Results 31 to 40 of about 8,438 (230)

Transcript expression analysis of putative Trypanosoma brucei GPI-anchored surface proteins during development in the tsetse and mammalian hosts. [PDF]

PLoS Neglected Tropical Diseases, 2012
Human African Trypanosomiasis is a devastating disease caused by the parasite Trypanosoma brucei. Trypanosomes live extracellularly in both the tsetse fly and the mammal.
Amy F Savage, Gustavo C Cerqueira, Sandesh Regmi, Yineng Wu, Najib M El Sayed, Serap Aksoy   +5 more
doaj   +1 more source

The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice. [PDF]

PLoS Pathogens, 2008
African trypanosomes are extracellular parasitic protozoa, predominantly transmitted by the bite of the haematophagic tsetse fly. The main mechanism considered to mediate parasitemia control in a mammalian host is the continuous interaction between ...
Stefan Magez, Anita Schwegmann, Robert Atkinson, Filip Claes, Michael Drennan, Patrick De Baetselier, Frank Brombacher   +6 more
doaj   +1 more source

Structural characterization of the asparagine-linked oligosaccharides from Trypanosoma brucei type II and type III variant surface glycoproteins.

Journal of Biological Chemistry, 1991
The complete primary structures of the major Asn-linked oligosaccharides from the type II variant surface glycoproteins (VSGs), MITat 1.2 and MITat 1.7, and the type III VSG, MITat 1.5, were determined using a combination of exo- and endoglycosidase ...
S. Zamze, David A. Ashford, E. W. Wooten, T. Rademacher, Anthony J. Rossomnndo, S. L. Pelech   +5 more
semanticscholar   +1 more source

Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei.

PLoS Pathogens, 2012
The transferrin receptor of bloodstream form Trypanosoma brucei is a heterodimer encoded by expression site associated genes 6 and 7. This low-abundance glycoprotein with a single glycosylphosphatidylinositol membrane anchor and eight potential N ...
Angela Mehlert, Mark R Wormald, Michael A J Ferguson   +2 more
doaj   +1 more source

Biosynthesis of SUMOylated Proteins in Bacteria Using the Trypanosoma brucei Enzymatic System. [PDF]

PLoS ONE, 2015
Post-translational modification with the Small Ubiquitin-like Modifier (SUMO) is conserved in eukaryotic organisms and plays important regulatory roles in proteins affecting diverse cellular processes. In Trypanosoma brucei, member of one of the earliest
Paula Ana Iribarren, María Agustina Berazategui, Juan José Cazzulo, Vanina Eder Alvarez   +3 more
doaj   +1 more source

The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]

, 2019
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K., Magez, Stefan, Stijlemans, Benoit   +2 more
core   +2 more sources

Single-subunit oligosaccharyltransferases of Trypanosoma brucei display different and predictable peptide acceptor specificities [PDF]

, 2017
Trypanosoma brucei causes African trypanosomiasis and contains three full-length oligosaccharyltransferase (OST) genes; two of which, TbSTT3A and TbSTT3B, are expressed in the bloodstream form of the parasite.
Abraham, Acosta-Serrano, Acosta-Serrano, Aebi, Allison, Anders Jinnelov, Aslett, Atrih, Bandini, Bangs, Bangs, Boehm, Brandes, Butter, Cardoso de Almeida, Castillo-Acosta, Castillo-Acosta, Castillo-Acosta, Castro, Cherepanova, Cherepanova, Choi, Crooks, Damerow, Damerow, Engstler, Ferguson, Ferguson, Güther, Güther, Hese, Hirumi, Horn, Izquierdo, Izquierdo, Izquierdo, Jackson, Jones, Kalb, Kelleher, Kelley, Krissinel, LaCount, Liaqat Ali, Lingnau, Lizak, Maishman, Manthri, Maria Lucia S. Güther, Mehlert, Mehlert, Michael A.J. Ferguson, Michele Tinti, Miller, Mohorko, Nagamune, Nasab, Oberholzer, Peck, Pettersen, Poljak, Ruiz-Canada, Salmon, Schulz, Schwede, Shrimal, Siegel, Steverding, Tiengwe, Treumann, Urbaniak, Urbaniak, Vacic, Wirtz, Woycechowsky, Yan, Zamze, Zamze, Zielinska   +78 more
core   +3 more sources

An extensive endoplasmic reticulum-localised glycoprotein family in trypanosomatids [PDF]

, 2014
Peer reviewedPublisher ...
Allison, Harriet, Field, Mark C, O'Reilly, Amanda J, Sternberg, Jeremy M   +3 more
core   +20 more sources

A gene of the β3-glycosyltransferase family encodes N-acetylglucosaminyltransferase II function in Trypanosoma brucei [PDF]

, 2016
The bloodstream form of the human pathogen Trypanosoma brucei expresses oligomannose, paucimannose and complex N-linked glycans, including some exceptionally large poly-N-acetyllactosamine-containing ...
Acosta-Serrano, Alexander, Atrih, Bendiak, Cross, Cross, Cross, Damerow, Ferguson, Ferguson, Ferguson, Ferguson, Geisler, Giraudo, Güther, Horn, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Jaeken, Lombard, Manthri, Mariño, Mehlert, Mehlert, Mehlert, Mehlert, Mehlert, Milne, Nakanishi, Narimatsu, Pays, Roper, Roper, Schachter, Schachter, Sevova, Sonnhammer, Steverding, Steverding, Stokes, Sutterwala, Urbaniak, Urbaniak, Urbaniak, Wang, Wiggins, Wirtz, Zamze, Zamze, Ziegelbauer   +51 more
core   +2 more sources

Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei [PDF]

, 2020
BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles.
Hide, G, Lai, D-H, Li, F-J, Lun, Z-R, Xu, Z-S   +4 more
core   +2 more sources