Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Di Qin (107446) +20 more
core +2 more sources
PRDM16 regulates arterial development and vascular integrity
Proper vascular formation is regulated by multiple signaling pathways. The vascular endothelial growth factor (VEGF) signaling promotes endothelial proliferation.
Michael Thompson +12 more
doaj +1 more source
Evaluation of different recruitment and randomisation methods in a trial of general practitioner-led interventions to increase physical activity : a randomised controlled feasibility study with factorial design [PDF]
Background: Interventions promoting physical activity by General Practitioners (GPs) lack a strong evidence base. Recruiting participants to trials in primary care is challenging.
Murphy, Marie +49 more
core +1 more source
BackgroundWith the move to virtual interviewing, residency websites are an important recruitment resource, introducing applicants to programs across the country and allowing for comparison. Recruitment is highly competitive from a
Katherine Jensen, Qi Yan, Mark G Davies
doaj +1 more source
Recruitment of the Vascular Endothelium into Neurovascular Coupling
In neurovascular coupling (NVC), neuronal activity in the brain leads to elevated local blood flow to satisfy the increased metabolic demands of the active tissue. The vascular endothelium has a major role in the modulation of blood flow, and here we explore the hypothesis that the endothelium has an important role in NVC.
Thomas Longden, Mark Nelson
openaire +1 more source
Vascular Mural Cells Promote Noradrenergic Differentiation of Embryonic Sympathetic Neurons
The sympathetic nervous system controls smooth muscle tone and heart rate in the cardiovascular system. Postganglionic sympathetic neurons (SNs) develop in close proximity to the dorsal aorta (DA) and innervate visceral smooth muscle targets.
Vitor Fortuna +7 more
doaj +1 more source
A molecular map of murine lymph node blood vascular endothelium at single cell resolution
The origin and diversity of blood vascular endothelial cells (BEC) in lymphoid tissues is unclear. Here, the authors profile murine BECs from peripheral lymph nodes by single cell analysis and identify subsets of cells specialised for immune cell ...
Kevin Brulois +18 more
doaj +1 more source
Progenitor/Stem Cells in Vascular Remodeling during Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is characterized by an important occlusive vascular remodeling with the production of new endothelial cells, smooth muscle cells, myofibroblasts, and fibroblasts.
France Dierick +4 more
doaj +1 more source
Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. [PDF]
Treatment of acute lung injury (ALI) remains an unsolved problem in intensive care medicine. As simvastatin exerts protective effects in inflammatory diseases we explored its effects on development of ALI and due to the importance of neutrophils in ALI ...
Vijayan, Santosh +49 more
core +2 more sources
The Collaborative Big Bang and Introduction to the European Vascular Research Collaborative.
2European Vascular Research Collaborative: Salome ...
European Vascular Research, Collaborative +1 more
core +1 more source

