Results 111 to 120 of about 14,728,452 (289)

Circulating Levels of Vegf-A, VEGF-D and soluble VEGF-A Receptor (sFlt-1) in Human Breast Cancer

The International Journal of Biological Markers, 2004
As circulating levels of vascular endothelial growth factor (VEGF-A) are raised in malignancy, the aim of this study was to investigate whether similar changes occur in two related factors, VEGF-D and the soluble VEGF-A receptor Flt-1 (sFlt-1 ...
F.J. Hoar, G.Y.H. Lip, F. Belgore, P.S. Stonelake   +3 more
doaj   +1 more source

Correction: EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory. [PDF]

Cell Mol Life Sci, 2023
Barth K, Vasić V, McDonald B, Heinig N, Wagner MC, Schumann U, Röhlecke C, Bicker F, Schumann L, Radyushkin K, Baumgart J, Tenzer S, Zipp F, Meinhardt M, Alitalo K, Tegeder I, Schmidt MHH.   +16 more
europepmc   +1 more source

Monoclonal antibodies to vascular endothelial growth factor-D block its interactions with both VEGF receptor-2 and VEGF receptor-3

, 2000
Vascular endothelial growth factor-D (VEGF-D), the most recently discovered mammalian member of the VEGF family, is an angiogenic protein that activates VEGF receptor-2 (VEGFR-2/Flk1/KDR) and VEGFR-3 (Flt4).
Stacker, S A, Domagala, T, Geleick, D M, Murphy, R, Scott, A M, Catimel, B, Nice, E C, Alitalo, K, Mäkinen, Taija,, Caesar, C, Achen, M G, Roufail, S   +11 more
core  

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Vascular Endothelial Growth Factor C and D Signaling Pathways as Potential Targets for the Treatment of Neovascular Age-Related Macular Degeneration: A Narrative Review

Ophthalmology and Therapy
The development of treatments targeting the vascular endothelial growth factor (VEGF) signaling pathways have traditionally been firstly investigated in oncology and then advanced into retinal disease indications. Members of the VEGF family of endogenous
Ian M. Leitch, Michael Gerometta, David Eichenbaum, Robert P. Finger, Nathan C. Steinle, Megan E. Baldwin   +5 more
doaj   +1 more source

The role of single nucleotide polymorphisms of VEGF gene in the development of cardiovascular diseases

Медицинская иммунология
Cardiovascular diseases (CVD) are the main cause of mortality in general population. Pathophysiology underlying CVD development includes inflammation, endothelial dysfunction, oxidative stress, atherosclerosis, fibrosis, dyslipidemia and thromboembolism.
A. S. Gaffarova, I. A. Yatskov, V. A. Beloglazov, E. S. Ageyeva, E. M. Dolya   +4 more
doaj   +1 more source

Something not so new for lymphangioleiomyomatosis: is VEGF-D a glass half empty or half full? [PDF]

J Bras Pneumol, 2022
Amaral AF, Carvalho CRR, Baldi BG.
europepmc   +1 more source

The lymphangiogenic growth factors VEGF-C and VEGF-D. Part 1: Fundamentals and embryonic development

, 2013
English version of the review "Die lymphangiogenen Wachstumsfaktoren VEGF-C und VEGF-D. Teil 1. Grundlagen und Embryonalentwicklung.
Krebs, R., Jeltsch, M.
core   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory. [PDF]

Cell Mol Life Sci, 2023
Barth K, Vasić V, McDonald B, Heinig N, Wagner MC, Schumann U, Röhlecke C, Bicker F, Schumann L, Radyushkin K, Baumgart J, Tenzer S, Zipp F, Meinhardt M, Alitalo K, Tegeder I, Schmidt MHH.   +16 more
europepmc   +1 more source