Results 111 to 120 of about 619,919 (307)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Lower bounds for the normalized height and non-dense subsets of varieties in an abelian variety [PDF]
, 2010 This work is the third part of a series of papers. In the first two we considered curves and varieties in a power of an elliptic curve. Here we deal with subvarieties of an abelian variety in general.
Viada, Evelina
core +1 more source
Dwarfing Effects of Plant Growth Regulators on Banana Plants
Guangdong nongye kexue【Objective】The study was conducted to screen plant growth regulators that could shorten the plant height of banana without affecting the yield, and explore the dwarfing effects of their application times on banana plants.
Liuyan QIN +7 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
PlantsTrichomes are specialized organs located in the plant epidermis that play important defense roles against biotic and abiotic stresses. However, the mechanisms regulating the development of pepper epidermal trichomes and the related regulatory genes at ...
Yiyu Shen +7 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2012 Sicily is an island to the south and west of Italy that is close to the “toe of the boot”, in the Mediterranean Sea. Its physical characteristics are representative of the Mediterranean region with its mountainous terrain and volcanoes, rugged coast ...
PISCIOTTA, Antonino
core
Hop Breeding in the Czech Republic.
Kvasný průmysl, 2012 Hop breeding objectives in CR can be divided into aroma and bitter hops, both being resistant to stresses, dwarf varieties for cultivation in low trellis and varieties for pharmaceutical utilization.
Vladimír NESVADBA +2 more
doaj +1 more source