Embryonic Vascular Toxicity of Calotropis Procera; Evaluation of Early Anti-Vasculogenic Property and Molecular Aspects Using A Chick’s Extra-Embryonic Membrane Model [PDF]
Background: Calotropis procera Aiton (C. procera) is used in folk medicine to cure various diseases. However, the use of herbs in human medicine is sometimes associated with adverse effects.
Hadi Tavakkoli +6 more
doaj +1 more source
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival [PDF]
There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5 ...
Chaddah, R +7 more
core +3 more sources
Single nucleotide polymorphisms: rs833061, rs699947, and rs35569394, and the expression of the vascular endothelial growth factor gene in Moroccan patients with lung cancer [PDF]
Aim: Angiogenesis is a universal hallmark of all cancers involving a variety of proteins including vascular endothelial growth factor (VEGF). Extensive studies have explored the potential implications of single nucleotide polymorphisms (SNPs) within VEGF-
Younes El Founini +9 more
doaj +1 more source
Angiogenic potential of circulating blood neutrophils in endometrial cancer
Neutrophils play an important role in carcinogenesis, mediating inflammation, immunosuppression and metastasis. A dual role of neutrophils in regulation of angiogenesis has been shown.
T. V. Abakumova +3 more
doaj +1 more source
Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice [PDF]
Trypanosoma cruzi infection induces an intense inflammatory response in diverse host tissues. The immune response and the microvascular abnormalities associated with infection are crucial aspects in the generation of heart damage in Chagas disease.
Carta, Davide +9 more
core +2 more sources
VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels [PDF]
We thank Vann Bennett and Daizing Zhou (Department of Biochemistry, Duke University Medical Center) for the design and generation of the Brn3bCre knock-in mice.
Bruce, Freyja +7 more
core +2 more sources
Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Chillo, Omary +6 more
core +3 more sources
Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization. [PDF]
Vascular endothelial growth factor A (VEGF-A) is a master regulator of angiogenesis, vascular development and function. In this study we investigated the transcriptional regulation of VEGF-A-responsive genes in primary human aortic endothelial cells ...
Benner, Christopher +9 more
core +1 more source
Glucose, VEGF-A, and Diabetic Complications [PDF]
Diabetes is a widespread disease with multiple complications that affect both the microvasculature and macrovasculature. In the past decade, studies of the underlying factors in diabetic complications have resulted in an interesting dilemma: both microvascular insufficiencies and microvascular proliferative diseases plague diabetic patients, sometimes ...
openaire +2 more sources
Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]
Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Plate, Karl H. +2 more
core +1 more source

