Results 121 to 130 of about 29,745,998 (266)

The Role of VEGFR-1 During Murine Postnatal Angiogenesis

open access: yes, 2011
Angiogenesis is the process by which new blood vessels emerge from existing vessels. Failure to mimic the complex angiogenic process and produce natural blood vessels is one of the main obstacles preventing advancements in the fields of pro-angiogenic ...
Ho, Vivienne Che-Mei
core   +1 more source

Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies

open access: yesCancer Science, EarlyView.
Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang   +6 more
wiley   +1 more source

A Specific tRNA Half, 3'tiRNA‐GlyGCC, Regulates Hypoxic Pulmonary Artery Smooth Muscle Cell Proliferation via Myrf‐Mediated Endoplasmic Reticulum Stress

open access: yesCell Proliferation, EarlyView.
A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang   +11 more
wiley   +1 more source

Role of the NF-kB/parkin/vegfr-1 pathway associated with hypoxic-ischemic insult in germinal matrix samples of newborn infants. [PDF]

open access: yesRev Paul Pediatr, 2023
Ghirelli EA   +12 more
europepmc   +1 more source

Activated VEGFR-1 and VEGFR-2 by UVA both contribute to the survival of keratinocytes via subsequent activation of ERK1/2 and Akt.

open access: yes, 2013
(a) Keratinocytes were incubated with or without neutralizing antibodies against VEGFR-1 (A-VEGFR-1, 5 µg/ml) and VEGFR-2 (AVEGFR-2, 5 µg/ml) 24 h after treatment of 0 or 10 J/cm2 UVA, and cell apoptosis rate was examined by flow cytometry.
Zhong-Fa Lu (285979)   +5 more
core   +1 more source

Biliary Abnormality on Imaging During Lenvatinib Plus Hepatic Arterial Infusion Chemotherapy With Cisplatin for Hepatocellular Carcinoma: A Pilot Descriptive Study

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai   +10 more
wiley   +1 more source

Representative immunolocalization of VEGFR-1 (A–B), VEGFR-2 (C, D and E) and CD31 (F).

open access: yes, 2012
Placental villi from a normal pregnant women (A, C, E and F) and from a preeclamptic women (B–D): VEGFR-1 is expressed in the cytotrophoblasts, syncytiotrophoblasts (arrow) and also in some endothelial cells (white arrow head).
Frédéric Goffin (178225)   +10 more
core   +1 more source

Understanding exosomes in diabetic wound healing

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad   +4 more
wiley   +1 more source

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