Results 71 to 80 of about 419,114 (213)

Transplantation of Neural Crest-Like Cells Derived from Induced Pluripotent Stem Cells Improves Diabetic Polyneuropathy in Mice

open access: yesCell Transplantation, 2013
Impaired vascularity and nerve degeneration are the most important pathophysiological abnormalities of diabetic polyneuropathy (DPN). Therefore, regeneration of both the vascular and nervous systems is required for the treatment of DPN. The neural crest (
Tetsuji Okawa   +17 more
doaj   +1 more source

Mechanisms of Trained Innate Immunity in oxLDL Primed Human Coronary Smooth Muscle Cells

open access: yesFrontiers in Immunology, 2019
Objective: Damage and pathogen associated molecular patterns such as oxidized low-density lipoprotein (oxLDL) or bacillus Calmette-Guerin (BCG) vaccine can induce long term pro-inflammatory priming in monocytes and macrophages due to metabolic and ...
Lucia Schnack   +7 more
doaj   +1 more source

Dipeptidyl peptidase-4 inhibitor gemigliptin protects against vascular calcification in an experimental chronic kidney disease and vascular smooth muscle cells.

open access: yesPLoS ONE, 2017
Although dipeptidyl peptidase-4 inhibitors, a class of antidiabetic drugs, have various pleiotropic effects, it remains undetermined whether gemigliptin has a beneficial effect on vascular calcification.
Soon-Youn Choi   +7 more
doaj   +1 more source

Extract of Aquilaria crassna leaves and mangiferin are vasodilators while showing no cytotoxicity

open access: yesJournal of Traditional and Complementary Medicine, 2019
The leaves of Aquilaria spp. promote “physiological balance”, and are “cardiotonic and provide blood nourishment”. In Asia, these leaves are increasingly consumed as tea and claimed to provide benefits to cardiovascular function, albeit without any ...
Sutthinee Wisutthathum   +7 more
doaj   +1 more source

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

open access: yes, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

Endothelial dysfunction and vascular disease [PDF]

open access: yes, 2009
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth muscle, by releasing vasodilator substances. The best characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO).
Abeywardena   +460 more
core   +1 more source

An α-smooth muscle actin (acta2/αsma) zebrafish transgenic line marking vascular mural cells and visceral smooth muscle cells.

open access: yesPLoS ONE, 2014
Mural cells of the vascular system include vascular smooth muscle cells (SMCs) and pericytes whose role is to stabilize and/or provide contractility to blood vessels. One of the earliest markers of mural cell development in vertebrates is α smooth muscle
Thomas R Whitesell   +6 more
doaj   +1 more source

The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]

open access: yes, 2008
The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek   +5 more
core   +1 more source

Proliferative role of Kv11 channels in murine arteries [PDF]

open access: yes, 2017
K+ channels encoded by the ether-a-go-go related gene (ERG1 or KCNH2) are important determinants of the cardiac action potential. Expression of both cardiac isoforms (ERG1 and ERG1b) were identified in murine portal vein and distinctive voltage-gated K ...
Abbott   +35 more
core   +3 more sources

Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]

open access: yes, 2012
Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Greenwood, IA   +10 more
core   +1 more source

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