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Targeting Vascular Stiffness. [PDF]
Arterioscler Thromb Vasc BiolArtery stiffening, a biomechanical vascular property closely related to but separate from hypertension, is a strong and independent cardiovascular disease risk factor that also predicts end-organ failure. Decreased aortic compliance elevates the mechanical load on the myocardium, increases peripheral pulse pressure which damages high-flow organs ...
Mack CP.
europepmc +4 more sources
Vascular aging, the vascular cytoskeleton and aortic stiffness [PDF]
Exploration of Medicine, 2021 Vascular aging, aortic stiffness and hypertension are mechanistically interrelated. The perspective presented here will focus mainly on the molecular mechanisms of age-associated increases in the stiffness of the vascular smooth muscle cell (VSMC).
Lova Prasadareddy Kajuluri +2 more
doaj +4 more sources
Vascular Stiffness in Insulin Resistance and Obesity [PDF]
Frontiers in Physiology, 2015 Obesity, insulin resistance, and type 2 diabetes are associated with a substantially increased prevalence of vascular fibrosis and stiffness, with attendant increased risk of cardiovascular and chronic kidney disease.
Guanghong eJia +5 more
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Vascular Aging and Arterial Stiffness
Arquivos Brasileiros de Cardiologia, 2017 Cardiovascular diseases (CVD) account annually for almost one third of all deaths worldwide. Among the CVD, systemic arterial hypertension (SAH) is related to more than half of those outcomes.
Luana de Rezende Mikael +8 more
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Frontiers in Vascular Stiffness
, 2023 The evaluation of vascular stiffness is becoming increasingly important in cardiovascular research to determine the properties of the arterial tree and clinically assesspatients. Current research addresses and debates some unresolved technical and methodological issues with measuring arterial stiffness, with the purpose of making it more reliable and ...
Paolo Salvi, Andrea Grillo
semanticscholar +3 more sources
Abdominal Aortic Endograft Implantation Immediately Induces Vascular Stiffness Gradients That May Promote Adverse Aortic Neck Dilatation: Results of A Porcine Ex Vivo Study. [PDF]
J Endovasc Ther, 2023 Schellinger IN +10 more
europepmc +3 more sources
The Clinical Significance and Application of Vascular Stiffness Measurements [PDF]
American Journal of Hypertension, 2018 Increasing evidence points out at vascular stiffness (and in particular aortic stiffness measured by pulse wave velocity) as a reliable biomarker of vascular aging, able to integrate in a single measure the overall burden of cardiovascular (CV) risk ...
P. Boutouyrie, R. Bruno
semanticscholar +5 more sources
Effects of Exercise on Arterial Stiffness: Mechanistic Insights into Peripheral, Central, and Systemic Vascular Health in Young Men [PDF]
MetabolitesBackground/Objectives: Arterial stiffness, a critical predictor of cardiovascular events, varies regionally across peripheral, central, and systemic arteries, necessitating targeted exercise interventions for young men.
Yongsheng Lan +6 more
doaj +2 more sources
Vascular stiffness and diastolic heart failure
Терапевтический архив, 2013 Vascular stiffness is regarded as a result of degenerative processes potentiated by aging, hypertension, and other risk factors. Central hemodynamic changes are one of the serious sequels of high arterial stiffness, which gives rise to a chain of events ...
O M Drapkina, A N Kaburova
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Frontiers in Cardiovascular Medicine, 2023 BackgroundArterial stiffness and medial vascular calcification, leading to isolated systolic blood pressure (BP), are major cardiovascular risk factors in patients with chronic kidney disease (CKD) and mineral bone disorders (MBD).
Richard Larivière +9 more
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