Results 41 to 50 of about 9,502 (211)

Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin

Advanced Healthcare Materials, EarlyView.
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi, Cristina Parisi, Federica Sodano, Ovidio Catanzano, Anna Di Porzio, Antonio Randazzo, Salvatore Sortino, Fabiana Quaglia   +7 more
wiley   +1 more source

Hydrogen Sulfide-Induced Vasodilation: The Involvement of Vascular Potassium Channels

Frontiers in Pharmacology, 2022
Hydrogen sulfide (H2S) has been highlighted as an important gasotransmitter in mammals. A growing number of studies have indicated that H2S plays a key role in the pathophysiology of vascular diseases and physiological vascular homeostasis. Alteration in
Xiao-Yu Liu, Ling-Ling Qian, Ru-Xing Wang   +2 more
doaj   +1 more source

Optical probe pressure effects on cutaneous blood flow [PDF]

, 2018
The variation of blood flow characteristics caused by the probe pressure during noninvasive studies is of particular interest within the context of fundamental and applied research. It has been shown previously that the weak local pressure induces vasodilation, whereas the increased pressure is able to stop the blood flow in the compressed area, as ...
arxiv   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Effects of repetition exercise training on vascular endothelial function in healthy men

Journal of Physical Fitness and Sports Medicine, 2022
High-intensity interval training improves the vascular endothelial function better than moderate-intensity continuous training. However, few studies have examined the effects of repetition training consisting of high-intensity exercise, followed by ...
Yasuaki Tamura, Hajime Miura, Kenichi Deguchi, Yuji Hashimoto, Junji Deguchi, Ayako Murakami, Mizuki Ishikawa   +6 more
doaj   +1 more source

A Highly Adaptable Hydrogen Bond Re‐Orientation (HyBRO) Strategy for Multiscale Vasculature Fabrication

Advanced Materials, EarlyView.
A novel hydrogen bond re‐orientation (HyBRO) strategy enables three‐dimensional (3D) printing of vascular microchannel networks with high accuracy. By switching sacrificial material interactions with nonsolvents, HyBRO prevents swelling and deformation, enabling accurate hierarchical channels spanning a tenfold size range.
Zhencheng Liao, Yu Liu, Chonghao Chen, Iek Man Lei, Lei Dong, Chunming Wang   +5 more
wiley   +1 more source

Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial-independent dilator responses in isolated aortic vessels

International Journal of Nanomedicine, 2017
Teba Mohamed,1,* Sabine Matou-Nasri,2,* Asima Farooq,3 Debra Whitehead,3 May Azzawi1 1School of Healthcare Science, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK; 2Cell and Gene Therapy Group, Medical Genomics ...
Mohamed T, Matou-Nasri S, Farooq A, Whitehead D, Azzawi M   +4 more
doaj  

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source

Ischemic Preconditioning Improves Microvascular Endothelial Function in Remote Vasculature by Enhanced Prostacyclin Production

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
BACKGROUND The mechanisms underlying the effect of preconditioning on remote microvasculature remains undisclosed. The primary objective was to document the remote effect of ischemic preconditioning on microvascular function in humans.
Nicolai Rytter, Howard Carter, Peter Piil, Henrik Sørensen, Thomas Ehlers, Frederik Holmegaard, Christoffer Tuxen, Helen Jones, Dick Thijssen, Lasse Gliemann, Ylva Hellsten   +10 more
doaj   +1 more source

Synthesis of Bimetallic (Iron–Cobalt) Single Atom Catalysts for Electrochemical Detection of Nitrites

Advanced Materials Technologies, EarlyView.
A CO2 laser‐assisted solid‐state synthesis of a bimetallic single‐atom catalyst is presented. The resulting material consists of a 3D porous graphene support with iron and cobalt atoms anchored as single atoms. Through electrochemical methods, the material's efficiency is demonstrated in the sensitive and selective determination of nitrite, mimicking ...
Guillermo Tostado‐Blazquez, Messaoud Harfouche, Jose L. Cerrillo, Abdullah Bukhamsin, Veerappan Mani, Khaled Nabil Salama   +5 more
wiley   +1 more source