Results 91 to 100 of about 14,728,452 (289)

Peritumoral lymphangiogenesis induced by vascular endothelial growth factor C and D promotes lymph node metastasis in breast cancer patients

World Journal of Surgical Oncology, 2012
Background Mounting clinical and experimental data suggest that the migration of tumor cells into lymph nodes is greatly facilitated by lymphangiogenesis.
Zhao Ying-Chun, Ni Xiao-Jian, Li Yong, Dai Min, Yuan Zhong-Xu, Zhu Yong-Yun, Luo Chuan-Yu   +6 more
doaj   +1 more source

VEGF-D-geeninsiirron vaikutus rotan lihasvamman paranemiseen [PDF]

, 2015
Yli puolet urheiluvammoista on lihasvammoja. Nykyisen hoitokäytännön mukaan niitä hoidetaan pääsääntöisesti konservatiivisesti. Lääkkeellistä hoitoa lihasvammoihin ei ole, kuten ei myöskään muihin tuki- ja liikuntaelimistön traumaattisiin vammoihin ...
Harmanen, Laura
core  

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

VEGF-D deficiency in mice does not affect embryonic or postnatal lymphangiogenesis but reduces lymphatic metastasis. [PDF]

, 2009
peer reviewedVascular endothelial growth factor-D (VEGF-D) is one of the two ligands of the VEGFR-3 receptor on lymphatic endothelial cells. Gene-silencing studies in mice and Xenopus tadpoles recently showed that the role of endogenous VEGF-D in ...
Marconcini, L., Wallays, G., Noel, A., Van Nuffelen, A., Van Nuffelen, An, Dettori, Daniela, Souffreau, J., Koch, Marta, Oliviero, S., Koch, M., och, M., Foidart, J. M., Marconcini, Lucia, Carmeliet, Peter, Bruyère, F., Moons, L., Foidart, Jean-Michel, Souffreau, Joris, Dewerchin, Mieke, Wallays, Goedele, Oliviero, Salvatore, Dewerchin, M., Moons, Lieve, Carmeliet, P., Dettori, D., Bruyere, Françoise, Noël, Agnès   +26 more
core   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Single nucleotide polymorphisms: rs833061, rs699947, and rs35569394, and the expression of the vascular endothelial growth factor gene in Moroccan patients with lung cancer [PDF]

Exploration of Medicine
Aim: Angiogenesis is a universal hallmark of all cancers involving a variety of proteins including vascular endothelial growth factor (VEGF). Extensive studies have explored the potential implications of single nucleotide polymorphisms (SNPs) within VEGF-
Younes El Founini, Sara Hafidi, Hind Dehbi, Mohammed Attaleb, Mehdi Karkouri, Souheil Boubia, Mohammed Ridai, Fadila Guessous, Mohammed El Mzibri, Imane Chaoui   +9 more
doaj   +1 more source

VEGF-A and VEGFR2 as candidate pathway in NVU OPC recruitment.

, 2019
a-i Representative confocal images of cerebral cortex sections from EAE-affected WT mice, immunolabelled for growth factors and their receptors: VEGF-A and its receptor VEGFR2 (a-c), FGF2 and its receptor FGFR1 (d-f), PDGF-AA/PDGFRα (g, h) and TGFβ (i ...
Carlotta Alias (6459365), Giovanni Ferrara (5840474), Daniela Virgintino (502069), Tiziana Annese (6211481), Sara Morando (369232), Francesco Girolamo (502060), Maria Trojano (301639), Mariella Errede (502063), Giovanna Longo (4923058), Antonio Uccelli (8756), Nicole Kerlero de Rosbo (195546)   +10 more
core   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

Diagnostic performance of vascular endothelial growth factor D in severity stratification of pediatric COVID-19 and multisystem inflammatory syndrome in children

Frontiers in Immunology
IntroductionIn recent years, vascular endothelial growth factor D (VEGF-D) has been recognized as a promising biomarker for disease severity stratification in coronavirus disease, as well as an indicator of endothelial dysfunction, hypoxia, and ...
Kateryna Kozak, Halyna Pavlyshyn
doaj   +1 more source