Results 51 to 60 of about 932,558 (375)

Effect and Mechanism of EGFL7 Downregulation in Human Osteosarcoma Cells on the Biological Function of Co-cultured HUVEC

Balkan Medical Journal, 2018
Background: Even though epidermal growth factor-like domain 7 is known to be overexpressed in osteosarcoma and is associated with poor clinical outcome, few reports are available regarding its mechanism.
Xia Li, Li-Feng Liu, Yang-Zhou Liu, Yu-Tao Pan, Guang Li, Qing-You Lu, Zeng-Chun Li   +6 more
doaj   +1 more source

Vascular endothelial growth factor polymorphisms (−460C/T, +405G/C, and 936C/T) and endometriosis: their influence on vascular endothelial growth factor expression

Fertility and Sterility, 2009
To analyze three functional vascular endothelial growth factor (VEGF) polymorphisms (-460C/T, +405G/C, and 936C/T) in women with and without endometriosis and their correlation with VEGF expression in endometrial tissue and peritoneal fluid (PF).Case-control study.University-based hospital.One hundred eighty-six women with endometriosis and 180 ...
Raul Cosin, Francisco España, Juan Gilabert-Estellés, Juan Gilabert, Luis A. Ramón, Amparo Estellés, Alberto Romeu   +6 more
openaire   +4 more sources

M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression

Clinics, 2012
OBJECTIVES: Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis.
Bicheng Zhang, Yafei Zhang, Guoqing Yao, Juan Gao, Bo Yang, Yong Zhao, Zhiguo Rao, Jianfei Gao   +7 more
doaj   +1 more source

Expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 in ovarian epithelial tumors

Chinese Journal of Cancer Research, 2007
Objective To explore the role of vascular endothelial growth factor-C (VEGF-C) in the process of angiogenesis, lymphangiogenesis and lymphatic metastasis in epithelial ovarian tumors.
Fu Xiao-yan (傅晓艳), Lin Xing-qiu (林兴秋), Zhang Ning (张宁), Li Ji-cheng (李继承), Ding Ming-xing (丁明星)   +4 more
openaire   +2 more sources

Biosynthesis of Vascular Endothelial Growth Factor-D Involves Proteolytic Processing Which Generates Non-covalent Homodimers*

Journal of Biological Chemistry, 1999
Vascular endothelial growth factor-D (VEGF-D) binds and activates the endothelial cell tyrosine kinase receptors VEGF receptor-2 (VEGFR-2) and VEGF receptor-3 (VEGFR-3), is mitogenic for endothelial cells, and shares structural homology and receptor ...
S. Stacker, K. Stenvers, C. Caesar, A. Vitali, T. Domagala, E. Nice, S. Roufail, R. Simpson, Robert J. Moritz, Terhi Karpanen, K. Alitalo, M. G. Achen   +11 more
semanticscholar   +1 more source

Interrelationship between circulating vascular еndothelial growth factor-1 and high-sensitive C-reactive protein in stage III arterial hypertension patients

Zaporožskij Medicinskij Žurnal, 2013
Introduction. Arterial hypertension is one of the most important causes of mortality in the world. Vascular endothelial growth factor-1 (VEGF-1) pathways are the most frequently involved in hypertension development, especially related cardiovascular ...
A. E. Berezin, O. A. Lisovaya
doaj   +1 more source

Hepatocyte growth factor increases vascular endothelial growth factor-A production in human synovial fibroblasts through c-Met receptor pathway. [PDF]

PLoS ONE, 2012
BACKGROUND: Angiogenesis is essential for the progression of osteoarthritis (OA). Hepatocyte growth factor (HGF) is an angiogenic mediator, and it shows elevated levels in regions of OA.
Yu-Min Lin, Yuan-Li Huang, Yi-Chin Fong, Chun-Hao Tsai, Ming-Chih Chou, Chih-Hsin Tang   +5 more
doaj   +1 more source

Expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 in esophageal squamous cell carcinoma

Oncology Letters, 2014
Lymph node metastasis is one of the most important prognostic factors in esophageal squamous cell carcinoma (ESCC). Vascular endothelial growth factor (VEGF)-C and its receptor, VEGF receptor-3 (VEGFR-3), are key in the process of lymphangiogenesis.
Itaru Omoto, Yasuto Uchikado, Yuko Kijima, Yoshiaki Kita, Masataka Matsumoto, Hiroyuki Shinchi, Tetsuhiro Owaki, Shinichi Ueno, Tetsuro Setoyama, Hiroshi Okumura, Shoji Natsugoe, Sumiya Ishigami   +11 more
openaire   +4 more sources

Vascular Endothelial Growth Factor-C Accelerates Diabetic Wound Healing [PDF]

The American Journal of Pathology, 2006
Diabetes impairs numerous aspects of tissue repair. Failure of wound angiogenesis is known to delay diabetic wound healing, whereas the importance of lymphangiogenesis for wound healing is unclear. We have examined whether overexpression of vascular endothelial growth factor (VEGF)-C via an adenoviral vector could improve the healing of full-thickness ...
Kari Alitalo, Tuomas Tammela, Anne Saaristo, Anniina Fārkkilā, Marika J. Karkkainen, Seppo Ylä-Herttuala, Erkki Suominen   +6 more
openaire   +3 more sources

Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis.

Genes & Development, 2011
Neural stem cells (NSCs) are slowly dividing astrocytes that are intimately associated with capillary endothelial cells in the subventricular zone (SVZ) of the brain.
C. Calvo, R. Fontaine, Jihane Soueid, T. Tammela, T. Makinen, C. Alfaro-Cervelló, F. Bonnaud, A. Miguez, Lucile Benhaim, Yunling Xu, M. Barallobre, Imane Moutkine, Johannes Lyytikkä, T. Tatlisumak, B. Pytowski, B. Zalc, W. Richardson, N. Kessaris, J. García-Verdugo, K. Alitalo, A. Eichmann, Jean-Léon Thomas   +21 more
semanticscholar   +1 more source