Results 71 to 80 of about 4,234 (154)

Variant surface glycoproteins from Venezuelan trypanosome isolates are recognized by sera from animals infected with either Trypanosoma evansi or Trypanosoma vivax [PDF]

, 2014
Salivarian trypanosomes sequentially express only one variant surface glycoprotein (VSG) on their cell surface from a large repertoire of VSG genes. Seven cryopreserved animal trypanosome isolates known as TeAp-ElFrio01, TEVA1 (or TeAp-N/D1), TeGu-N/D1 ...
Acosta Serrano, Alvaro
core   +1 more source

Hidden Markov Models for Gene Sequence Classification: Classifying the VSG genes in the Trypanosoma brucei Genome

, 2015
The article presents an application of Hidden Markov Models (HMMs) for pattern recognition on genome sequences. We apply HMM for identifying genes encoding the Variant Surface Glycoprotein (VSG) in the genomes of Trypanosoma brucei (T.
Alvarez-Valin, Fernando, Basterrech, Sebastián, Guerberoff, Gustavo, Mesa, Andrea   +3 more
core   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Transcriptomic analysis of N-terminal mutated Trypanosoma cruzi UBP1 knockdown underlines the importance of this RNA-binding protein in parasite development.

PLoS Neglected Tropical Diseases
BackgroundDuring its life cycle, the human pathogen Trypanosoma cruzi must quickly adapt to different environments, in which the variation in the gene expression of the regulatory U-rich RNA-binding protein 1 (TcUBP1) plays a crucial role.
Karina B Sabalette, Vanina A Campo, José R Sotelo-Silveira, Pablo Smircich, Javier G De Gaudenzi   +4 more
doaj   +1 more source

Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei:the ethanolamine and choline kinases [PDF]

, 2008
Note related output below contains correction of this paper.Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (glycero-phosphoethanolamine) and GPCho (glycerophosphocholine).
Ayoama, Baba, Bürgemaister, Chang, Choubey, Clary, Cuadrado, Dowhan, Federica Gibellini, Ferguson, Gee, Imhof, Kennedy, Kim, Kim, Malito, Menon, Menon, Nagamune, Patnaik, Peisach, Rifkin, Scheef, Smith, Terry K. Smith, Urbina, Wharfe, William N. Hunter, Yuan   +28 more
core   +8 more sources

SUMOylated SNF2PH promotes variant surface glycoprotein expression in bloodstream trypanosomes [PDF]

, 2019
SUMOylation is a post¿translational modification that positively regulates monoallelic expression of the trypanosome variant surface glycoprotein (VSG).
Alvarez, Vanina E., Andrés-León, Eduardo, Bart, Jean M., Boehm, Cordula, Field, Mark C., Iribarren, Paula A., López-Farfán, Diana, Navarro, Miguel, Rojas-Barros, Domingo, Saura, Andreu, Vidal-Cobo, Isabel   +10 more
core   +5 more sources

Untersuchungen zur Topologie der Glycosylphosphatidylinositol-Biosynthese in Toxoplasma gondii [PDF]

, 2004
Toxoplasma gondii ist ein obligat intrazellulär lebendes, parasitisches Protozoon mit großer medizinischer Bedeutung vor allem in zwei Fällen: Zum einen bei Erstinfektion während einer Schwangerschaft, hier kann es zur Schädigung des Fötus kommen, zum ...
Kimmel, Jürgen, Lingelbach, Klaus (Prof. Dr.)   +1 more
core   +1 more source

Developmentally regulated instability of the GPI-PLC mRNA is dependent on a short-lived protein factor. [PDF]

, 2005
The expression of the vast majority of protein coding genes in trypanosomes is regulated exclusively at the post-transcriptional level. Developmentally regulated mRNAs that vary in levels of expression have provided an insight into one mechanism of ...
Burns, Roisin, Carrington, Mark, Ellis, Louise, Kimblin, Nicola, Webb, Helena   +4 more
core   +2 more sources

The interaction of Trypanosoma congolense with endothelial cells [PDF]

, 2017
Factors which affect adhesion of cultured Trypanosoma congolense bloodstream forms to mammalian feeder cells have been examined. Using an in vitro binding assay, the initial events following interaction of trypanosomes with bovine aorta endothelial (BAE)
Frame, I., Hemphill, A., Ross, C. A.
core  

The genetics and genomics of Trypanosoma cruzi [PDF]

, 2007
Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes are unusual organisms in many aspects of its genetics and molecular and cellular biology and considered a paradigm of the exception of the rule in the eukaryotic ...
Vazquez, Martin Pablo
core