Life, 2022 Vascular aging, early vascular aging or supernormal vascular aging are concepts used for estimating the cardiovascular risk at a certain age. From the famous line of Thomas Sydenham that “a man is as old as his arteries” to the present day, clinical ...
C. Adam +5 more
semanticscholar +1 more source
Drug treatment of hypertension: focus on vascular health [PDF]
, 2016 Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C. +2 more
core +1 more source
Journal of applied physiology, 2020 Women are at higher risk for developing heart failure with preserved ejection fraction (HFpEF). We examined the utility of peak exercise blood pressure (BP) in identifying pre-clinical features of HFpEF, namely vascular and cardiac stiffness in middle ...
S. Sarma +10 more
semanticscholar +1 more source
Microvascular alterations in hypertension and vascular aging [PDF]
, 2017 Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra +5 more
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Smooth Muscle Cell Stiffness Syndrome – Revisiting the Structural Basis of Arterial Stiffness
Frontiers in Physiology, 2015 In recent decades, the pervasiveness of increased arterial stiffness in patients with cardiovascular disease has become increasingly apparent. Though this phenomenon has been well documented in humans and animal models of disease for well over a century,
Nancy L. Sehgel +3 more
doaj +1 more source
Effects of exercise training with blood flow restriction on vascular function in adults: a systematic review and meta-analysis [PDF]
PeerJ, 2021 Background Blood flow restricted exercise (BFRE) improves physical fitness, with theorized positive effects on vascular function. This systematic review and meta-analysis aimed to report (1) the effects of BFRE on vascular function in adults with or ...
Elisio A. Pereira-Neto +5 more
doaj +2 more sources
Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]
, 2017 The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C +3 more
core +1 more source
Vascular biology of ageing—implications in hypertension [PDF]
, 2015 Ageing is associated with functional, structural and mechanical changes in arteries that closely resemble the vascular alterations in hypertension. Characteristic features of large and small arteries that occur with ageing and during the development of ...
Harvey, Adam +2 more
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Progression of endothelial dysfunction, atherosclerosis, and arterial stiffness in stable kidney transplant patients: a pilot study. [PDF]
, 2020 BACKGROUND: Kidney transplant patients suffer from vascular abnormalities and high cardiovascular event rates, despite initial improvements post-transplantation. The nature of the progression of vascular abnormalities in the longer term is unknown.
Banerjee, D +5 more
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Alterations in vascular function in primary aldosteronism - a cardiovascular magnetic resonance imaging study [PDF]
, 2014 Introduction: Excess aldosterone is associated with increased cardiovascular risk. Aldosterone has a permissive effect on vascular fibrosis. Cardiovascular magnetic resonance imaging (CMR) allows study of vascular function by measuring aortic ...
A McCurley +40 more
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