Results 11 to 20 of about 2,594,698 (191)
The biology of vascular endothelial growth factors [PDF]
Cardiovascular Research, 2005 The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has provided tools for studying the vascular system in development as well as in diseases ranging from ischemic heart disease to cancer.
Tuomas Tammela +3 more
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Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats
Clinics, 2011 INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei +5 more
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Induction of VEGF secretion from bone marrow stromal cell line (ST-2) by the dissolution products of mesoporous silica glass particles containing CuO and SrO [PDF]
J. Non-cryst. Solids. 500, 217-224 (2018), 2021 Certain biomaterials are capable of inducing the secretion of Vascular Endothelial Growth Factor (VEGF) from cells exposed to their biochemical influence, which plays a vital role in stimulating angiogenesis. Looking for this capacity, in this study three porous glasses were synthesized and characterized.
arxiv +1 more source
BMC Ophthalmology, 2017 Background To evaluate changes in central macular thickness (CMT) and visual outcome in patients with neovascular age-related macular degeneration (AMD) treated initially with bevacizumab and subsequently switched to either aflibercept or ranibizumab ...
Maria Waizel +7 more
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Archives of Medical Science, 2019 Introduction The aim of the study was to investigate the effects of vascular endothelial growth factor (VEGF) concentration in vitreous on postoperative complications after pars plana vitrectomy (PPV).
Faruk Nisic +6 more
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The Biology of Vascular Endothelial Growth Factor [PDF]
Endocrine Reviews, 1997 The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1. Neovascularization (angiogenesis) is also implicated in the pathogenesis of a number of disorders.
Napoleone Ferrara +1 more
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Tumor Biology, 2017 Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda +19 more
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Mechanical cell-matrix feedback explains pairwise and collective endothelial cell behavior in vitro [PDF]
PLoS Comput Biol 10(8): e1003774, 2014, 2013 In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells during vasculogenesis and angiogenesis. When seeded in an extracellular matrix, endothelial cells can form blood vessel-like structures, including vascular networks and sprouts.
arxiv +1 more source
Bridging Scales: a Hybrid Model to Simulate Vascular Tumor Growth and Treatment Response [PDF]
, 2023 Cancer is a disease driven by random DNA mutations and the interaction of many complex phenomena. To improve the understanding and ultimately find more effective treatments, researchers leverage computer simulations mimicking the tumor growth in silico.
arxiv +1 more source
Vascular endothelial growth factors and vascular permeability [PDF]
Cardiovascular Research, 2010 Vascular endothelial growth factors (VEGFs) are key regulators of permeability. The principal evidence behind how they increase vascular permeability in vivo and in vitro and the consequences of that increase are addressed here. Detailed analysis of the published literature has shown that in vivo and in vitro VEGF-mediated permeability differs in its ...
openaire +3 more sources