Results 31 to 40 of about 28,223,317 (305)

Clinicopathological impact of VEGFR2 and VEGF‐C in patients with EGFR‐major mutant NSCLC receiving osimertinib

Thoracic Cancer, 2023
Background Vascular endothelial growth factor (VEGF) has been identified as one of the resistant mechanisms to epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐TKIs).
Kyoichi Kaira, Hisao Imai, Atsuto Mouri, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Kunihiko Kobayashi, Tomonori Kawasaki, Masanori Yasuda, Hiroshi Kagamu   +10 more
doaj   +1 more source

Effect of antihypertensive therapy with alpha methyldopa on levels of angiogenic factors in pregnancies with hypertensive disorders. [PDF]

, 2008
Antihypertensive drugs are believed to lower blood pressure in pre-eclampsia by direct or central vasodilatory mechanisms. However, they could also act by decreasing production of anti-angiogenic proteins involved in the pathophysiology of hypertension ...
Muttukrishna Shanthi, Muttukrishna, S, Khalil Asma, Khalil, A, Jauniaux, E, Harrington, K, Jauniaux Eric, Kevin Harrington, Harrington Kevin, Shanthi Muttukrishna, Asma Khalil, Eric Jauniaux   +11 more
core   +2 more sources

Proximal tubule dysfunction is associated with podocyte damage biomarkers nephrin and vascular endothelial growth factor in type 2 diabetes mellitus patients: a cross-sectional study. [PDF]

PLoS ONE, 2014
There is an ongoing debate as to whether early diabetic nephropathy in Type 2 diabetes mellitus may be attributed to the glomerulus or to the proximal tubule.
Ligia Petrica, Adrian Vlad, Gheorghe Gluhovschi, Florica Gadalean, Victor Dumitrascu, Cristina Gluhovschi, Silvia Velciov, Flaviu Bob, Daliborca Vlad, Roxana Popescu, Oana Milas, Sorin Ursoniu   +11 more
doaj   +1 more source

Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis. [PDF]

PLoS ONE, 2012
Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine ...
Frédéric Larrieu-Lahargue, Alana L Welm, Marion Bouchecareilh, Kari Alitalo, Dean Y Li, Andreas Bikfalvi, Patrick Auguste   +6 more
doaj   +1 more source

VEGF-C and podoplanin, as biomarkers of sepsis. An experimental study

Romanian Journal of Laboratory Medicine, 2021
Background: Sepsis is the leading cause of morbidity and mortality in intensive care units. This study explored the possible role of vascular endothelial growth factor-C (VEGF-C) and podoplanin (PDPN) in sepsis.
Almasy Emoke, Szederjesi Janos, Grigorescu Bianca-Liana, Gurzu Simona, Lazar Alexandra, Raduly Gergo, Man Adrian, Oprica Madalina, Saplacan Irina, Copotoiu Sanda-Maria   +9 more
doaj   +1 more source

Gene Transfers of Vascular Endothelial Growth Factor-A, Vascular Endothelial Growth Factor-B, Vascular Endothelial Growth Factor-C, and Vascular Endothelial Growth Factor-D Have No Effects on Atherosclerosis in Hypercholesterolemic Low-Density Lipoprotein-Receptor/Apolipoprotein B48-Deficient Mice [PDF]

Circulation, 2005
Background— The role of vascular endothelial growth factors (VEGFs) in large arteries has been proposed to be either vasculoprotective or proatherogenic. Because VEGF family members are used for human therapy, it is important to know whether they could enhance atherogenesis.
Pia, Leppänen, Suvi, Koota, Ivana, Kholová, Jonna, Koponen, Christina, Fieber, Ulf, Eriksson, Kari, Alitalo, Seppo, Ylä-Herttuala   +7 more
openaire   +2 more sources

Cerebral and systemic endothelial dysfunction in migraine: Current knowledge and perspective [PDF]

Romanian Journal of Neurology, 2021
Migraine still causes a high rate of disability and is reported to increase the risk of cardiovascular and cerebrovascular diseases. Endothelial dysfunction is considered to be one of the underlying mechanisms linking migraine and vascular disorders ...
I Made Oka Adnyana, Valentina Tjandra Dewi   +1 more
doaj   +1 more source

Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma [PDF]

Cancer, 2004
AbstractBACKGROUNDThe vascular endothelial growth factor (VEGF) family and VEGF receptors (VEGFR) play an essential role in the angiogenesis of both pathologic and nonpathologic conditions. However, the prognostic significance of VEGF and VEGFR expression in ovarian carcinoma is unclear.METHODSThe tissue expression levels of VEGF‐A, VEGF‐C, VEGFR‐2 ...
Naoyo, Nishida, Hirohisa, Yano, Kan, Komai, Takashi, Nishida, Toshiharu, Kamura, Masamichi, Kojiro   +5 more
openaire   +2 more sources

Vascular endothelial growth factor +405G/C polymorphism as a predictor of diabetic retinopathy

Bulletin of the National Research Centre, 2020
Background Diabetic retinopathy is a multistage event, and the most important of it is angiogenesis. The possible association between vascular endothelial growth factor (VEGF) +405G/C gene polymorphism and various diseases, in which angiogenesis might be
Azza K. Amer, Nervana A. Khalaf, Safia H. Aboelmakarem, Mehry S. Elsobky, Mona R. Abdelrasoul, Amira A. Abdelazeem, Shahira R. Noweir, Safa Refaat, Leqaa A. Moemen, Soheir A. Mohammed, Mona A. Abdelhameed, Mohmoud M. Kenawy, Manal H. Abuelela, Marwa A. Fouly, Olfat A. Hassanin, Sherif M. Saadeldin Karawya, Zeinab M. Osman   +16 more
doaj   +1 more source

Lymphangiogenic Markers and Their Impact on Nodal Metastasis and Survival in Non-Small Cell Lung Cancer--A Structured Review with Meta-Analysis. [PDF]

PLoS ONE, 2015
In non-small cell lung cancer (NSCLC), nodal metastasis is an adverse prognostic factor. Several mediating factors have been implied in the development of nodal metastases and investigated for predictive and prognostic properties in NSCLC. However, study
Thomas K Kilvaer, Erna-Elise Paulsen, Sigurd M Hald, Tom Wilsgaard, Roy M Bremnes, Lill-Tove Busund, Tom Donnem   +6 more
doaj   +1 more source