Results 91 to 100 of about 345,542 (292)

LOCAL AND SYSTEMIC VEGF-А PRODUCTION IN COMPLICATED PROLIFERATIVE DIABETIC RETINOPATHY

Медицинская иммунология, 2016
VEGF-A contents was studied in blood serum, lacrimal fluid, and vitreous body of patients with different clinical forms of complicated proliferative diabetic retinopathy (PDR).
V. V. Neroev, O. V. Zaytseva, N. V. Balatskaya, Z. V. Kurchaeva   +3 more
doaj   +1 more source

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma [PDF]

, 2016
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. We previously showed that the inhibition of placental growth factor (PlGF) exerts antitumour effects and induces vessel normalisation, possibly reducing hypoxia ...
Bogaerts, Eliene, Carmeliet, Peter, Devisscher, Lindsey, Geerts, Anja, Jonckx, Bart, Laukens, Debby, Libbrecht, Louis, Paridaens, Annelies, Raevens, Sarah, Van den Bussche, Anja, Van Steenkiste, Christophe, Van Vlierberghe, Hans, Vandewynckel, Yves-Paul, Verhelst, Xavier   +13 more
core   +1 more source

Dichotomous effects of VEGF-A on adipose tissue dysfunction [PDF]

Proceedings of the National Academy of Sciences, 2012
Obese fat pads are frequently undervascularized and hypoxic, leading to increased fibrosis, inflammation, and ultimately insulin resistance. We hypothesized that VEGF-A–induced stimulation of angiogenesis enables sustained and sufficient oxygen and nutrient exchange during fat mass expansion, thereby improving adipose tissue function ...
Kai, Sun, Ingrid, Wernstedt Asterholm, Christine M, Kusminski, Ana Carolina, Bueno, Zhao V, Wang, Jeffrey W, Pollard, Rolf A, Brekken, Philipp E, Scherer   +7 more
openaire   +2 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Gene Expression of VEGF-A and VEGF-C in Peripheral Blood Mononuclear Cells of Iranian Patients with Acute Myeloid Leukemia

Turkish Journal of Hematology, 2013
OBJECTIVE: The crucial role of angiogenesis in the pathophysiology of acute myeloid leukemia (AML) has been proposed. One of the key regulators of angiogenesis is the vascular endothelial growth factor (VEGF).
Mohammad Reza Aliparasti, Shohreh Almasi, Zohreh Sanaat, Aliakbar Movasaghpoor, Reza Khalili Dizaji, Homaun Sadeghi Bazargani   +5 more
doaj   +1 more source

Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo [PDF]

, 2018
Lenvatinib is an oral, multitargeted tyrosine kinase inhibitor (TKI) of VEGFR1-VEGFR3, FGFR1-FGFR4, PDGFRα, RET and v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) signaling networks involved in tumor angiogenesis.
Antonelli, Alessandro, Baldini, Enke, Bocci, Guido, Di Desidero, Teresa, Elia, Giusy, Fallahi, Poupak, Ferrari, Silvia Martina, Materazzi, Gabriele, Miccoli, Paolo, Motta, Concettina La, Orlandi, Paola, Paparo, Sabrina Rosaria, Patrizio, Armando, Piaggi, Simona, Ragusa, Francesca, Ruffilli, Ilaria, Ulisse, Salvatore   +16 more
core   +2 more sources

Role of VEGF-A in Endothelial Phenotypic Shift in Human Diabetic Retinopathy and VEGF-A-Induced Retinopathy in Monkeys

Ophthalmic Research, 2001
The endothelium-specific antigen PAL-E, associated with transport vesicles in non-barrier endothelium, is almost absent from barrier capillaries in the normal brain and retina. We have recently demonstrated that only leaking retinal capillaries in diabetic retinopathy (DR) in humans characteristically express PAL-E.
Hofman, P., Blaauwgeers, H. G., Vrensen, G. F., Schlingemann, R. O.   +3 more
openaire   +2 more sources

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source

Correlation between VEGF-A Serum Levels and Urine Albumin to-Creatinine Ratio in Diabetic Kidney Disease Patients

Jurnal Penyakit Dalam Indonesia
Introduction. Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus, characterized by persistent albuminuria and a progressive decline in glomerular filtration rate (GFR), making it a leading cause of chronic kidney ...
Hannie Qalbina Syaiful, Drajad Priyono, Harnavi Harun, Arina Widya Murni, Akmal M.Hanif, Eifel Faheri, Arnelis, Vesri Yoga   +7 more
doaj   +1 more source

STUDY OF VEGF-A AND TGF-Β LEVELS IN BIOPTATES OF SQUAMOUS CELL CARCINOMA OF THE TONGUE AND MOUTH FLOOR MUCOSA IN POLYCHEMOTHERAPY WITH MONOCLONAL ANTIBODIES – CETUXIMAB

Исследования и практика в медицине, 2019
Aim. Study of VEGF-A and TGF-β growth factors in tumor tissue bioptates in patients with squamous cell carcinoma of the tongue and floor of the oral cavity depending on the effectiveness of polychemotherapy targeted therapy with cetuximab.Patients and ...
O. I. Kit, E. M. Frantsiyants, I. V. Neskubina, L. Yu. Vladimirova, A. A. Lyanova, Yu. A. Pogorelova, E. V. Shalashnaya, M. A. Еngibaryan, Yu. S. Sidorenko   +8 more
doaj   +1 more source