Results 11 to 20 of about 28,223,317 (305)

Co-regulatory potential of vascular endothelial growth factor–A and vascular endothelial growth factor–C in thyroid carcinoma [PDF]

Human Pathology, 2013
Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels. The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and their impact in angiogenesis and metastases in thyroid cancers. VEGF-A and VEGF-C mRNA and protein expression was investigated in 136 thyroid cancers (123 papillary thyroid ...
Salajegheh, Ali, Pakneshan, Sahar, Rahman, Atiqur, Dolan-Evans, Elliot, Zhang, Sheldon, Kwong, Esther, Gopalan, Vinod, Lo, Chung-Yau, Smith, Robert Anthony, Lam, Alfred King-Yin   +9 more
openaire   +6 more sources

Vascular endothelial growth factor-C in activating vascular endothelial growth factor receptor-3 and chemokine receptor-4 in melanoma adhesion. [PDF]

J Cell Mol Med, 2022
AbstractVascular endothelial growth factor‐C (VEGF‐C) binds to receptor vascular endothelial growth factor receptor‐3 (VEGFR‐3) expressed on lymphatic endothelial and melanoma cells. Binding of VEGF‐C to VEGFR‐3 enhances receptor phosphorylation that activates mitogen‐activated protein kinase (MAP‐K) and phosphatidylinositol‐3‐kinase (PI3K).
Hlophe YN, Joubert AM.
europepmc   +4 more sources

Vascular Targeted Agents for the Treatment of Angiosarcoma [PDF]

, 2013
Background: Angiogenesis is the process of new blood vessel formation, and is regulated by angiogenic growth factors including vascular endothelial growth factor (VEGF). Angiosarcomas are rare, aggressive vascular tumours.
P J Woll (16226153), R J Young (13425891), C A Staton (16226156), Malcolm Reed (4465876), Young, Robin, N J Brown (13424178)   +5 more
core   +5 more sources

Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases. [PDF]

J Am Soc Nephrol, 2016
Polycystic kidney diseases (PKD) are genetic disorders characterized by progressive epithelial cyst growth leading to destruction of normally functioning renal tissue. Current therapies have focused on the cyst epithelium, and little is known about how the blood and lymphatic microvasculature modulates cystogenesis.
Huang JL, Woolf AS, Kolatsi-Joannou M, Baluk P, Sandford RN, Peters DJ, McDonald DM, Price KL, Winyard PJ, Long DA.   +9 more
europepmc   +7 more sources

Vascular endothelial growth factor C promotes survival of retinal vascular endothelial cells via vascular endothelial growth factor receptor-2 [PDF]

British Journal of Ophthalmology, 2006
To determine vascular endothelial growth factor C (VEGF-C) expression in retinal endothelial cells, its antiapoptotic potential and its putative role in diabetic retinopathy.Cultured retinal endothelial cells and pericytes were exposed to tumour necrosis factor (TNF)alpha and VEGF-C expression determined by reverse transcriptase-polymerase chain ...
Bojun, Zhao, Gill, Smith, Jun, Cai, Aihua, Ma, Mike, Boulton   +4 more
openaire   +2 more sources

The vascular endothelial growth factor +405G>C polymorphism in endometriosis [PDF]

Human Reproduction, 2007
Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis potentially contributing to the pathogenesis of endometriosis. The aim of this study was to investigate the potential association between the single nucleotide polymorphism +405G>C of the VEGF gene with the risk of endometriosis, for the first time in the Caucasian ...
D. Gentilini, E. Somigliana, P. Viganò, M. Vignali, M. Busacca, A. M. Di Blasio   +5 more
openaire   +3 more sources

Expression of vascular endothelial growth factor C in human pterygium [PDF]

Histochemistry and Cell Biology, 2012
Vascular endothelial growth factor C (VEGF-C) and its receptor VEGFR-3 mediate lymphangiogenesis. In this study, we analyzed the expression of VEGF-C and VEGFR-3 as well as lymphatic vessels in the pterygium and normal conjunctiva of humans. Fifteen primary nasal pterygia and three normal bulbar conjunctivas, surgically removed, were examined in this ...
Fukuhara, Junichi, Kase, Satoru, Ohashi, Tsutomu, Ando, Ryo, Dong, Zhenyu, Noda, Kousuke, Ohguchi, Takeshi, Kanda, Atsuhiro, Ishida, Susumu   +8 more
openaire   +4 more sources

Intraluminal application of vascular endothelial growth factor enhances healing of microvascular anastomosis in a rat model [PDF]

, 2005
Background: Early reconstitution after injury to the endothelium is an important feature for reducing a number of vessel wall pathologies. We investigated the effect of vascular endothelial growth factor ( VEGF) and its impact on the vascular remodeling ...
Hollenberg, S. M., Shakibaei, M., Kossmehl, P., Faramarzi, S., Paul, M., Schulze-Tanzil, G., Infanger, M., Grosse, J., Grimm, D.   +8 more
core   +1 more source

Electroacupuncture ameliorates inflammatory response of mice with acute myocardial ischemia by regulating vascular endothelial growth factor C/vascular endothelial growth factor receptor 3 pathway

针刺研究, 2022
Objective To observe the effect of electroacupuncture(EA) on the cardiac function, lymphatic markers, macrophage and inflammatory cytokines in acute myocardial ischemia(AMI) mice, so as to explore its mechanism in improving AMI.
ZUO Hai-yan, WU Sheng-bing, WU Xin, CUI Shuai, WANG Kun, ZHU Chao, WANG Lei, ZHOU Mei-qi   +7 more
doaj   +2 more sources

Expression of Hypoxia-inducible factor 1-α and Vascular endothelial growth factor-C in locally advanced breast cancer patients

Clinics, 2011
BACKGROUND: Locally advanced breast cancers are more prevalent in underdeveloped countries. Targeted therapy has been improved to identify hallmarks that are specific to these subtypes of tumors.
Luiz Gustavo Oliveira Brito, Viviane Fernandes Schiavon, Jurandyr Moreira de Andrade, Daniel Guimarães Tiezzi, Fernanda Maris Peria, Heitor Ricardo Cosiski Marana   +5 more
doaj   +1 more source