Results 241 to 250 of about 37,380,162 (289)

Cell-to-Cell Signaling Networks at the Blood-Brain Barrier in Health and Disease. [PDF]

Arterioscler Thromb Vasc Biol
McCarty JH.
europepmc   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Glycation at the Gate: A Brain Endothelial Glycocalyx Model and Therapeutic Roadmap for Alzheimer's Disease. [PDF]

Biomedicines
Tarawneh R.
europepmc   +1 more source

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Overview of Endomucin in Vascular Homeostasis and Disease. [PDF]

Microcirculation
Yang RF, Wang XR, Wang J, Du HB, Zhao ZA, Zhao ZG.   +5 more
europepmc   +1 more source

Hormonal metabolic burden in diabetic retinopathy: the diabetic retina as an endocrine-responsive target organ. [PDF]

Front Endocrinol (Lausanne)
Chen J, Zhang L.
europepmc   +1 more source

Endothelial proteomic response to Dirofilaria repens somatic antigens and the Dr20/22 protein reveals parasite-driven modulation of angiogenesis. [PDF]

Parasit Vectors
Collado-Cuadrado M, Montero-Calle A, Vázquez-Ávila S, Barderas R, Pękacz M, Zawistowska-Deniziak A, Sotillo J, Pericacho M, Morchón R.   +8 more
europepmc   +1 more source

Paracrine Signaling in Cell-Biomaterial Interactions in Scaffold Vascularization: A Mini Review. [PDF]

Biomimetics (Basel)
Cole A, Sultana N.
europepmc   +1 more source

Research Progress on Angiogenesis and Involution Mechanisms of Infantile Hemangioma and Its Regulation by Active Components of <i>Salvia miltiorrhiza</i>. [PDF]

Int J Mol Sci
Lu Y, Wu Y, Gu N, Wen K, Yang C, Huang X, Zeng D, Huang L, Wu S, Ma S, Liu Q.   +10 more
europepmc   +1 more source

The Role of Endothelial-Mesenchymal Transition (EndMT) in Aneurysm Formation. [PDF]

Biomedicines
Lange C, Kaschina E.
europepmc   +1 more source