Results 21 to 30 of about 412,396 (315)

The role of vascular endothelial growth factor in ossification [PDF]

International Journal of Oral Science, 2012
Osteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair.Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF,
Ying-Ying Tan, A. Bakr M. Rabie, Ricky W. K. Wong, Yanqi Yang, Alex Wenden, Linkun Zhang, Linkun Zhang   +6 more
openaire   +5 more sources

Immunohistochemical Expression of Vascular Endothelial Growth Factor and Its Correlation With Tumor Grade in Breast Ductal Carcinoma [PDF]

Acta Medica Iranica, 2011
Breast cancer is the most common cause of cancer-related death in female, after lung cancer. Angiogenesis is essential for tumor growth and metastasis; therefore, antiangiogenesis strategies for treatment of cancer are currently an issue of interest. The
Laleh Vahedi Larijani, Roghaieh Moghimpour, Saeid Abediankenari, Ahmadreza Bekhradnia, Farshad Naghshvar, Omid Emadian, Maryam Ghasemi   +6 more
doaj   +2 more sources

Vascular endothelial growth factor in relation to the development of hepatocellular carcinoma in hepatitis C virus patients treated by direct-acting antivirals

Egyptian Liver Journal, 2021
Background Hepatocellular carcinoma (HCC) comprises 5.6% of all cancers worldwide representing the sixth most common cancer. It is also the fourth most common cause of cancer-related mortality.
Ahmed Mohamed ElGhandour, Essam Mohamed Bayoumy, Wesam Ahmed Ibrahim, Moataz Mohamed Sayed, Ashraf Bekheet Salama, Nahla Mohamed Teama, Mohamed Magdy Salama   +6 more
doaj   +1 more source

Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment. [PDF]

PLoS ONE, 2013
There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability ...
Miyako Kondoh, Noritaka Ohga, Kosuke Akiyama, Yasuhiro Hida, Nako Maishi, Alam Mohammad Towfik, Nobuo Inoue, Masanobu Shindoh, Kyoko Hida   +8 more
doaj   +1 more source

Newly Identified Peptide, Peptide Lv, Promotes Pathological Angiogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background We recently discovered a small endogenous peptide, peptide Lv, with the ability to activate vascular endothelial growth factor receptor 2 and its downstream signaling.
Liheng Shi, Min Zhao, Colette A. Abbey, Shu‐Huai Tsai, Wankun Xie, Dylan Pham, Samantha Chapman, Kayla J. Bayless, Travis W. Hein, Robert H. Rosa, Michael L. Ko, Lih Kuo, Gladys Y.‐P. Ko   +12 more
doaj   +1 more source

The function of vascular endothelial growth factor

BioFactors, 2009
AbstractVascular endothelial growth factor (VEGF) is considered the master regulator of angiogenesis during growth and development, as well as in disease states such as cancer, diabetes, and macular degeneration. This review details our current understanding of VEGF signaling and discusses the benefits and unexpected side effects of promising anti ...
Bonnie J. Nieves, Brad A. Bryan, Patricia A. D'Amore   +2 more
openaire   +4 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Vascular endothelial growth factor in degenerating intervertebral discs of rat caudal vertebrae

Spine Surgery and Related Research, 2018
Introduction: Discogenic back pain remains poorly understood with respect to etiopathogenesis, despite being a considerable burden. We sought to examine the expression of vascular endothelial growth factor in injured intervertebral discs in rat caudal ...
Jun Sato, Kazuhide Inage, Masayuki Miyagi, Yoshihiro Sakuma, Kazuyo Yamauchi, Masahiko Suzuki, Masao Koda, Takeo Furuya, Junichi Nakamura, Yawara Eguchi, Miyako Suzuki, Go Kubota, Yasuhiro Oikawa, Takeshi Sainoh, Kazuki Fujimoto, Yasuhiro Shiga, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Kazuhisa Takahashi, Seiji Ohtori, Sumihisa Orita   +24 more
doaj   +1 more source

TFEB‐translocated and ‐amplified renal cell carcinoma with VEGFA co‐amplification: A case of long‐term control by multimodal therapy including a vascular endothelial growth factor‐receptor inhibitor

IJU Case Reports, 2023
Introduction Renal cell carcinoma with TFEB amplification is rare and reportedly aggressive. We herein report a case of renal cell carcinoma with TFEB translocation and amplification in which long‐term control was achieved by multimodal therapy including
Hajime Takamori, Akiko Miyagi Maeshima, Ikuma Kato, Masaya Baba, Eijiro Nakamura, Yoshiyuki Matsui   +5 more
doaj   +1 more source