Results 91 to 100 of about 20,098,805 (300)

The role of angio-/lymphangiogenic factors VEGF, VEGF-C and VEGF-D during cervical carcinogenesis and their use for diagnostics

, 2009
Angiogenese und Lymphangiogenese haben sich in den letzten Jahrzehnten als hoch bedeutsam für die Entstehung und Progression von Tumorerkrankungen erwiesen.
Füger, Andrea Sylvia
core   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

The prognostic value of detection of serum VEGF-C level and lymphangiogenesis in mediastinal lymph nodes in the patients with lung cancer

Chinese Journal of Lung Cancer, 2008
Background and objective There is still lack of special prognostic factor on lung cancer, this study will explore the prognostic value of serum VEGF-C level and lymphangiogenesis of primary cancer and mediastinal lymph nodes in the patients with lung ...
Yang SHENTU, Tiancheng ZHAO, Zhengping DING, Yunzhong ZHOU   +3 more
doaj  

Vascular endothelial growth factor (VEGF) receptor-2 signaling mediates VEGF-C(deltaNdeltaC)- and VEGF-A-induced angiogenesis in vitro

, 2003
Angiogenesis and lymphangiogenesis are regulated by members of the vascular endothelial growth factor (VEGF) family of cytokines, which mediate their effects via tyrosine kinase VEGF receptors -1, -2, and -3.
Wang, X, Tille, J-C, Ferrara, N, Sleeman, JP, Hicklin, DJ, Alitalo, K, Lipson, KE, Eriksson, U,, Zhu, Z, McMahon, G   +9 more
core   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

Advanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet, Charles Handschin, Theo Desigaux, Nathalie Dusserre, Marie‐Laure Stachowicz, Shane Fennell, Malou Lea, Silvia Arcucci, Benoît Thibault, Jean‐Christophe Fricain, Julie Guillermet‐Guibert, Hugo Oliveira   +11 more
wiley   +1 more source

MMP13 Regulates Aggressiveness of Pediatric Multiple Myeloma Through VEGF-C

Cellular Physiology and Biochemistry, 2015
Background/Aims: Even though the blood and lymphatic vascular systems are both involved in the occurrence of cancer metastases, it is believed that lymphatic system is primarily responsible for the initial metastasis.
Lingyun Xu, Kai Sun, Min Xia, Xiaoli Li, Yanming Lu   +4 more
doaj   +1 more source

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li, Ke Wu, Yangyang Lu, Qinglan Xia, Jialong Chen, Yifan Zhang, Zhaoyu Chen, Zhiyuan She, Junjin Jie, Juzi Xia, Muran Zhou, Aimei Zhong   +11 more
wiley   +1 more source

Vascular Endothelial Growth Factor (VEGF-C) Protein Expression Related with Lymphangiogensis in Iraqi Cervical Cancer Patients

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2019
Objective: Metastatic spread of tumor cells to distant organs is the leading cause of mortality from cancer. Although metastatic tumor spread can occur via a different mechanism. lymphangiogenic factors recognized were vascular endothelial growth factor
Yasser kadhim Hashem Al-Zwaini, Wassan Abdul Kareem Abbas, Sahira Hamdan Abbas Alzubaidi, Azza Nazar Dhannoon Aljaleeli, Suhad Faisal Hatem Al-Mugdadi   +4 more
doaj   +1 more source

Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3

, 2010
Vascular sprouting is a key process-driving development of the vascular system. In this study, we show that neuropilin-2 (Nrp2), a transmembrane receptor for the lymphangiogenic vascular endothelial growth factor C (VEGF-C), plays an important role in ...
Yuan, Li, Mak, Judy, Toro Estévez, Raquel del, Pardanaud, Luc, Kasman, Ian, Caunt, Maresa, Bagri, Anil, Xu, Yunling   +7 more
core   +1 more source