Results 91 to 100 of about 1,474,592 (383)
Iron and vascular calcification. Is there a link? [PDF]
Nephrology Dialysis Transplantation, 2011 Iron deficiency is frequently seen in patients with end-stage renal disease, particularly in those treated by dialysis, this is because of an impairment in gastrointestinal absorption and ongoing blood losses or alternatively, due to an impaired capacity to mobilize iron from its stores, called functional iron deficiency.
Neven, Ellen +4 more
openaire +4 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2022 ObjectiveTo explore the relationship between serum levels of miR-129 and miR-205 and vascular calcification in non-dialysis patients with chronic kidney disease （CKD）.MethodsFrom June 2020 to January 2021，54 CKD inpatients were selected as research ...
He Lei +7 more
doaj
Mild and moderate pre-dialysis chronic kidney disease is associated with increased coronary artery calcium. [PDF]
, 2011 BackgroundIt is increasingly evident that patients with chronic kidney disease (CKD) are more likely to die from heart disease than kidney failure. This study evaluated whether pre- dialysis CKD is an independent risk factor for coronary artery calcium ...
Budoff, Matthew J +4 more
core +2 more sources
Bioengineering, 2020 Characterized by the hardening of arteries, vascular calcification is the deposition of hydroxyapatite crystals in the arterial tissue. Calcification is now understood to be a cell-regulated process involving the phenotypic transition of vascular smooth ...
J. Tyson +7 more
semanticscholar +1 more source
Vascular calcification: Mechanisms of vascular smooth muscle cell calcification [PDF]
Trends in Cardiovascular Medicine, 2015 Vascular calcification is highly prevalent and, when present, is associated with major adverse cardiovascular events. Vascular smooth muscle cells play an integral role in mediating vessel calcification by undergoing differentiation to osteoblast-like cells and generating matrix vesicles that serve as a nidus for calcium-phosphate deposition in the ...
openaire +3 more sources
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Vascular Calcification: Current Genetics Underlying This Complex Phenomenon
Chinese Medical Journal, 2017 Objective: Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima (atherosclerotic calcification) or tunica media (
Nonanzit Pérez-Hernández +7 more
doaj +1 more source
Renal Failure, 2022 Chronic kidney disease (CKD) has recently become a serious health and social concern. Vascular calcification, a common complication of CKD, is a risk factor that increases the incidence and mortality of cardiovascular events in patients with CKD. However,
Qiong Xiao +10 more
doaj +1 more source
The connections between vascular calcification and bone health [PDF]
, 2013 Vascular calcification, bone loss and increased fracture risk are age-associated disorders. Several epidemiological studies have suggested a relationship between vascular calcification, impaired bone metabolism and increased mortality.
Cannata, J.B. (Jorge) +2 more
core