Results 121 to 130 of about 383,810 (341)
Advanced Functional Materials, EarlyView.Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu +13 more
wiley +1 more source
Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]
, 2016 Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core
The impact of KRAS mutations on VEGF-A production and tumour vascular network [PDF]
, 2016 Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is also different, with an increased anaerobic glycolytic
Arbós i Via, Maria Antònia +5 more
core +1 more source
Journal of Inflammation Research, 2022 Fengjin Shao,1– 3 Rui Liu,1 Xun Tan,1– 4 Qiaoyan Zhang,1– 3 Lujie Ye,1– 3 Bingxuan Yan,1– 3 Ying Zhuang,1,2,4 Jiaxue Xu1,2,4 1Department of Veterinary Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China; 2Veterinary ...
Shao F +7 more
doaj
Advanced Functional Materials, EarlyView.ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian +5 more
wiley +1 more source
Regulation of vascular endothelial growth factor bioactivity in patients with acute lung injury [PDF]
, 2005 Background: Reduced bioactive vascular endothelial growth factor (VEGF) has been demonstrated in several inflammatory lung conditions including the acute respiratory distress syndrome (ARDS).
Armstrong, L. +6 more
core +2 more sources
Biotechnology & Biotechnological Equipment, 2019 The aim of the present study was to investigate whether miRNA (miRNA or miR)-125a-5p regulates angiogenesis in hepatocellular carcinoma (HCC) via VEGF-A. Reverse transcription-quantitative polymerase chain reaction was used to determine the expression of
Jingjing Liu, Changming Tao
doaj +1 more source
Advanced Functional Materials, EarlyView.Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni +8 more
wiley +1 more source
Role of VEGF-A in Pancreatic Beta Cells
Endocrine Journal, 2010 The islet contains a dense vascular structure of several features. The expression of vascular endothelial growth factor (VEGF)-A in beta cells is indispensable for the formation of this structure. Thus, the beta cell-specific VEGF-A-deficient mouse (RIP-Cre:Vegf(fl/fl)) is useful for studying the role of the islet vasculature on the function of islets ...
openaire +3 more sources
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source