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Vascular Stiffness in Insulin Resistance and Obesity [PDF]
Obesity, insulin resistance, and type 2 diabetes are associated with a substantially increased prevalence of vascular fibrosis and stiffness, with attendant increased risk of cardiovascular and chronic kidney disease.
Guanghong eJia +5 more
doaj +3 more sources
Vascular Aging and Arterial Stiffness
Cardiovascular diseases (CVD) account annually for almost one third of all deaths worldwide. Among the CVD, systemic arterial hypertension (SAH) is related to more than half of those outcomes.
Luana de Rezende Mikael +8 more
doaj +5 more sources
Arterial stiffness and vascular aging: mechanisms, prevention, and therapy
Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. The central underlying mechanisms of cardiovascular diseases are vascular aging and associated arterial stiffness. Arterial stiffness is characterized by structural (e.g.,
Maximilian Jonathan Herzog +9 more
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Vascular stiffness and diastolic heart failure
Vascular stiffness is regarded as a result of degenerative processes potentiated by aging, hypertension, and other risk factors. Central hemodynamic changes are one of the serious sequels of high arterial stiffness, which gives rise to a chain of events ...
O M Drapkina, A N Kaburova
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Targeting Vascular Stiffness. [PDF]
Artery stiffening, a biomechanical vascular property closely related to but separate from hypertension, is a strong and independent cardiovascular disease risk factor that also predicts end-organ failure. Decreased aortic compliance elevates the mechanical load on the myocardium, increases peripheral pulse pressure which damages high-flow organs ...
Mack CP.
europepmc +3 more sources
Association of the human gut microbiota with vascular stiffness. [PDF]
AbstractGut microbiota metabolites have been mechanistically linked to inflammatory pathway activation and atherosclerosis, which are major causes of vascular stiffness (VS). Aiming to investigate if the gut microbiome might be involved in VS development, we performed a cross-sectional study (n = 3,087), nested within the population-based European ...
Cuadrat RRC +8 more
europepmc +8 more sources
Substrate stiffness directs diverging vascular fates [PDF]
Embryonic stem cells (ESC) are excellent cell culture systems for elucidating developmental signals that may be part of the stem cell niche. Although stem cells are traditionally induced using predominately soluble signals, the mechanical environment of the niche can also play a role in directing cells towards differential cell lineages.
Lian Wong +8 more
openaire +3 more sources
Association of vascular stiffness and geriatric syndromes in hypertensive elderly patients
Aim. To study the relationship of vascular stiffness (cardio-ankle vascular index (CAVI)) with frailty and other geriatric syndromes in hypertensive elderly patients.Material and methods. The study included 160 patients aged 60 to 101 years with verified
A. V. Luzina +3 more
doaj +1 more source
Arterial Stiffness and Vascular Aging: Effects of Hypertension
This review highlights the relationship of age and arterial hypertension observed in the aging process. The main structural and functional changes underlying the increase in vascular stiffness are analyzed. The similarity of vascular changes in aging and
E. S. Fomina, V. S. Nikiforov
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Exercise, Vascular Stiffness, and Tissue Transglutaminase [PDF]
Background Vascular aging is closely associated with increased vascular stiffness. It has recently been demonstrated that decreased nitric oxide ( NO )‐induced S‐nitrosylation of tissue transglutaminase ( TG 2) contributes to age‐related vascular stiffness ...
Steppan, Jochen +11 more
openaire +2 more sources

