Results 61 to 70 of about 363,573 (256)

Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy

open access: yesCancer Treatment and Research Communications, 2022
Vascularization is fundamental to the growth and spread of tumor cells to distant sites. As a consequence, angiogenesis, the sprouting of new blood vessels from existing ones, is a characteristic trait of cancer.
Tobiloba C. Elebiyo   +7 more
doaj   +1 more source

Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus [PDF]

open access: yes, 2016
Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents.
Blazer-Yost, Bonnie L.   +6 more
core   +2 more sources

Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. [PDF]

open access: yes, 2018
The transmembrane protein neuropilin-1 (NRP1) promotes vascular endothelial growth factor (VEGF) and extracellular matrix signaling in endothelial cells (ECs).
Bosseboeuf, E   +8 more
core   +3 more sources

Vascular endothelium activation mechanisms study іn patients with psoriasis and essential hypertension

open access: yesZaporožskij Medicinskij Žurnal, 2016
The aim. To study Vascular Endothelial Growth Factor-A expression in patients with both psoriasis and hypertension. Methods and results. 102 patients were included. Vascular Endothelial Growth Factor-A level was detected with indirect ELISA method.
G. I. Makurina
doaj   +1 more source

Expressions of TGF-β1 and VEGF in patients with acute myeloid leukemia and associations with prognosis

open access: yesRomanian Journal of Laboratory Medicine, 2022
Background: To study the expressions of transforming growth factor-β1 (TGF-β1) and vascular endothelial growth factor (VEGF) in patients with acute myeloid leukemia (AML) and their values for prognosis.
Xu Yan, Yu Xianqiu, Zhang Xinlong
doaj   +1 more source

Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). [PDF]

open access: yes, 2005
Vascular endothelial growth factor (VEGF) was originally identified as an endothelial cell specific growth factor stimulating angiogenesis and vascular permeability. Some family members, VEGF C and D, are specifically involved in lymphangiogenesis.
Bouchier-Hayes, David J   +2 more
core   +2 more sources

Vascular Endothelial Growth Factor (VEGF) in Human Tooth Germ Center [PDF]

open access: yesInternational Journal of Immunopathology and Pharmacology, 2005
Many oncogenis and tumour suppressor genes found inside normal and pathological cells are fundamental for the processes of development, proliferation and tissue differentiation. The purpose of our study is to show the presence and a possible relationship of the VEGF protein during different phases of the development of human dental germ centers. After
MASTRANGELO, FILIBERTO   +9 more
openaire   +5 more sources

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function

open access: yesBiology Open, 2017
Cell surface receptors can undergo recycling or proteolysis but the cellular decision-making events that sort between these pathways remain poorly defined.
Gina A. Smith   +6 more
doaj   +1 more source

VEGF-C/VEGFR-3 and PDGF-B/PDGFR-b pathways in embryonic lymphangiogenesis [PDF]

open access: yes, 2008
The circulatory system comprises the blood vascular system and the lymphatic vascular system. These two systems function in parallel. Blood vessels form a closed system that delivers oxygen and nutrients to the tissues and removes waste products from the
Haiko, Paula
core  

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]

open access: yes, 2012
The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J.   +2 more
core   +1 more source

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