Vascular Endothelial Growth Factor Receptor-1 Expression in Breast Cancer and Its Correlation to Vascular Endothelial Growth Factor A [PDF]
International Journal of Breast Cancer, 2013 VEGF-A is the most potent angiogenic factor in tumour angiogenesis. Its effects are mediated via two receptors VEGFR-1 and VEGFR-2. Primary aim of our study was to examine the expression of VEGFR-1 in breast cancer and its correlation to VEGF expression,
Nahida Srabovic +6 more
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Cheiradone: a vascular endothelial cell growth factor receptor antagonist [PDF]
BMC Cell Biology, 2008 Background Angiogenesis, the growth of new blood vessels from the pre-existing vasculature is associated with physiological (for example wound healing) and pathological conditions (tumour development).
Ahmed Nessar +8 more
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Vascular endothelial growth factor B, a novel growth factor for endothelial cells. [PDF]
Proceedings of the National Academy of Sciences, 1996 We have isolated and characterized a novel growth factor for endothelial cells, vascular endothelial growth factor B (VEGF-B), with structural similarities to vascular endothelial growth factor (VEGF) and placenta growth factor. VEGF-B was particularly abundant in heart and skeletal muscle and was coexpressed with VEGF in these and other tissues.
B, Olofsson +9 more
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Aldosterone, Vascular Endothelial Growth Factor, and Preeclampsia [PDF]
Hypertension, 2013 See related article, pp 1111–1117 The renin–angiotensin system (RAS) is one of the key players in volume and sodium homeostasis. Activation of the RAS leads to vasoconstriction, sodium retention, and volume expansion via the action of angiotensin II and the effector hormone of the RAS, aldosterone. The RAS can also respond to changes in plasma volume;
C. Delles, E. M. Freel
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Vascular Endothelial Growth Factor Induces Shc Association With Vascular Endothelial Cadherin [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002 Vascular endothelial (VE)-cadherin is endothelium specific, mediates homophilic adhesion, and is clustered at intercellular junctions. VE-cadherin is required for normal development of the vasculature in the embryo and for angiogenesis in the adult.
Adriana, Zanetti +6 more
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Intravitreal Injections with Vascular Endothelial Growth Factor Inhibitors: A Practical Approach [PDF]
Ophthalmology and Therapy, 2020 Intravitreal injections with vascular endothelial growth factor inhibitors constitute the most prevalent ophthalmic procedure in developed countries. Historically, there has been steady growth in the number of treatments performed of this kind, and projection studies estimate further growth in such treatments in the future.
Petri, Anne-Sofie +7 more
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Vascular Endothelial Growth Factor A Inhibition in Gastric Cancer [PDF]
Gastric Cancer, 2014 Angiogenesis is a vital process in the progression and metastasis of solids tumors including gastric adenocarcinoma. Tumors induce angiogenesis by secreting proangiogenic molecules such as vascular endothelial growth factor A (VEGF-A), and VEGF-A inhibition has become a common therapeutic strategy for many cancers.
Do Joong, Park +3 more
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Journal of Tissue Engineering, 2016 Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts +4 more
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Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment. [PDF]
PLoS ONE, 2013 There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability ...
Miyako Kondoh +8 more
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Gene Transfers of Vascular Endothelial Growth Factor-A, Vascular Endothelial Growth Factor-B, Vascular Endothelial Growth Factor-C, and Vascular Endothelial Growth Factor-D Have No Effects on Atherosclerosis in Hypercholesterolemic Low-Density Lipoprotein-Receptor/Apolipoprotein B48-Deficient Mice [PDF]
Circulation, 2005 Background— The role of vascular endothelial growth factors (VEGFs) in large arteries has been proposed to be either vasculoprotective or proatherogenic. Because VEGF family members are used for human therapy, it is important to know whether they could enhance atherogenesis.
Pia, Leppänen +7 more
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