Results 71 to 80 of about 950,338 (392)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Suppression of vascular endothelial growth factor expression by cannabinoids in a canine osteosarcoma cell line

Veterinary Medicine: Research and Reports, 2013
Andreza S Figueiredo,1 Hiram J García-Crescioni,1 Sandra C Bulla,1 Matthew K Ross,2 Chelsea McIntosh,1 Kari Lunsford,3 Camilo Bulla11Department of Pathobiology and Population Medicine, 2Department of Basic Sciences, 3Department of Clinical ...
Figueiredo AS, García-Crescioni HJ, Bulla SC, Ross MK, McIntosh C, Lunsford K, Bulla C   +6 more
doaj  

Anti-inflammatory and immunomodulatory effects of rosuvastatin in patients with low-to-moderate cardiovascular risk

Acta Pharmaceutica, 2022
Statins have shown anti-inflammatory pleiotropic effects in subjects with/at risk of cardiovascular disease. The aim of this study was to evaluate the inflammatory/immunomodulatory properties of rosuvastatin in subjects at low-to-moderate cardiovascular ...
VAVLUKIS ANA, VAVLUKIS MARIJA, DIMOVSKI ALEKSANDAR, PETRUSHEVSKA GORDANA, EFTIMOV ALEKSANDAR, DOMAZETOVSKA SASHKA, MLADENOVSKA KRISTINA   +6 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Intraocular and systemic levels of vascular endothelial growth factor in advanced cases of retinopathy of prematurity

Clinical Ophthalmology, 2010
Raul Velez-Montoya1, Carmen Clapp2, Jose Carlos Rivera2, Gerardo Garcia-Aguirre1, Virgilio Morales-Cantón1, Jans Fromow-Guerra1, Jose Luis Guerrero-Naranjo1, Hugo Quiroz-Mercado31Retina Department Asociación para Evitar la Ceguera ...
Raul Velez-Montoya, Carmen Clapp, Jose Carlos Rivera, et al   +3 more
doaj  

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis

Health Technology Assessment
Background Diabetic retinopathy is a major cause of sight loss in people with diabetes. The most severe form, proliferative diabetic retinopathy, carries a high risk of vision loss, vitreous haemorrhage, macular oedema and other harms.
Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, John G Lawrenson, Tunde Peto, David Steel   +12 more
doaj   +1 more source

Up-regulation of endocrine gland-derived vascular endothelial growth factor but not vascular endothelial growth factor in human ectopic endometriotic tissue [PDF]

, 2010
Objective: To study the expression of vascular endothelial growth factor (VEGF), endocrine gland-derived VEGF (EG-VEGF/PK1), and its receptors (PKR1 and PKR2) in eutopic and ectopic endometrial tissues. Design: A case-control study.
Chan, RWS, Cheong, AWY, Ho, PC, Lee, KF, Lee, YL, Ng, EHY, Yeung, WSB   +6 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Angiogenesis in Ocular and Extraocular Sebaceous Carcinoma

Acta Dermato-Venereologica, 2019
To shed more light on the pathogenesis of sebaceous carcinoma, we analysed the expression of proteins related to angiogenesis in 18 ocular and 22 extraocular sebaceous carcinomas using a broad panel of immunohistochemical markers.
Ferdinand Toberer, Holger A. Haenssle, Arno Rütten, Dmitry Kazakov, Liubov Kastnerova, Alexander Enk, Wolfgang Hartschuh, Ines Bertlich, Julia Hartmann, Martin Laimer, Wolfgang Weyers, Peter Helmbold, Heinz Kutzner   +12 more
doaj   +1 more source

Vascular Endothelial Growth Factor (VEGF) and Platelet (PF-4) Factor 4 Inputs Modulate Human Microvascular Endothelial Signaling in a Three-Dimensional Matrix Migration Context [PDF]

, 2013
The process of angiogenesis is under complex regulation in adult organisms, particularly as it often occurs in an inflammatory post-wound environment. As such, there are many impacting factors that will regulate the generation of new blood vessels which ...
Adair, Aidoudi, Anastasiadis, Balasubramaniam, Ban, Barrientos, Beauchamp, Bernardini, Bodnar, Bodnar, Brantley-Sieders, Calalb, Campbell, Carmeliet, Carmeliet, Cheng, Chiu, Chung, Dephoure, Eminaga, Fang, Feil, Frey, Fujiwara, George, Gillitzer, Gupta, Hendrix, Hess, Hu, Hu, Huang, Jackson, Kanaji, Kasper, Kaully, Kawauchi, Keeley, Kikawa, Kim, Kirkpatrick, Kobayashi, Kundu, Larsen, Lee, Lim, Liu, Matozaki, Matsui, Mayya, Mehrad, Mendes, Miao, Miao, Miao, Mortensen, Naegle, Newman, Nichols, Noberini, Noberini, Norbury, O'Meara, Pasquale, Patrussi, Perkins, Perretti, Petrai, Platt, Poliakov, Potapova, Radke, Raingeaud, Ravichandran, Ren, Rimchala, Romanova, Rosenkilde, Roux, Saharinen, Sahota, Salcedo, Shao, Sherwood, Shikata, Shults, Singh, Slungaard, Soker, Sotirellis, Spangler, Squire, Su, Sulpice, Szekanecz, Tabruyn, Tcatchoff, Thalhammer, Tremper-Wells, Tsubouchi, Vandercappellen, Vandercappellen, Vindis, Vizcaíno, Walker-Daniels, Welburn, Werdich, Werner, Wykosky, Yancopoulos, Yi, Zhang, Zhang, Zhao   +113 more
core   +1 more source