback variable structure control law for uncertain nonlinear Lipschitz systems having matched perturbations. Given that the sufficient condition is satisfied, the developed control scheme, with
Jeang-Lin Chang, Tsui-Chou Wu
doaj   +1 more source

Physics-inspired Performace Evaluation of a Structured Peer-to-Peer Overlay Network [PDF]

, 2005
In the majority of structured peer-to-peer overlay networks a graph with a desirable topology is constructed. In most cases, the graph is maintained by a periodic activity performed by each node in the graph to preserve the desirable structure in face
Aurell, Erik, El-Ansary, Sameh, Haridi, Seif   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source