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Biology of vascular endothelial growth factors [PDF]

FEBS Letters, 2006
Angiogenesis is the process by which new blood vessels are formed from existing vessels. The vascular endothelial growth factors (VEGFs) are considered as key molecules in the process of angiogenesis. The VEGF family currently includes VEGF‐A, ‐B, ‐C, ‐D, ‐E, ‐F and placenta growth factor (PlGF), that bind in a distinct pattern to three structurally ...
Seppo Ylä-Herttuala, Shalini Bhardwaj, Himadri Roy   +2 more
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Vascular Endothelial Growth Factor [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 1993
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration.
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The biology of vascular endothelial growth factors [PDF]

Cardiovascular Research, 2005
The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has provided tools for studying the vascular system in development as well as in diseases ranging from ischemic heart disease to cancer.
Tuomas Tammela, Karri Paavonen, Kari Alitalo, Berndt Enholm   +3 more
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The Biology of Vascular Endothelial Growth Factor [PDF]

Endocrine Reviews, 1997
The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1. Neovascularization (angiogenesis) is also implicated in the pathogenesis of a number of disorders.
Napoleone Ferrara, Terri Lynn Davis-Smyth   +1 more
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Vascular endothelial growth factors and vascular permeability [PDF]

Cardiovascular Research, 2010
Vascular endothelial growth factors (VEGFs) are key regulators of permeability. The principal evidence behind how they increase vascular permeability in vivo and in vitro and the consequences of that increase are addressed here. Detailed analysis of the published literature has shown that in vivo and in vitro VEGF-mediated permeability differs in its ...
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Vascular endothelial growth factor pathway

Pharmacogenetics and Genomics, 2010
Michael L. Maitlanda, Xing Jian Louc, Jacqueline Ramireza, Apurva A. Desaia, Dorit S. Berlinc, Howard L. McLeodb, Ralph R. Weichselbauma, Mark J. Rataina, Russ B. Altmanc, and Teri E. Kleinc aDepartment of Medicine, Section of Hematology/Oncology, University of Chicago, Maryland Avenue, Chicago, Illinois bUNC Institute for Pharmacogenomics and ...
Xing Jian Lou, Russ B. Altman, Jacqueline Ramírez, Howard L. McLeod, Teri E. Klein, Ralph R. Weichselbaum, Mark J. Ratain, Dorit S. Berlin, Apurva A. Desai, Michael L. Maitland   +9 more
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In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

Journal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts, Brooke L Farrugia, Rylie A Green, Jelena Rnjak-Kovacina, Penny J Martens   +4 more
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Development and Validation of a Vascular Endothelial Growth Factor A-associated Prognostic Model for Unresectable Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2023
Kun He,* Xinyu Liu,* Zelong Yang Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zelong Yang, Department
He K, Liu X, Yang Z
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Immunohistochemical study of VEGF-A, VEGFR-1, VEGFR-2 and CD34 expression in сolorectal adenocarcinoma progression

Patologìâ, 2019
Aim – to study VEGF-A, VEGFR-1, VEGFR-2 and CD34 immunohistochemical expression on the I, II, III, IV stages (pTNM) of colorectal adenocarcinoma development. Materials and methods.
M. A. Shyshkin
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Vascular Endothelial Growth Factor Receptor-1 Expression in Breast Cancer and Its Correlation to Vascular Endothelial Growth Factor A

International Journal of Breast Cancer, 2013
VEGF-A is the most potent angiogenic factor in tumour angiogenesis. Its effects are mediated via two receptors VEGFR-1 and VEGFR-2. Primary aim of our study was to examine the expression of VEGFR-1 in breast cancer and its correlation to VEGF expression,
Nahida Srabovic, Zlata Mujagic, Jasminka Mujanovic-Mustedanagic, Adaleta Softic, Zdeno Muminovic, Adi Rifatbegovic, Lejla Begic   +6 more
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