Results 91 to 100 of about 127,835 (299)

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Integrating endothelium-derived hyperpolarization, nitric oxide, and prostacyclin pathways: the multimodal potential of human tissue kallikrein-1

Vascular Biology
Endothelial cells regulate vascular tone by releasing nitric oxide (NO) and prostacyclin (PGI2), as well as by initiating hyperpolarization of vascular smooth muscle cells through K+ channels and myoendothelial coupling.
Paolo Madeddu, Styliani Goulopoulou, David Wambeke   +2 more
doaj   +1 more source

Mechanisms of hypoxic vasodilation in ferret pulmonary arteries

, 1995
To investigate the mechanism of hypoxic pulmonary vasodilation we measured isometric tension in rings from ferret third- to fifth-generation intrapulmonary arteries mounted in organ baths (37 degrees C, 28% O2-5% CO2).
J. T. Sylvester, M. S. Dowless, M. R. Banta, C. M. Wiener, N. A. Flavahan   +4 more
core   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Vasomotor responses are similar between outbred UM-HET3 and inbred C57BL/6J male and female mouse mesenteric resistance arteries

Frontiers in Physiology
ObjectiveGenetically diverse UM-HET3 (HET3) mice have emerged as a more robust model of human large artery dysfunction than the commonly used inbred C57BL/6J (C57) mice. However, HET3 resistance artery function has not been examined.
Robin C. Looft-Wilson, Surya Naraynan, Kathleen Salmon, Ethan Wunibald, Brian Simmons, Connor Haitz, Vishakha Shah, Margaret Xu   +7 more
doaj   +1 more source

Role of adenosine in exercise vasodilation in dog gracilis muscle

, 1980
Theophylline, quinidine, and dipyridamole were used to evaluate the role of adenosine in exercise vasodilation in dog gracilis muscles perfused at low, constant flow.
J. L. Frierson, C. R. Honig
core   +1 more source

Dilatory effects and safety of a polyphenol-rich extract of Steganotaenia araliacea Hochst (Apiaceae) on rat aortic rings

Frontiers in Pharmacology
BackgroundHypertension is a major global public health concern. Many communities in developing countries still rely on medicinal plants as a source of primary healthcare for treatment of hypertension instead of conventional antihypertensive drugs ...
Newton Simfukwe, Lavina Prashar, James Nyirenda, Fastone Mathew Goma, Christian Chinyere Ezeala   +4 more
doaj   +1 more source

EDRF and norepinephrine-induced vasodilation in the canine coronary circulation

, 1995
Experiments were performed to characterize the role of endothelium-derived relaxing factor (EDRF) in coronary vasodilation caused by norepinephrine.
E. O. Feigl, K. Kroll, O. Traub, R. Van Bibber   +3 more
core   +1 more source

Revisiting the concept that interictal implies asymptomatic: Pulse wave amplitude drops uncover autonomic responses during generalized paroxysmal fast activities

Epilepsia, EarlyView.
Abstract Objective Interictal electroencephalographic (EEG) activities are generally considered asymptomatic. Pulse wave amplitude drop (PWAD) is a marker of autonomic nervous system (ANS) reactivity linked to cardiovascular risk. Generalized paroxysmal fast activity (GPFA) is a major EEG pattern in different epileptic conditions.
Julie Lévi‐Strauss, Valerio Frazzini, Claude Adam, Isabelle Gourfinkel‐An, Sophie Dupont, Vincent Navarro, Vi‐Huong Nguyen‐Michel   +6 more
wiley   +1 more source

The Role of the NO/cGMP Pathway and SKCa and IKCa Channels in the Vasodilatory Effect of Apigenin 7-Glucoside

Molecules
This study aimed to elucidate the vasorelaxant mechanism of action for apigenin 7-glucoside (A7G) by integrating computational and ex vivo pharmacological approaches.
Maria Luiza Fidelis da Silva, Erdi Can Aytar, Arquimedes Gasparotto Junior   +2 more
doaj   +1 more source