Results 71 to 80 of about 25,436 (310)
The Road to Stockholm: [Dr. Bruce Merrifield] [PDF]
Rockefeller University Research Profiles are a series of scientific profiles that were published quarterly, from 1980-1990, by the Rockefeller University. Each issue features the research and achievements of an individual Rockefeller University scientist.
Bardossi, Fulvio, Schwartz, Judith N.
core +1 more source
Given the essential role of protein‐protein interactions (PPIs) in cellular signalling pathways their selective modulation is of great therapeutic interest. Mimicry of secondary structural protein elements has emerged as a promising strategy, with various scaffolds reproducing recognition surfaces of α‐helical and β‐strand/sheet proteins.
James Luccarelli+4 more
wiley +1 more source
Protein co-evolution, co-adaptation and interactions [PDF]
Co-evolution has an important function in the evolution of species and it is clearly manifested in certain scenarios such as host–parasite and predator–prey interactions, symbiosis and mutualism.
Alfonso Valencia+10 more
core +2 more sources
ABSTRACT Background Coronary artery vasospasm following coronary artery bypass grafting (CABG) is a rare but potentially life‐threatening complication that can lead to myocardial ischemia, arrhythmias, and cardiogenic shock. Nitroglycerin‐resistant vasospasm, particularly involving the left main coronary artery (LMCA), poses significant diagnostic and ...
Dina Soliman+3 more
wiley +1 more source
Comment on "The Vasopressin Loading for Refractory septic shock (VALOR) study: a prospective observational study". [PDF]
Kotani Y, Hayashi Y.
europepmc +1 more source
Angiotensin II AT1 Receptor Blockade Changes Expression of Renal Sodium Transporters in Rats with Chronic Renal Failure [PDF]
We aimed to examine the effects of angiotensin II AT1 receptor blocker on the expression of major renal sodium transporters and aquaporin-2 (AQP2) in rats with chronic renal failure (CRF).
Beutler+36 more
core +2 more sources
Herein, a sequential acyl‐thiol‐ene/S‐deacetylation protocol for selective installation of thiol residues onto synthetic peptides, on‐resin, is demonstrated. The hydrothiolation/S‐deacetylation protocol offers a novel synthetic tool for direct peptide conjugation on‐resin and for the preparation of novel disulfide containing neuropeptides displaying ...
Nikita Ostrovitsa+5 more
wiley +1 more source
Analytical methods for the quantitative determination of oxytocin [PDF]
Oxytocin is a clinically important nonapeptide that is used for the induction and/or augmentation of labor and is normally administered as a slow intravenous infusion diluted with normal saline or Ringer’s lactate solution. Oxytocin is also indicated for
Chaibva, F A, Walker, Roderick
core +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui+2 more
wiley +1 more source
Severe hyponatremia induced by the association of fluoxetine, hydrochlorothiazide andcaptopril in a young patient [PDF]
Descrevemos um caso de hiponatremia grave, com um dos níveis séricos de sódio mais baixos da literatura, secundário ao uso de fluoxetina, captopril e hidroclorotiazida.
Alves, Luíza Hama+4 more
core +2 more sources