Results 11 to 20 of about 706,179 (309)

Vascular Endothelial Growth Factor Receptor-1 Expression in Breast Cancer and Its Correlation to Vascular Endothelial Growth Factor A [PDF]

International Journal of Breast Cancer, 2013
VEGF-A is the most potent angiogenic factor in tumour angiogenesis. Its effects are mediated via two receptors VEGFR-1 and VEGFR-2. Primary aim of our study was to examine the expression of VEGFR-1 in breast cancer and its correlation to VEGF expression,
Nahida Srabovic, Zlata Mujagic, Jasminka Mujanovic-Mustedanagic, Adaleta Softic, Zdeno Muminovic, Adi Rifatbegovic, Lejla Begic   +6 more
doaj   +3 more sources

Biology and therapeutic targeting of vascular endothelial growth factor A

Nature Reviews Molecular Cell Biology, 2023
The formation of new blood vessels, called angiogenesis, is an essential pathophysiological process in which several families of regulators have been implicated. Among these, vascular endothelial growth factor A (VEGFA; also known as VEGF) and its two tyrosine kinase receptors, VEGFR1 and VEGFR2, represent a key signalling pathway mediating ...
Lorena Pérez-Gutiérrez, Napoleone Ferrara   +1 more
openaire   +6 more sources

Cheiradone: a vascular endothelial cell growth factor receptor antagonist [PDF]

BMC Cell Biology, 2008
Background Angiogenesis, the growth of new blood vessels from the pre-existing vasculature is associated with physiological (for example wound healing) and pathological conditions (tumour development).
Ahmed Nessar, Matou Sabine, Elosta Abdul H, Choudhary Mohammad I, Mesaik Mohammad A, Slevin Mark, Hussain Sajjad, West David, Gaffney John   +8 more
doaj   +5 more sources

Vascular endothelial growth factor B, a novel growth factor for endothelial cells. [PDF]

Proceedings of the National Academy of Sciences, 1996
We have isolated and characterized a novel growth factor for endothelial cells, vascular endothelial growth factor B (VEGF-B), with structural similarities to vascular endothelial growth factor (VEGF) and placenta growth factor. VEGF-B was particularly abundant in heart and skeletal muscle and was coexpressed with VEGF in these and other tissues.
B, Olofsson, K, Pajusola, A, Kaipainen, G, von Euler, V, Joukov, O, Saksela, A, Orpana, R F, Pettersson, K, Alitalo, U, Eriksson   +9 more
openaire   +2 more sources

Aldosterone, Vascular Endothelial Growth Factor, and Preeclampsia [PDF]

Hypertension, 2013
See related article, pp 1111–1117 The renin–angiotensin system (RAS) is one of the key players in volume and sodium homeostasis. Activation of the RAS leads to vasoconstriction, sodium retention, and volume expansion via the action of angiotensin II and the effector hormone of the RAS, aldosterone. The RAS can also respond to changes in plasma volume;
C. Delles, E. M. Freel
openaire   +2 more sources

Vascular endothelial growth factor receptor-1 mRNA overexpression in peripheral blood as a useful prognostic marker in breast cancer [PDF]

, 2012
INTRODUCTION: Identification of useful markers associated with poor prognosis in breast cancer patients is critically needed. We previously showed that expression of vascular endothelial growth factor receptor-1 mRNA in peripheral blood may be useful to ...
Akemi Kataoka, Hiroaki Ueo, Hiroshi Yamaguchi, Koshi Mimori, Masahiko Watanabe, Masaki Mori, Masaru Kuranami, Norihiko Sengoku, Sayuri Akiyoshi, Shinji Ohno, Yoshimasa Kosaka   +10 more
core   +2 more sources

Switch to aflibercept or ranibizumab after initial treatment with bevacizumab in eyes with neovascular AMD

BMC Ophthalmology, 2017
Background To evaluate changes in central macular thickness (CMT) and visual outcome in patients with neovascular age-related macular degeneration (AMD) treated initially with bevacizumab and subsequently switched to either aflibercept or ranibizumab ...
Maria Waizel, Margarita G. Todorova, Michael Masyk, Katharina Wolf, Annekatrin Rickmann, Khaled Helaiwa, Björn R. Blanke, Peter Szurman   +7 more
doaj   +1 more source

Enhanced Vascularization of Cultured Skin Substitutes Genetically Modified to Overexpress Vascular Endothelial Growth Factor11The authors declared in writing to have no conflict of interest. [PDF]

, 2000
Cultured skin substitutes have been used as adjunctive therapies in the treatment of burns and chronic wounds, but they are limited by lack of a vascular plexus.
Supp, Dorothy M., Supp, Andrew P., Boyce, Steven T., Bell, Sheila M.   +3 more
core   +3 more sources

Vascular Endothelial Growth Factor Induces Shc Association With Vascular Endothelial Cadherin [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2002
Vascular endothelial (VE)-cadherin is endothelium specific, mediates homophilic adhesion, and is clustered at intercellular junctions. VE-cadherin is required for normal development of the vasculature in the embryo and for angiogenesis in the adult.
Adriana, Zanetti, Maria Grazia, Lampugnani, Giovanna, Balconi, Ferruccio, Breviario, Monica, Corada, Luisa, Lanfrancone, Elisabetta, Dejana   +6 more
openaire   +2 more sources

Clinical-functional and molecular characteristics of comorbid pathology (vibration disease combined with arterial hypertension)

Атеросклероз, 2022
Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko, Lyubov A. Shpagina, Alena M. Gorbunova, Ilya S. Shpagin, Yanina S. Sergeeva   +4 more
doaj   +1 more source