Results 101 to 110 of about 10,815,340 (358)

Slovenian recommendations for the detection and treatment of venous thrombosis

Zdravniški Vestnik, 2016
 * no ...
Matija Kozak, Monika Štalc, Mateja Kaja Ježovnik, Mišo Šabovič, Alenka Mavri, Ivan Žuran, Aleš Blinc, Tjaša Vižintin Cuderman   +7 more
doaj  

European Reference Network For Rare Vascular Diseases (VASCERN) Outcome Measures For Hereditary Haemorrhagic Telangiectasia (HHT)

Orphanet Journal of Rare Diseases, 2018
Hereditary haemorrhagic telangiectasia (HHT) is a multisystemic vascular dysplasia that leads to nosebleeds, anaemia due to blood loss, and arteriovenous malformations (AVMs) in organs such as the lungs, liver and brain. HHT is estimated to affect 85,000
C. Shovlin, E. Buscarini, A. Kjeldsen, H. Mager, C. Sabbà, F. Droege, U. Geisthoff, S. Ugolini, S. Dupuis-Girod   +8 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Liver resections: complications and survival outcome [PDF]

, 2007
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core   +1 more source

Comparisons of outcomes of open surgery versus endovascular intervention for thrombotic popliteal artery aneurysm with acute lower limb ischemia: a systematic review

BMC Surgery, 2022
Background Thrombotic popliteal artery aneurysm (PAA) with acute lower limb ischemia (ALI) is a serious disease leading to amputation. The choice of emergency procedures is not clearly defined, and the difference in therapeutic efficiency between open ...
Xixi Xiao, Ruijia Feng, Mingshan Wang, Hanqi Sun, Tianzhen Jing, Lianhua Su, You Fan, Zuojun Hu, Shenming Wang, Siwen Wang   +9 more
doaj   +1 more source

Epigenetic Regulation of Vascular Diseases.

Arteriosclerosis, Thrombosis and Vascular Biology, 2019
Epigenetic regulatory mechanisms, encompassing diverse molecular processes including DNA methylation, histone post-translational modifications, and noncoding RNAs, are essential to numerous processes such as cell differentiation, growth and development ...
Abdalrahman Zarzour, Ha Won Kim, N. Weintraub   +2 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Jefferson Vascular Center Among the First to Implant Fenestrated Aortic Grafts [PDF]

, 2013
The Jefferson Vascular Center brings together surgical and medical specialties to provide comprehensive care to patients with vascular diseases (diseases of blood vessels) and thrombotic (blood-clotting) disorders, as well as care of complex vascular ...

core   +1 more source

Outpatient Treatment in Low-Risk Pulmonary Embolism Patients Receiving Direct Acting Oral Anticoagulants Is Associated With Cost Savings

Clinical and Applied Thrombosis/Hemostasis, 2020
Direct oral anticoagulants (DOAC) are first line treatment for pulmonary embolism (PE). Treatment of acute PE is traditionally hospital based and associated with high costs.
Raein Ghazvinian MD, Johan Elf MD, Sofia Löfvendahl Economist, Jan Holst MD, Anders Gottsäter MD   +4 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source