Results 261 to 270 of about 20,098,805 (300)

Role of VEGF-C and VEGF-D in lymphangiogenesis in gastric cancer

International Journal of Clinical Oncology, 2005
The molecular mechanisms of lymphangiogenesis induced by vascular endothelial growth factor (VEGF)-C and VEGF-D in gastric cancer were studied.VEGF-C and VEGF-D gene expression vectors were transfected into the gastric cancer cell line KKLS, which did not originally express VEGF-C and VEGF-D, and stable transfectants (KKLS/VEGF-C and KKLS/VEGF-D) were ...
Yutaka, Yonemura, Yoshio, Endo, Kayoko, Tabata, Taiichi, Kawamura, Hyo-Yung, Yun, Etsurou, Bandou, Takuma, Sasaki, Masahiro, Miura   +7 more
openaire   +2 more sources

The prognostic significance of VEGF-C and VEGF-A in non-Hodgkin lymphomas

Leukemia & Lymphoma, 2009
Angiogenesis and lymphangiogensis are important in the proliferation and survival of the malignant hemeopoietic neoplasms. The aim of this study is to determine the prognostic role of angiogenesis and lymphangiogenesis in the development of lymphoma. For this aim, VEGF-A and VEGF-C were explored by immunohistochemistry in 177 cases.
Paydas S., Seydaoglu G., Ergin M., Erdogan S., Yavuz S.   +4 more
openaire   +3 more sources

Serum levels of VEGF and VEGF-C in patients with endometrial cancer

European Cytokine Network, 2011
Endometrial cancer (EC) is the most common type of uterine cancer. A dualistic model of endometrial tumorigenesis serves as a useful way of categorizing these cancers in terms of both etiology and clinical behavior. There are two types of EC: type I and type II. Type I is so-called estrogen-dependent, and appears mostly in pre- and perimenopausal women,
Bozena, Dobrzycka, Slawomir J, Terlikowski, Oksana, Kowalczuk, Marek, Kulikowski, Jacek, Niklinski   +4 more
openaire   +2 more sources

The balance of autocrine VEGF-A and VEGF-C determines podocyte survival

American Journal of Physiology-Renal Physiology, 2009
Podocytes are an important component of the glomerular filtration barrier and are the major source of vascular endothelial growth factor (VEGF) in the glomerulus. The role of VEGF for the phenotype of the glomerular endothelium has been intensely studied; however, the direct effects of autocrine VEGF on the podocyte are largely unknown.
Janina, Müller-Deile, Kirstin, Worthmann, Moin, Saleem, Irini, Tossidou, Hermann, Haller, Mario, Schiffer   +5 more
openaire   +2 more sources

The role of VEGF-C staining in predicting regional metastasis in melanoma

Virchows Archiv, 2008
Sentinel lymph node status is the most important prognostic factor in primary melanoma. The number of melanoma-associated lymphatic vessels has been associated with sentinel lymph node status and survival. Vascular endothelial growth factor-C (VEGF-C) is found to promote tumour-associated lymphatic vessel growth.
Boone, B., Blokx, W.A.M., Bacquer, D. De, Lambert, J., Ruiter, D.J., Brochez, L.   +5 more
openaire   +3 more sources

VEGF-C expression in breast cancer

2019
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Yavuz, Sinan, Paydas, Semra, Zorludemir, Suzan, Disel, Umut, Sahin, Berksoy   +4 more
openaire   +1 more source

Suppression of lymphangiogenesis using VEGF-C trap

2016
The lymphatic system is responsible for controlling systemic fluid buildup. Lymphangiogenesis is a dynamic process involving sprouting, and maintaining new lymphatic vasculature. Vascular endothelial growth factor C (VEGF-C) is as a key growth factor that induces lymphangiogenesis by binding VEGF receptors 2 and 3 (VEGFR-2 and VEGFR-3).
openaire   +1 more source

Treatment of Renal Cell Carcinoma: Current Status and Future Directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Coelho Barata
exaly  

VEGF-C

2011
openaire   +1 more source

Evidence for Pro-Angiogenic Functions of VEGF-Ax

Cell, 2016
Napoleone Ferrara, Eric Nudleman, Hong Xin   +2 more
exaly