Results 121 to 130 of about 21,287,561 (278)

Dissecting VEGFR-2 and VEGFR-3 function : VEGFR-3 mediates lymphangiogenic signals

, 2002
ei ...
Veikkola, Tanja
core  

Immunolocalization of VEGF and VEGFR 1 & 2 in embryonic lung tissues

The FASEB Journal, 2010
Eb 2010 Abstract The role of vascular endothelial growth factor (VEGF) and its receptors 1 and 2 (flt and flk) have been identified in mammalian lung development but there are few studies concerning their role in avian lung.
Rosie Thecla McNeil, John N Maina, Beverly Kramer   +2 more
openaire   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Activated VEGFR-1 and VEGFR-2 by UVA both contribute to the survival of keratinocytes via subsequent activation of ERK1/2 and Akt.

, 2013
(a) Keratinocytes were incubated with or without neutralizing antibodies against VEGFR-1 (A-VEGFR-1, 5 µg/ml) and VEGFR-2 (AVEGFR-2, 5 µg/ml) 24 h after treatment of 0 or 10 J/cm2 UVA, and cell apoptosis rate was examined by flow cytometry.
Zhong-Fa Lu (285979), Sui-Qing Cai (285980), Jian-Wei Zhu (285977), Dan Luo (192943), Xian-Jie Wu (285978), Min Zheng (131026)   +5 more
core   +1 more source

New perspectives on VEGF signalling in Alzheimer's disease

Brain Pathology, EarlyView.
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery, Seth Love, J. Scott Miners   +2 more
wiley   +1 more source

Representative immunolocalization of VEGFR-1 (A–B), VEGFR-2 (C, D and E) and CD31 (F).

, 2012
Placental villi from a normal pregnant women (A, C, E and F) and from a preeclamptic women (B–D): VEGFR-1 is expressed in the cytotrophoblasts, syncytiotrophoblasts (arrow) and also in some endothelial cells (white arrow head).
Frédéric Goffin (178225), Jeanne Le Goarant (178211), Christel Pequeux (178200), Frédéric Chantraine (178216), Agnès Noël (178222), Vassilis Tsatsaris (86940), Capucine Coulon (178204), Carine Munaut (178192), Sophie Lorquet (178196), Jean-Michel Foidart (43337), Damien Subtil (178230)   +10 more
core   +1 more source

Immunohistochemical study of VEGF-A, VEGFR-1, VEGFR-2 and CD34 expression in сolorectal adenocarcinoma progression

Patologìâ, 2019
Aim – to study VEGF-A, VEGFR-1, VEGFR-2 and CD34 immunohistochemical expression on the I, II, III, IV stages (pTNM) of colorectal adenocarcinoma development. Materials and methods.
M. A. Shyshkin
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Role of the NF-kB/parkin/vegfr-1 pathway associated with hypoxic-ischemic insult in germinal matrix samples of newborn infants. [PDF]

Rev Paul Pediatr, 2023
Ghirelli EA, Silva FPGD, Oricil AGG, Paula CBV, Nagashima S, Oldenburg Neto CF, Storti E, Sakiyama FYR, Kayano RM, Sakiyama RR, Moreira VDS, Sotomaior VS, Noronha L.   +12 more
europepmc   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source