Results 91 to 100 of about 2,628,537 (340)

Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain [PDF]

, 2006
Cassia N. Cearley, John H. Wolfe
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery [PDF]

, 1996
Tamera M. Pertmer, Tim Roberts, Joel R. Haynes   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

The dynamics of questing ticks collected for 164 consecutive months off the vegetation of two landscape zones in the Kruger National Park (1988–2002). Part III. The less commonly collected species

Onderstepoort Journal of Veterinary Research, 2011
Despite many studies regarding tick ecology, limited information on long-term changes in tick populations exist. This study assessed the long-term population dynamics of the less frequently collected questing ixodid ticks in the Kruger National Park ...
Gordon J. Gallivan, Andrea Spickett, Heloise Heyne, Arthur M. Spickett, Ivan G. Horak   +4 more
doaj   +1 more source

Generation of arbitrary cylindrical vector beams on the higher order Poincaré sphere [PDF]

, 2014
Shizhen Chen, Xinxing Zhou, Yachao Liu, Xiaohui Ling, Hailu Luo, Shuangchun Wen   +5 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Evaluation of vector competence of Culex tritaeniorhynchus and Culex pipiens pallens for Japanese encephalitis virus genotype III and V

Parasites & Vectors
Background Japanese encephalitis virus (JEV) is a major mosquito-borne pathogen, primarily transmitted by Culex tritaeniorhynchus in rural regions. In the Republic of Korea (ROK), genotype V (GV) has become the dominant JEV strain since 2010, raising ...
Ji-Young Kwon, Hyun Hee Jung, Hee Il Lee, Bo-Ram Yun   +3 more
doaj   +1 more source

Tick salivary protein Cystatin: structure, anti-inflammation and molecular mechanism

Ticks and Tick-Borne Diseases
Ticks are blood-sucking ectoparasites that secrete immunomodulatory substances in saliva to hosts during engorging. Cystatins, a tick salivary protein and natural inhibitor of Cathepsins, are attracting growing interest globally because of the ...
Xin Gao, Yuan Tian, Zi-ling Liu, Dan Li, Jia-jun Liu, Guang-xu Yu, De-yong Duan, Tao Peng, Tian-yin Cheng, Lei Liu   +9 more
doaj   +1 more source

Tropical support vector machines: Evaluations and extension to function spaces

, 2022
Ruriko Yoshida, Misaki Takamori, Hideyuki Matsumoto, Keiji Miura   +3 more
openalex   +1 more source