Results 91 to 100 of about 126,547 (360)

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

Relationship between Vascular Calcification, Protein-Energy Wasting Syndrome, and Sarcopenia in Maintenance Automated Peritoneal Dialysis

Life, 2021
Vascular calcifications affect 80% to 90% of chronic kidney disease patients and are a predictive factor of cardiovascular mortality. Sarcopenia and protein-energy wasting syndrome are also associated with mortality.
Gustavo Leal-Alegre, Claudia Lerma, Gabriela Leal-Escobar, Bernardo Moguel-González, Karen Belén Martínez-Vázquez, Karla Berenice Cano-Escobar   +5 more
doaj   +1 more source

TSA-inspired micro tomosythesis scanner for rapid scouting of histopathology samples [PDF]

arXiv, 2020
In pathology protocols, each tissue block can generate a large number of sections making it impractical to analyze every section. X-ray microscopy that provides a rapid survey of intact tissue blocks can help pinpoint the relevant structures in 3D space for subsequent analysis, and thus reduce workload and enable further automation downstream.
arxiv  

Downregulated serum 14, 15-epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism [PDF]

, 2018
Patients with primary aldosteronism (PA) have increased risk of target-organ damage, among which vascular calcification is an important indicator of cardiovascular mortality.
Gao, Jingwei, He, Wanbing, Huang, Hui, Lin, Ying, Liu, Pinming, Shi, Guangzi, Touyz, Rhian M., Yan, Li, Zhang, Shaoling   +8 more
core   +1 more source

Microglia control small vessel calcification via TREM2. [PDF]

, 2021
Microglia participate in central nervous system (CNS) development and homeostasis and are often implicated in modulating disease processes. However, less is known about the role of microglia in the biology of the neurovascular unit (NVU).
Colonna, M., Delorenzi, M., Greter, M., Keller, A., Maheshwari, U., Nassiri, S., Nilsson, KPR, Rushing, E.J., Schaffenrath, J., Sridhar, S., Utz, S.G., Zarb, Y.   +11 more
core   +2 more sources

Extensive vascular calcification

Indian Journal of Health Sciences and Biomedical Research (KLEU), 2015
Calciphylaxis denotes the presence of cutaneous gangrene secondary to the ischemic necrosis caused by vascular calcification. This is seen in patients with end stage renal disease, especially those using the renal replacement therapy. We recently encountered an elderly patient with long standing type 2 diabetes who presented with diabetic foot disease.
Mukesh Dhillon, K. V. S. Hari Kumar, Vipin Kwatra, Saurabh Dawra   +3 more
openaire   +3 more sources

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

The connections between vascular calcification and bone health [PDF]

, 2013
Vascular calcification, bone loss and increased fracture risk are age-associated disorders. Several epidemiological studies have suggested a relationship between vascular calcification, impaired bone metabolism and increased mortality.
Cannata, J.B. (Jorge), Hruska, Keith, Román-García, Pablo   +2 more
core  

Association of serum fetuin-A and biochemical parameters in hemodialysis patients. [PDF]

, 2014
Fetuin-A, a hepatic glycoprotein present in the circulation, is a potential inhibitor for systemic calcification. The main aim of this study was to evaluate the association between fetuin-A and other biochemical parameters as facilitator factors for ...
Besharat, S., Farajollahi, M., Haddad, M., Joshaghani, H.R., Qorbani, M., Tajbakhsh, R.   +5 more
core   +2 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source