Results 101 to 110 of about 113,958,312 (241)
, 2022 The phase III MAX clinical trial randomised patients with metastatic colorectal cancer (mCRC) to receive first-line capecitabine chemotherapy alone or in combination with the anti-VEGF-A antibody bevacizumab (± mitomycin C).
Niall Tebbutt (13124949) +15 more
core +1 more source
Biotechnology & Biotechnological Equipment, 2019 The aim of the present study was to investigate whether miRNA (miRNA or miR)-125a-5p regulates angiogenesis in hepatocellular carcinoma (HCC) via VEGF-A. Reverse transcription-quantitative polymerase chain reaction was used to determine the expression of
Jingjing Liu, Changming Tao
doaj +1 more source
Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
Immunohistochemical Assessment of Proliferation, Angiogenesis, and Viral Markers in Recurrent Laryngeal Papillomatosis [PDF]
Modern MedicineRecurrent laryngeal papillomatosis (RLP) is a benign but clinically aggressive condition, characterized by frequent recurrences and significant morbidity.
Daniela CERNEV +3 more
doaj +1 more source
Advanced Science, EarlyView.A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait +7 more
wiley +1 more source
Effect of vascular endothelial growth factors A, C, and D in HIV-associated pre-eclampsia
Hypertension in Pregnancy, 2017 Objective: To measure and correlate the level of vascular endothelial growth factors A, C, and D in HIV-associated pre-eclampsia. Methods: VEGF-A, VEGF-C, and VEGF-D were measured in serum of 76 normotensive and pre-eclamptic pregnant women stratified by
Gugulethu Promise Shange +2 more
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification [PDF]
, 2012 Adult mesenchymal stromal/stem cells (MSCs) are a valuable source of multipotent progenitors for tissue engineering and regenerative medicine, but may require to be genetically modified to widen their efficacy in therapeutic applications.
Melly, L. +26 more
core +1 more source
Advanced Science, EarlyView.This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li +14 more
wiley +1 more source
Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
Advanced Science, EarlyView.The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source