Results 121 to 130 of about 1,388,843 (289)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Secant varieties of toric varieties
v1, AMS LaTex, 5 figures, 25 pages; v2, reference added; v3, This is a major rewrite. We have strengthened our main results to include a classification of smooth lattice polytopes P such that Sec X_P does not have the expected dimension. (See Theorems 1.4 and 1.5.) There was also a considerable amount of reorganization, and some expository material was
Cox, David, Sidman, Jessica
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Oat Variety Test, Triticale Variety Test, Barley Variety Test
Includes: Oat Variety Test Triticale Variety Test Barley Variety ...
Skrdla, Ronald, Jannink, Jean-Luc
openaire +3 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The present study for the first time tested the effect of repeated mild air exposure stress (RMS, 150 min) every four days on the growth, survival rate after acute air exposure, and relative pathways in female and male green mud crab (Scylla paramamosain)
Noah Esmaeili +7 more
doaj +1 more source
The minimum and maximum number of rational points on jacobian surfaces over finite fields
We give some bounds on the numbers of rational points on abelian varieties and jacobians varieties over finite fields. The main result is that we determine the maximum and minimum number of rational points on jacobians varieties of dimension ...
Haloui, Safia
core +2 more sources

