Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
From Stages to Varieties of Capitalism: Lessons, Limits and Prospects [PDF]
The basic aim of this paper is to take a tour de force in order to put the varieties of capitalism (VoC) approach in perspective and to assess its limits and further prospects.
Utku Havuç +2 more
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Evgeny P. Ilyin’s views on communication and their importance for the educational process
Communication is a complex, holistic, and multifaceted process that is unique to humans alone. It is based on establishing mental contact between real and directly interacting individuals to express their inner world (ideas, feelings, thoughts, needs ...
Stoyko Ivanov
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Alabama Performance Comparison of Peanut Varieties 2014 [PDF]
Caption title.
Bostick, James P. +2 more
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UJI ADAPTASI BEBERAPA VARIETAS SORGUM MANIS DI LAHAN KERING WILAYAH JAWA TENGAH DAN JAWA TIMUR
The research was conducted from May to November 2011 at Central Java (Karanganyar District) and East Java (ngawi district) dry land. The research was used Randomized Complete Block Design (RCBD) and with two treatments, were: sweet sorghum varieties ...
Muji Rahayu +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Performance of small grain varieties for grain in Alabama, 2005 [PDF]
Caption title: 2004 [sic: 2005] Alabama Performance Comparison of Small Grain Varieties. Cover title: Performance of small grain varieties for grain in Alabama, 2005. "August 2005.
Van Santen, Edzard +2 more
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Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
BACKGROUND TO THE INTRODUCTION OF HIGH YIELDING VARIETIES OF RICE IN THAILAND [PDF]
This paper describes Thailand's experience to date with new technology in rice, namely new high yielding varieties with associated inputs, which forms one part of the "green revolution." First, the historical background in exports, production, and ...
Welsch, Delane E., Tongpan, Sopin
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