Results 81 to 90 of about 17,447,143 (292)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Variable structure systems theory in computational intelligence
, 2002 Intelligence in the form of well-organized solutions to the ill-posed problems has been the primary focus of many engineering applications. The eve-rincreasing developments in data fusion, sensor technology and high-speed microprocessors made the design ...
Yu, Xing Huo. +5 more
core
Schematization and Dynamic Analysis of Mobile Machine. Variable-Structure Systems.
Механика машин, механизмов и материалов, 2008 Approaches for modeling the complex mechanical systems of mobile machines are discussed. Basic definitions related to schematization and dynamic analyses of mechanical systems are justified.
V.B. Algin +3 more
doaj
Friction compensation of servo system based on terminal switching function
The Journal of Engineering, 2013 Based on the LuGre friction model, a sliding mode adaptive controller is presented to compensate for the friction in the servo system. The terminal switching function is selected as the sliding mode surface, which can make the error of the system ...
Xue Lin, Zhonghua Wang
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Structure Theory for Extended Kepler-Coulomb 3D Classical Superintegrable Systems [PDF]
, 2012 The classical Kepler-Coulomb system in 3 dimensions is well known to be 2nd order superintegrable, with a symmetry algebra that closes polynomially under Poisson brackets. This polynomial closure is typical for 2nd order superintegrable systems in 2D and
Willard Miller Jr. +5 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Variable structure systems for control of redundant robot
Robotics and Autonomous Systems, 1994 Abstract A combination of one class of kinematic control of redundant robot and Variable Structure Systems (VSS) in manipulating tasks that require large accelerations or decelerations is the main issue of this paper. The inverse kinematic problem will, on a tactical control level, be solved through Distributed Positioning (DP) concept, while the ...
Veljko Potkonjak +4 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source