Results 231 to 240 of about 9,874,973 (297)

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

iNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li, Chaoyang Wang, Junci Chong, Zishu Liu, Boying Wang, Shiyu Liu, Xingcai Zhang, Hengrui Liu, Shuanglin Qin, ChuTse Wu, Beidong Chen, Zhigang Chang   +11 more
wiley   +1 more source

The Role of Serum Erythropoietin (EPO) and Vascular Endothelial Growth Factor (VEGF) in Pulse Wave Velocity (PWV) Among Hypertensive Patients: A Cross-Sectional Study. [PDF]

Cureus
Patil SM, Khodnapur JP, Das KK, Podder A.   +3 more
europepmc   +1 more source

Twenty‐four month clinical outcomes of modified coronally advanced tunnel technique with leukocyte‐ and platelet‐rich fibrin–functionalized porcine dermal matrix for single/multiple gingival recessions

Journal of Periodontology, EarlyView.
Abstract Background To report 24‐month clinical and 3D outcomes of single and multiple RT1 and RT2 gingival recessions treated with the modified coronally advanced tunnel (MCAT) technique and an L‐PRF‐functionalized porcine dermal matrix (PDM), as long‐term data on PDM in root coverage are scarce.
Erik Würflein, Katharina Herrmann, Anton Sculean, Kirstin Vach, Katja Nelson, Tobias Fretwurst, Gerhard Iglhaut, Florian Kernen   +7 more
wiley   +1 more source

Timing of Switching to Steroid Implants in Cases of Recalcitrant Diabetic Macular Edema Not Responding to Anti-vascular Endothelial Growth Factor (VEGF) Therapy: A Real-World Study. [PDF]

Cureus
Raizada S, Al Kandari J, Al Diab F, Al Sabah K, Kumar N, Mathew S, Al Dafiri Y, Abdul Jaleel T, Alrabiah M, Al Ajmi M.   +9 more
europepmc   +1 more source

An in vitro comparison of PDGF‐BB release from composite graft materials containing leukocyte‐rich platelet‐rich fibrin and platelet‐derived growth factor‐BB and β‐tricalcium phosphate

Journal of Periodontology, EarlyView.
Abstract Background The clinical efficacy of growth factors in regenerative procedures may depend on both dosage and sustained delivery during critical phases of healing. This study aimed to evaluate in vitro release kinetics of platelet‐derived growth factor‐BB (PDGF‐BB) from various graft materials, including recombinant human PDGF‐BB (rhPDGF‐BB ...
Farahnaz Fahimipour, Maggie A. Misch‐Haring, Ramzi V. Abou Arraj, Nicolaas C. Geurs, Maria L. Geisinger   +4 more
wiley   +1 more source

The effect of leukocyte–platelet‐rich fibrin in periodontal surgery on clinical parameters and patient‐related outcome measures: A randomized, controlled, clinical study

Journal of Periodontology, EarlyView.
Abstract Background This prospective study aimed to assess the clinical outcomes and patient‐related outcome measures (PROMs) of open flap debridement (OFD) alone versus open flap debridement with leukocyte–platelet‐rich fibrin (L‐PRF). Methods Twenty‐one patients were enrolled into a split‐mouth randomized clinical trial.
Jackson S. Sides, Archontia Palaiologou, Brian L. Mealey, Stephan J. Haney, Kerri Font, Charles A. Powell   +5 more
wiley   +1 more source

Association of Vascular Endothelial Growth Factor (VEGF) and Mouse Model Minute 2 (MDM2) Polymorphisms With Diabetic Retinopathy in a Northwest Indian Population: A Case-Control Study. [PDF]

Cureus
Buttar MS, Guleria K, Sharma S, Bhanwer A, Sambyal V.   +4 more
europepmc   +1 more source

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

Journal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu, Ming‐Ling Tsai, Tsu‐Hsuan Weng, Chi‐Hsiang Chung, Min‐Wen Fu, Wu‐Chien Chien   +5 more
wiley   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source