Results 51 to 60 of about 765,451 (393)

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

Arteriogenesis versus angiogenesis: similarities and differences [PDF]

, 2007
Cardiovascular diseases account for more than half of total mortality before the age of 75 in industrialized countries. To develop therapies promoting the compensatory growth of blood vessels could be superior to palliative surgical surgical ...
Eitenmüller, Inka, Heil, Matthias, Schaper, Wolfgang, Schmitz-Rixen, Thomas   +3 more
core   +1 more source

Effect and Mechanism of EGFL7 Downregulation in Human Osteosarcoma Cells on the Biological Function of Co-cultured HUVEC

Balkan Medical Journal, 2018
Background: Even though epidermal growth factor-like domain 7 is known to be overexpressed in osteosarcoma and is associated with poor clinical outcome, few reports are available regarding its mechanism.
Xia Li, Li-Feng Liu, Yang-Zhou Liu, Yu-Tao Pan, Guang Li, Qing-You Lu, Zeng-Chun Li   +6 more
doaj   +1 more source

VEGF is indirectly associated with NO production

, 2012
Background? Increased levels of vascular endothelial growth factor (VEGF) have been observed in patients with metabolic syndrome (MetS). Nitric oxide (NO) formation is reduced in MetS, but its relationship to VEGF production remains poorly defined.
Alberti, Barylski, Bergman, Birk, Blann, Cao, Conover, Doupis, Dullaart, Ersoy, Hagberg, Jackson, Jackson, Kakizawa, Kimura, Kimura, Loebig, Sandhofer, Siervo, Siervo, Siervo, Siervo, Siervo, Silha, Simera, Treins, Tsai, Valabhji, Vyzantiadis   +28 more
core   +1 more source

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]

, 2003
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A, Alitalo, K, Betsholtz, C, Fruttiger, M, Gerhardt, H, Golding, M, Jeltsch, M, Lundkvist, A, Mitchell, C, Ruhrberg, C, Shima, D   +10 more
core   +2 more sources

Expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 in esophageal squamous cell carcinoma

Oncology Letters, 2014
Lymph node metastasis is one of the most important prognostic factors in esophageal squamous cell carcinoma (ESCC). Vascular endothelial growth factor (VEGF)-C and its receptor, VEGF receptor-3 (VEGFR-3), are key in the process of lymphangiogenesis.
OMOTO, ITARU, MATSUMOTO, MASATAKA, OKUMURA, HIROSHI, UCHIKADO, YASUTO, SETOYAMA, TETSURO, KITA, YOSHIAKI, OWAKI, TETSUHIRO, KIJIMA, YUKO, SHINCHI, HIROYUKI, ISHIGAMI, SUMIYA, UENO, SHINICHI, NATSUGOE, SHOJI   +11 more
openaire   +3 more sources

M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression

Clinics, 2012
OBJECTIVES: Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis.
Bicheng Zhang, Yafei Zhang, Guoqing Yao, Juan Gao, Bo Yang, Yong Zhao, Zhiguo Rao, Jianfei Gao   +7 more
doaj   +1 more source

A Recombinant Mutant Vascular Endothelial Growth Factor-C that Has Lost Vascular Endothelial Growth Factor Receptor-2 Binding, Activation, and Vascular Permeability Activities [PDF]

Journal of Biological Chemistry, 1998
The vascular endothelial growth factor (VEGF) and the VEGF-C promote growth of blood vessels and lymphatic vessels, respectively. VEGF activates the endothelial VEGF receptors (VEGFR) 1 and 2, and VEGF-C activates VEGFR-3 and VEGFR-2. Both VEGF and VEGF-C are also potent vascular permeability factors.
V, Joukov, V, Kumar, T, Sorsa, E, Arighi, H, Weich, O, Saksela, K, Alitalo   +6 more
openaire   +2 more sources

The roles of endoglin gene in cerebrovascular diseases. [PDF]

, 2017
Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core   +2 more sources

Homologous Up-regulation of KDR/Flk-1 Receptor Expression by Vascular Endothelial Growth Factor in Vitro *

Journal of Biological Chemistry, 1998
We investigated the possibility that vascular endothelial growth factor (VEGF) treatment could regulate KDR/Flk-1 receptor expression in endothelial cells. Bovine adrenal cortex endothelial cells were incubated with 200 pmrhVEGF165 for 0–7 days.
Ben-Quan Shen, D. Y. Lee, H. Gerber, B. Keyt, N. Ferrara, T. F. Zioncheck   +5 more
semanticscholar   +1 more source