Results 131 to 140 of about 21,287,561 (278)
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
, 2011 Supplementary Figure 1 from Assessing the Activity of Cediranib, a VEGFR-2/3 Tyrosine Kinase Inhibitor, against VEGFR-1 and Members of the Structurally Related PDGFR ...
Kirsty Ratcliffe (14981885) +19 more
core +1 more source
The Association of Soluble VEGFR-1 Serum Level and Genetic (rs7993418) Polymorphism with In Vitro Fertilization and Embryo Transfer Outcome in the Population of Northern Iran. [PDF]
J Reprod Infertil, 2023 Moeinfar S +4 more
europepmc +1 more source
Cancer Science, EarlyView.An immune dysfunction score (IDS) provides independent prognostic information in MDS and CMML, complements current risk models, mirrors disease changes, and reflects underlying immune impairment. IDS may also highlight therapeutic sensitivities, supporting its use as a practical biomarker for risk stratification and clinical follow‐up.
Yu‐Hung Wang +16 more
wiley +1 more source
Cancer Science, EarlyView.The dose escalation part of the first‐in‐human study of E7130 in patients with advanced solid tumors determined the Recommended Phase 2 Dose of E7130 (480 μg/m2 Q3W). The dose expansion part (presented here) examined safety/preliminary efficacy in patients with squamous cell carcinoma of the head and neck and urothelial carcinoma.
Nobuaki Matsubara +15 more
wiley +1 more source
Immature B cell malignancies synthesize VEGF, VEGFR-1 (Flt-1) and VEGFR-2 (KDR)
, 2004 Expression of VEGF and VEGFR support a role for angiogenic pathways in the pathogenesis of some hematological malignances. Our goal was to determine if expression of these angiogenic molecules also extend to childhood precursor B cell acute lymphoblastic
Al-Hussein, Khalid +5 more
core
Hypoxia differentially up regulates VEGFR-1 in SMC.
, 2015 A. RT-PCR was used to determine hypoxia-induced changes in VEGFR-1 transcript levels. Representative gel showing VEGFR-1 mRNA levels in V-SMC and A-SMC under normoxia and hypoxia. B.
Steve M. Santilli (797476) +5 more
core +1 more source
Cell Proliferation, EarlyView.A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang +11 more
wiley +1 more source
The Role of VEGFR-1 During Murine Postnatal Angiogenesis
, 2011 Angiogenesis is the process by which new blood vessels emerge from existing vessels. Failure to mimic the complex angiogenic process and produce natural blood vessels is one of the main obstacles preventing advancements in the fields of pro-angiogenic ...
Ho, Vivienne Che-Mei
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