Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF. [PDF]
Hemangiomas are tumors formed by hyper-proliferation of vascular endothelial cells. This is caused by elevated vascular endothelial growth factor (VEGF) signaling through VEGF receptor 2 (VEGFR2).
Damian Medici, Bjorn R Olsen
doaj +4 more sources
Association of vascular endothelial growth factor (VEGF) protein levels and gene polymorphism with the risk of chronic kidney disease [PDF]
Vascular endothelial growth factor (VEGF) is a heparin-specific growth factor specific for vascular endothelial cells and induces angiogenesis via binding to vascular endothelial growth factor receptor (VEGFR).
Yipin Liu +4 more
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VEGF-A, HGF and bFGF are involved in IL-17A-mediated migration and capillary-like vessel formation of vascular endothelial cells [PDF]
Background: Interleukin (IL)-17A possesses biological activities to promote vascular endothelial cell migration and microvessel development. Objective: To clarify which angiogenic factors are involved in IL-17A-modified angiogenesis-related functions of ...
Muneo Numasaki, Koyu Ito
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CIGB-247 is a vascular endothelial growth factor (VEGF)-based active immunotherapy and it is currently under investigation for cancer treatment. This specific active immunotherapy encompasses two vaccine candidates that use a human VEGF variant molecule ...
Javier Sánchez Ramírez +3 more
doaj +1 more source
Vascular endothelial growth factor (VEGF) is an angiogenic growth factor that acts primarily on endothelial cells, but numerous studies suggest that VEGF also acts on non-endothelial cells, including trophoblast cells.
Xiujun Fan +5 more
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Immunohistochemical Expression of Vascular Endothelial Growth Factor and Its Correlation With Tumor Grade in Breast Ductal Carcinoma [PDF]
Breast cancer is the most common cause of cancer-related death in female, after lung cancer. Angiogenesis is essential for tumor growth and metastasis; therefore, antiangiogenesis strategies for treatment of cancer are currently an issue of interest. The
Laleh Vahedi Larijani +6 more
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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A +10 more
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Comparing the Serum Level of Vascular Endothelial Growth Factor (VEGF) in Patients with Active Pulmonary Tuberculosis and the Control Group: A Case Control Study [PDF]
Background: Angiogenesis is seen in active pulmonary tuberculosis. One of the factors involved in angiogenesis is vascular endothelial growth factor (VEGF).
Abbas ali Niazi +5 more
doaj
Galectin-3 (Gal3) is a carbohydrate-binding protein reported to promote angiogenesis by influencing vascular endothelial growth factor-A receptor 2 (VEGFR2) signal transduction.
Issahy Cano +14 more
doaj +1 more source
VEGFR2 trafficking, signaling and proteolysis is regulated by the ubiquitin isopeptidase USP8 [PDF]
Vascular endothelial growth factor A (VEGF-A) regulates many aspects of vascular function. VEGF-A binding to vascular endothelial growth factor receptor 2 (VEGFR2) stimulates endothelial signal transduction and regulates multiple cellular responses ...
Adhikari +30 more
core +1 more source

