Results 111 to 120 of about 14,974 (222)

Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

open access: yesViruses, 2016
In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox.
Jennifer Garver   +7 more
doaj   +1 more source

Topography of Variola Smallpox Virus Inverted Terminal Repeats

open access: yesVirology, 1995
We examined the nucleotide sequences of the inverted terminal repeat (ITR) regions adjacent to the covalently closed hairpin end sequences of three variola major and four minor strains from smallpox outbreaks in Europe, Asia, Africa, and South America.
Massung, Robert F.   +2 more
openaire   +2 more sources

In Silico Studies of Potential Selective Inhibitors of Thymidylate Kinase from Variola virus. [PDF]

open access: yesPharmaceuticals (Basel), 2021
Garcia DR   +7 more
europepmc   +1 more source

Poxvirus Viability and Signatures in Historical Relics

open access: yesEmerging Infectious Diseases, 2014
Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence ...
Andrea M. McCollum   +7 more
doaj   +1 more source

Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus. [PDF]

open access: yesPLoS Pathog, 2021
Hutson CL   +13 more
europepmc   +1 more source

A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus

open access: yesmSphere, 2018
This article evaluates the scientific and commercial rationales for the synthesis of horsepox virus. I find that the claimed benefits of using horsepox virus as a smallpox vaccine rest on a weak scientific foundation and an even weaker business case that
Gregory D. Koblentz
doaj   +1 more source

Comparative analysis of the complete genome sequence of the California MSW strain of myxoma virus reveals potential host adaptations

open access: yes, 2015
Myxomatosis is a rapidly lethal disease of European rabbits that is caused by myxoma virus (MYXV). The introduction of a South American strain of MYXV into the European rabbit population of Australia is the classic case of host-pathogen coevolution ...
Cattadori, Isabella M   +8 more
core   +1 more source

Reindeer Parapoxvirus [PDF]

open access: yes, 2012
Parapoxviruses (PPVs) are zoonotic viruses which cause contagious pustular skin infections of sheep, goats and cattle worldwide. In addition, they have more recently been shown to infect other animals such as red deer, seals, camels and reindeer ...
Hautaniemi, Maria
core  

Biological threat preparedness through vaccine development and stockpiling: challenges and strategic implications

open access: yesFrontiers in Public Health
Biological threat agents such as Bacillus anthracis, Variola virus, and botulinum toxin pose serious risk to national security and public health due to their high transmissibility, lethality, and potential for weaponization.
Jungeun Lee
doaj   +1 more source

Perioral Molluscum Contagiosum- Report of 2 Cases in HIV Seropositive Patients

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2007
Molluscum contagiosum (MC) is a mucocutaneous disorder caused by DNA virus of the Pox family affecting both the children and adults. MCV remains by far the most common pox viral pathogen for humans after the eradication of Small pox variola virus (1 ...
K T Magesh, N Malathi, S Anandan
doaj  

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