Results 31 to 40 of about 316,152 (254)
VEGF-A, VEGF-C, and VEGF-D in Colorectal Cancer Progression
We aimed to assess the relationship of the angiogenic cytokines VEGF-A, VEGF-C, and VEGF-D and their receptors VEGFR-2 and VEGFR-3 in the adenoma-carcinoma sequence and in metastatic spread of colorectal cancer (CRC). mRNA expression levels were measured using semi-quantitative reverse transcription polymerase chain reaction in 70 CRC (35 with paired ...
Mark L. George +6 more
openaire +3 more sources
VEGF₁₂₁b and VEGF₁₆₅b are weakly angiogenic isoforms of VEGF-A.
Different isoforms of VEGF-A (mainly VEGF₁₂₁, VEGF₁₆₅ and VEGF189) have been shown to display particular angiogenic properties in the generation of a functional tumor vasculature. Recently, a novel class of VEGF-A isoforms, designated as VEGF(xxx)b, generated through alternative splicing, have been described.
Pio, R. (Rubén) +9 more
openaire +3 more sources
The significance of some growth factors in the pathogenesis of endocrine ophthalmopathy
Aim. The purpose of this work was to study the role of transforming growth factors (TGF-, FGF-2, VEGF-A) during endocrine ophthalmopathy (EOC). Materials and methods. The study 119 patients with endocrine ophthalmopathy were examined, at the age of 48
Vladimir V. Charinzev +3 more
doaj +1 more source
Regulatory Role of microRNAs in Tumor Angiogenesis
The process of neoangiogenesis is one of the classic hallmarks of a cancer. Its intricate mechanisms have long been one of the major domains in cancer research and a hope for a therapeutic breakthrough.
Popov T. +7 more
doaj +1 more source
VEGF in the Nervous System [PDF]
Vascular endothelial growth factor (VEGF, VEGFA) is critical for blood vessel growth in the developing and adult nervous system of vertebrates. Several recent studies demonstrate that VEGF also promotes neurogenesis, neuronal patterning, neuroprotection and glial growth.
Jeffrey M, Rosenstein +2 more
openaire +2 more sources
Angiogenic potential of circulating peripheral blood neutrophils in kidney cancer
The role of neutrophils in kidney cancer is currently being studied. Their role in carcinogenesis is ambiguous. As one of the most abundant blood leukocytes, neutrophils play an important role in cancer progression through multiple mechanisms, including ...
I. R. Myagdieva +4 more
doaj +1 more source
Analysis of VEGF-A/VEGFR1/VEGFR2 gene expression in patients with myelodysplastic syndrome [PDF]
Aim. To assess the significance of gene expression of the vascular endothelial growth factor-A (VEGF-A) and its interacting receptors VEGFR1 and VEGFR2 as potential diagnostic and prognostic molecular markers in patients with myelodysplastic syndrome ...
N N Kalitin +3 more
doaj +1 more source
Role of VEGF in Organogenesis [PDF]
The cardiovascular system, consisting of the heart, blood vessels and hematopoietic cells, is the first organ system to develop in vertebrates and is essential for providing oxygen and nutrients to the embryo and adult organs. Work done predominantly using the mouse and zebrafish as model systems has demonstrated that Vascular Endothelial Growth Factor
openaire +2 more sources
OBJECTIVE: The purpose of this study was to investigate the effects of resistance training on angiogenesis markers of visceral adipose tissue in ovariectomized rats. METHOD: Adult Sprague-Dawley female rats were divided into four groups (n=6 per group):
Camila do Valle Gomes-Gatto +5 more
doaj +1 more source
Aim: creation of a method for predicting the development of varicose veins of the lower extremities and its recurrence.Object and methods. 2 independent studies of patients with C2-C6 varicose veins of the lower extremities (CEAP-classifier) were ...
G. V. Yarovenko +3 more
doaj +1 more source

