Results 101 to 110 of about 12,414 (226)

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice.

open access: yesPLoS Pathogens, 2015
Orthopoxviruses (OPV), including variola, vaccinia, monkeypox, cowpox and ectromelia viruses cause acute infections in their hosts. With the exception of variola virus (VARV), the etiological agent of smallpox, other OPV have been reported to persist in ...
Isaac G Sakala   +6 more
doaj   +1 more source

Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

open access: yesViruses, 2016
In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox.
Jennifer Garver   +7 more
doaj   +1 more source

Bibliography on inactivation of viruses and rickettsiae by heat [PDF]

open access: yes
Inactivation of viruses and rickettsiae by heat ...
Homann, L. M., Watson, M. S.
core   +1 more source

Genomic analysis of vaccinia virus strain TianTan provides new insights into the evolution and evolutionary relationships between Orthopoxviruses [PDF]

open access: yes, 2013
Vaccinia virus (VACV) strain TianTan was used for much of China's modern history to vaccinate against smallpox, however the only genome sequence contains errors.
Evans, David H., Liang, Min, Qin, Li
core   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 16, 23 June, 2025.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling   +4 more
wiley   +1 more source

Susceptible‐infected‐recovered model with stochastic transmission

open access: yesCanadian Journal of Statistics, Volume 53, Issue 2, June 2025.
Abstract The susceptible‐infected‐recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which results in its lack of flexibility and explains its difficulty to replicate the volatile reproduction numbers observed in practice.
Christian Gouriéroux, Yang Lu
wiley   +1 more source

A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus

open access: yesmSphere, 2018
This article evaluates the scientific and commercial rationales for the synthesis of horsepox virus. I find that the claimed benefits of using horsepox virus as a smallpox vaccine rest on a weak scientific foundation and an even weaker business case that
Gregory D. Koblentz
doaj   +1 more source

Smallpox in the Post-Eradication Era

open access: yesViruses, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer   +2 more
doaj   +1 more source

Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence. [PDF]

open access: yes, 2007
Camelpox virus (CMLV) gene 176R encodes a protein with sequence similarity to murine schlafen (m-slfn) proteins. In vivo, short and long members of the m-slfn family inhibited T-cell development, whereas in vitro, only short m-slfns caused arrest of ...
Brady, Gareth   +6 more
core   +2 more sources

Poxvirus Viability and Signatures in Historical Relics

open access: yesEmerging Infectious Diseases, 2014
Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence ...
Andrea M. McCollum   +7 more
doaj   +1 more source

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